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Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells

Nature communications, 2015-08, Vol.6 (1), p.8036-8036, Article 8036

2015

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TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress

EMBO reports, 2019-01, Vol.20 (1), p.n/a

2019

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A Proteomic Characterization of Factors Enriched at Nascent DNA Molecules

Cell reports (Cambridge), 2013-04, Vol.3 (4), p.1105-1116

2013

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Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors

Nature structural & molecular biology, 2011-12, Vol.18 (12), p.1331

2011

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Cyclin-Dependent Kinase Inhibitor p21 Controls Adult Neural Stem Cell Expansion by Regulating Sox2 Gene Expression

Cell stem cell, 2013-01, Vol.12 (1), p.88-100

2013

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Loss of PICH Results in Chromosomal Instability, p53 Activation, and Embryonic Lethality

Cell reports (Cambridge), 2018-09, Vol.24 (12), p.3274-3284

2018

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ATRX-Deficient High-Grade Glioma Cells Exhibit Increased Sensitivity to RTK and PDGFR Inhibitors

Cancers, 2022-03, Vol.14 (7), p.1790

2022

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PICH deficiency limits the progression of MYC-induced B-cell lymphoma

Blood cancer journal (New York), 2024-01, Vol.14 (1), p.16-16, Article 16

2024

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USP7 is a SUMO deubiquitinase essential for DNA replication

Nature structural & molecular biology, 2016-04, Vol.23 (4), p.270

2016

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Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability

Nucleic acids research, 2019-09, Vol.47 (15), p.8004

2019

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An extra allele of Chk1 limits oncogene-induced replicative stress and promotes transformation

The Journal of experimental medicine, 2012-03, Vol.209 (3), p.455-461

2012

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A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development

Molecular and cellular biology, 2015-09, Vol.35 (17), p.2910-2917

2015

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Efficacy of ATR inhibitors as single agents in Ewing sarcoma

Oncotarget, 2016-09, Vol.7 (37), p.58759-58767

2016

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Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice

Genes & development, 2015-04, Vol.29 (7), p.690-695

2015

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Supraphysiological protection from replication stress does not extend mammalian lifespan

Aging (Albany, NY.), 2020-04, Vol.12 (7), p.5612-5624

2020

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BRCA1 Functions Independently of Homologous Recombination in DNA Interstrand Crosslink Repair

Molecular cell, 2012-04, Vol.46 (2), p.125-135

2012

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Modeling the study of DNA damage responses in mice

Methods in molecular biology (Clifton, N.J.), 2015, Vol.1267, p.413

2015

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A simple DNA recombination screening method by RT-PCR as an alternative to Southern blot

Transgenic research, 2017-06, Vol.26 (3), p.429-434

2017

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INK4a/ARF limits the expansion of cells suffering from replication stress

Cell cycle (Georgetown, Tex.), 2013-06, Vol.12 (12), p.1948-1954

2013

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The ATR barrier to replication-born DNA damage

DNA repair, 2010-12, Vol.9 (12), p.1249-1255

2010

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Fos-dependent induction of Chk1 protects osteoblasts from replication stress

Cell cycle (Georgetown, Tex.), 2014-06, Vol.13 (12), p.1980-1986

2014

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Opposite sexual dimorphism of 3,4-dihydroxyphenylalanine decarboxylase in the kidney and small intestine of mice

Journal of endocrinology, 2008-03, Vol.196 (3), p.615-624

2008

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Structural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2

FEBS open bio, 2014-01, Vol.4 (1), p.510-521

2014

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Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells

TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress

A Proteomic Characterization of Factors Enriched at Nascent DNA Molecules

Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors

Cyclin-Dependent Kinase Inhibitor p21 Controls Adult Neural Stem Cell Expansion by Regulating Sox2 Gene Expression

Loss of PICH Results in Chromosomal Instability, p53 Activation, and Embryonic Lethality

ATRX-Deficient High-Grade Glioma Cells Exhibit Increased Sensitivity to RTK and PDGFR Inhibitors

PICH deficiency limits the progression of MYC-induced B-cell lymphoma

USP7 is a SUMO deubiquitinase essential for DNA replication

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability

An extra allele of Chk1 limits oncogene-induced replicative stress and promotes transformation

A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development

DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas

Efficacy of ATR inhibitors as single agents in Ewing sarcoma

Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice

Supraphysiological protection from replication stress does not extend mammalian lifespan

BRCA1 Functions Independently of Homologous Recombination in DNA Interstrand Crosslink Repair

Modeling the study of DNA damage responses in mice

DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas

A simple DNA recombination screening method by RT-PCR as an alternative to Southern blot

INK4a/ARF limits the expansion of cells suffering from replication stress

The ATR barrier to replication-born DNA damage

Fos-dependent induction of Chk1 protects osteoblasts from replication stress

Opposite sexual dimorphism of 3,4-dihydroxyphenylalanine decarboxylase in the kidney and small intestine of mice

Structural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2

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