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A circuit for secretion‐coupled cellular autonomy in multicellular eukaryotic cells

Molecular systems biology, 2023-04, Vol.19 (4), p.e11127-n/a

2023

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Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin

Molecular biology of the cell, 2014-11, Vol.25 (22), p.3654-3671

2014

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Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling

eLife, 2015-06, Vol.4, p.e07091-e07091

2015

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Cyclin-dependent kinase 5 activates guanine nucleotide exchange factor GIV/Girdin to orchestrate migration–proliferation dichotomy

Proceedings of the National Academy of Sciences - PNAS, 2015-09, Vol.112 (35), p.E4874-E4883

2015

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VRK1 interacts with p53 forming a basal complex that is activated by UV-induced DNA damage

FEBS letters, 2014-03, Vol.588 (5), p.692-700

2014

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Focal adhesions are foci for tyrosine-based signal transduction via GIV/Girdin and G proteins

Molecular biology of the cell, 2015-12, Vol.26 (24), p.4313-4324

2015

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GIV/Girdin, a non-receptor modulator for Gαi/s, regulates spatiotemporal signaling during sperm capacitation and is required for male fertility

eLife, 2021-08, Vol.10

2021

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Therapeutic effects of cell-permeant peptides that activate G proteins downstream of growth factors

Proceedings of the National Academy of Sciences - PNAS, 2015-05, Vol.112 (20), p.E2602-E2610

2015

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GIV•Kindlin Interaction Is Required for Kindlin-Mediated Integrin Recognition and Activation

iScience, 2020-06, Vol.23 (6), p.101209-101209, Article 101209

2020

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Proteomics Identification of Nuclear Ran GTPase as an Inhibitor of Human VRK1 and VRK2 (Vaccinia-related Kinase) Activities

Molecular & cellular proteomics, 2008-11, Vol.7 (11), p.2199-2214

2008

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Identification of a dominant epitope in human vaccinia-related kinase 1 (VRK1) and detection of different intracellular subpopulations

Archives of biochemistry and biophysics, 2007-09, Vol.465 (1), p.219-226

2007

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Identification of Noncanonical Wnt Receptors Required for Wnt-3a-Induced Early Differentiation of Human Neural Stem Cells

Molecular neurobiology, 2017-10, Vol.54 (8), p.6213-6224

2017

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Human VRK1 is an early response gene and its loss causes a block in cell cycle progression

PloS one, 2008-02, Vol.3 (2), p.e1642-e1642

2008

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Receptor tyrosine kinases activate heterotrimeric G proteins via phosphorylation within the interdomain cleft of Gαi

Proceedings of the National Academy of Sciences - PNAS, 2020-11, Vol.117 (46), p.28763-28774

2020

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The effect of virtual reality versus standard‐of‐care treatment on pain perception during paediatric vaccination: A randomised controlled trial

Journal of clinical nursing, 2024-06

2024

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Protein kinase C-theta (PKCθ) phosphorylates and inhibits the guanine exchange factor, GIV/Girdin

Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (14), p.5510-5515

2013

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The short and long-term effects of aerobic, strength, or mixed exercise programs on schizophrenia symptomatology

Scientific reports, 2021-12, Vol.11 (1), p.24300-24300, Article 24300

2021

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GIV/girdin binds exocyst subunit-Exo70 and regulates exocytosis of GLUT4 storage vesicles

Biochemical and biophysical research communications, 2015-12, Vol.468 (1-2), p.287-293

2015

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GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis

Nature communications, 2014-07, Vol.5 (1), p.4451, Article 4451

2014

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GIV/Girdin, a non-receptor modulator for G[alpha]i/s, regulates spatiotemporal signaling during sperm capacitation and is required for male fertility

eLife, 2021-08, Vol.10

2021

Volltextzugriff (PDF)

Convergence of Wnt, Growth Factor and Trimeric G‐protein Signals on the Signaling Scaffold Daple

The FASEB journal, 2018-04, Vol.32 (S1), p.533.37-533.37

2018

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Activation of Gαi at the Golgi by GIV/Girdin imposes finiteness in Arf1 signaling

Developmental cell, 2015-04, Vol.33 (2), p.189-203

2015

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Activation of G proteins by GIV-GEF is a pivot point for insulin resistance and sensitivity

Molecular biology of the cell, 2015-11, Vol.26 (23), p.4209-4223

2015

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Biochemical, Biophysical and Cellular Techniques to Study the Guanine Nucleotide Exchange Factor, GIV/Girdin

Current protocols in chemical biology, 2016-12, Vol.8 (4), p.265-298

2016

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GIV/Girdin activates Gαi and inhibits Gαs via the same motif

Proceedings of the National Academy of Sciences - PNAS, 2016-09, Vol.113 (39), p.E5721-E5730

2016

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A circuit for secretion‐coupled cellular autonomy in multicellular eukaryotic cells

Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin

Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling

Cyclin-dependent kinase 5 activates guanine nucleotide exchange factor GIV/Girdin to orchestrate migration–proliferation dichotomy

VRK1 interacts with p53 forming a basal complex that is activated by UV-induced DNA damage

Focal adhesions are foci for tyrosine-based signal transduction via GIV/Girdin and G proteins

GIV/Girdin, a non-receptor modulator for Gαi/s, regulates spatiotemporal signaling during sperm capacitation and is required for male fertility

Therapeutic effects of cell-permeant peptides that activate G proteins downstream of growth factors

GIV•Kindlin Interaction Is Required for Kindlin-Mediated Integrin Recognition and Activation

Proteomics Identification of Nuclear Ran GTPase as an Inhibitor of Human VRK1 and VRK2 (Vaccinia-related Kinase) Activities

Identification of a dominant epitope in human vaccinia-related kinase 1 (VRK1) and detection of different intracellular subpopulations

Identification of Noncanonical Wnt Receptors Required for Wnt-3a-Induced Early Differentiation of Human Neural Stem Cells

Human VRK1 is an early response gene and its loss causes a block in cell cycle progression

Receptor tyrosine kinases activate heterotrimeric G proteins via phosphorylation within the interdomain cleft of Gαi

The effect of virtual reality versus standard‐of‐care treatment on pain perception during paediatric vaccination: A randomised controlled trial

Protein kinase C-theta (PKCθ) phosphorylates and inhibits the guanine exchange factor, GIV/Girdin

The short and long-term effects of aerobic, strength, or mixed exercise programs on schizophrenia symptomatology

GIV/girdin binds exocyst subunit-Exo70 and regulates exocytosis of GLUT4 storage vesicles

GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis

GIV/Girdin, a non-receptor modulator for G[alpha]i/s, regulates spatiotemporal signaling during sperm capacitation and is required for male fertility

Convergence of Wnt, Growth Factor and Trimeric G‐protein Signals on the Signaling Scaffold Daple

Activation of Gαi at the Golgi by GIV/Girdin imposes finiteness in Arf1 signaling

Activation of G proteins by GIV-GEF is a pivot point for insulin resistance and sensitivity

Biochemical, Biophysical and Cellular Techniques to Study the Guanine Nucleotide Exchange Factor, GIV/Girdin

GIV/Girdin activates Gαi and inhibits Gαs via the same motif

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