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Molecular mechanisms affecting fibrin structure and stability

Arteriosclerosis, thrombosis, and vascular biology, 2011-03, Vol.31 (3), p.494-499

Lord, Susan T

2011

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The molecular origins of the mechanical properties of fibrin

Biophysical chemistry, 2010-11, Vol.152 (1), p.15-20

2010

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Submillisecond Elastic Recoil Reveals Molecular Origins of Fibrin Fiber Mechanics

Biophysical journal, 2013-06, Vol.104 (12), p.2671-2680

2013

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Stiffening of Individual Fibrin Fibers Equitably Distributes Strain and Strengthens Networks

Biophysical journal, 2010-04, Vol.98 (8), p.1632-1640

2010

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Fibrinogen and fibrin: scaffold proteins in hemostasis

Current opinion in hematology, 2007-05, Vol.14 (3), p.236-241

Lord, Susan T

2007

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Factor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin α-chain crosslinking

Blood, 2015-10, Vol.126 (16), p.1940-1948

2015

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Influence of Glutathione and its Derivatives on Fibrin Polymerization

Biomacromolecules, 2008-07, Vol.9 (7), p.1876-1882

2008

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Coming full circle with factor XIII

Blood, 2011-03, Vol.117 (12), p.3255-3256

Lord, Susan T.

2011

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The isolation of fibrinogen monomer dramatically influences fibrin polymerization

Thrombosis research, 2013-06, Vol.131 (6), p.e258-e263

2013

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Mouse models in coagulation

Thrombosis and haemostasis, 2002-04, Vol.87 (4), p.563-574

2002

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Substitution of the Human αC Region with the Analogous Chicken Domain Generates a Fibrinogen with Severely Impaired Lateral Aggregation: Fibrin Monomers Assemble into Protofibrils but Protofibrils Do Not Assemble into Fibers

Biochemistry (Easton), 2011-10, Vol.50 (42), p.9066-9075

2011

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Calcium-Binding Site β2, Adjacent to the “b” Polymerization Site, Modulates Lateral Aggregation of Protofibrils during Fibrin Polymerization

Biochemistry (Easton), 2004-03, Vol.43 (9), p.2475-2483

2004

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Does Topology Drive Fiber Polymerization?

Biochemistry (Easton), 2014-12, Vol.53 (49), p.7824-7834

2014

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Evidence that αC Region Is Origin of Low Modulus, High Extensibility, and Strain Stiffening in Fibrin Fibers

Biophysical journal, 2010-11, Vol.99 (9), p.3038-3047

2010

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Dynamic Regulation of Fibrinogen: Integrin αIIbβ3 Binding

Biochemistry (Easton), 2010-11, Vol.49 (43), p.9217-9225

2010

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Hydrodynamic characterization of recombinant human fibrinogen species

Thrombosis research, 2013-07, Vol.132 (1), p.e48-e53

2013

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The presence of γ′ chain impairs fibrin polymerization

Thrombosis research, 2009-07, Vol.124 (3), p.356-363

2009

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Fibrinogen variant BβD432A has normal polymerization but does not bind knob “B”

Blood, 2009-04, Vol.113 (18), p.4425-4430

2009

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A novel transgenic mouse model of hyperfibrinogenemia

Thrombosis and haemostasis, 2001-08, Vol.86 (2), p.511-516

2001

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The Assembly of Nonadhesive Fibrinogen Matrices Depends on the αC Regions of the Fibrinogen Molecule

The Journal of biological chemistry, 2012-12, Vol.287 (50), p.41979-41990

2012

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In vitro expression demonstrates impaired secretion of the γAsn319, Asp320 deletion variant fibrinogen

Thrombosis and haemostasis, 2005-07, Vol.94 (7), p.53-59

2005

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Agnes Henschen-Edman, M.D., Ph.D. April 1, 1935 to October 23, 2011

THROMBOSIS RESEARCH, 2012-09, Vol.130 (3), p.568-569

2012

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Impaired Protofibril Formation in Fibrinogen γN308K Is Due to Altered D:D and “A:a” Interactions

Biochemistry (Easton), 2009-09, Vol.48 (36), p.8656-8663

2009

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Unique Pathway of Thrombin-induced Platelet Aggregation Mediated by Glycoprotein Ib

The Journal of biological chemistry, 2001-06, Vol.276 (24), p.21173-21183

2001

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An engineered fibrinogen variant AαQ328,366P does not polymerise normally, but retains the ability to form α cross-links

Thrombosis and haemostasis, 2013-02, Vol.109 (2), p.199-206

2013

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Molecular mechanisms affecting fibrin structure and stability

The molecular origins of the mechanical properties of fibrin

Submillisecond Elastic Recoil Reveals Molecular Origins of Fibrin Fiber Mechanics

Stiffening of Individual Fibrin Fibers Equitably Distributes Strain and Strengthens Networks

Fibrinogen and fibrin: scaffold proteins in hemostasis

Factor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin α-chain crosslinking

Influence of Glutathione and its Derivatives on Fibrin Polymerization

Coming full circle with factor XIII

The isolation of fibrinogen monomer dramatically influences fibrin polymerization

Mouse models in coagulation

Substitution of the Human αC Region with the Analogous Chicken Domain Generates a Fibrinogen with Severely Impaired Lateral Aggregation: Fibrin Monomers Assemble into Protofibrils but Protofibrils Do Not Assemble into Fibers

Calcium-Binding Site β2, Adjacent to the “b” Polymerization Site, Modulates Lateral Aggregation of Protofibrils during Fibrin Polymerization

Does Topology Drive Fiber Polymerization?

Evidence that αC Region Is Origin of Low Modulus, High Extensibility, and Strain Stiffening in Fibrin Fibers

Dynamic Regulation of Fibrinogen: Integrin αIIbβ3 Binding

Hydrodynamic characterization of recombinant human fibrinogen species

The presence of γ′ chain impairs fibrin polymerization

Fibrinogen variant BβD432A has normal polymerization but does not bind knob “B”

A novel transgenic mouse model of hyperfibrinogenemia

The Assembly of Nonadhesive Fibrinogen Matrices Depends on the αC Regions of the Fibrinogen Molecule

In vitro expression demonstrates impaired secretion of the γAsn319, Asp320 deletion variant fibrinogen

Agnes Henschen-Edman, M.D., Ph.D. April 1, 1935 to October 23, 2011

Impaired Protofibril Formation in Fibrinogen γN308K Is Due to Altered D:D and “A:a” Interactions

Unique Pathway of Thrombin-induced Platelet Aggregation Mediated by Glycoprotein Ib

An engineered fibrinogen variant AαQ328,366P does not polymerise normally, but retains the ability to form α cross-links

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