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Adenosine Receptors in Neurodegenerative Diseases

1, 2017

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Maternal separation impairs long term-potentiation in CA1-CA3 synapses and hippocampal-dependent memory in old rats

Neurobiology of aging, 2014-07, Vol.35 (7), p.1680-1685

2014

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Adenosine and related drugs in brain diseases: present and future in clinical trials

Current topics in medicinal chemistry, 2011-04, Vol.11 (8), p.1087

2011

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Adenosine A2A receptors and brain injury: broad spectrum of neuroprotection, multifaceted actions and "fine tuning" modulation

Progress in neurobiology, 2007-12, Vol.83 (5), p.310-331

2007

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Enhancement of LTP in Aged Rats is Dependent on Endogenous BDNF

Neuropsychopharmacology, 2011-08, Vol.36 (9), p.1823-1836

2011

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Beneficial Effect of a Selective Adenosine A2A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease

Frontiers in molecular neuroscience, 2018-07, Vol.11, p.235-235

2018

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The Amyloid Precursor Protein C-Terminal Domain Alters CA1 Neuron Firing, Modifying Hippocampus Oscillations and Impairing Spatial Memory Encoding

Cell reports (Cambridge), 2019-10, Vol.29 (2), p.317-331.e5

2019

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Escitalopram improves memory deficits induced by maternal separation in the rat

European journal of pharmacology, 2012-11, Vol.695 (1-3), p.71-75

2012

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Mutant A53T α-Synuclein Improves Rotarod Performance Before Motor Deficits and Affects Metabolic Pathways

Neuromolecular medicine, 2017-03, Vol.19 (1), p.113-121

2017

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Neuroprotection afforded by adenosine A2A receptor blockade is modulated by corticotrophin-releasing factor (CRF) in glutamate injured cortical neurons

Journal of neurochemistry, 2012-12, Vol.123 (6), p.1030-1040

2012

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Impact of in vivo chronic blockade of adenosine A2A receptors on the BDNF-mediated facilitation of LTP

Neuropharmacology, 2014-08, Vol.83, p.99-106

2014

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Overexpression of Adenosine A2A Receptors in Rats: Effects on Depression, Locomotion, and Anxiety

Frontiers in psychiatry, 2014-06, Vol.5, p.67-67

2014

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Design, synthesis and evaluation of 2-aryl benzoxazoles as promising hit for the A2A receptor

Journal of enzyme inhibition and medicinal chemistry, 2017-12, Vol.32 (1), p.850-864

2017

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Stabilizing synapses

Science (American Association for the Advancement of Science), 2021-11, Vol.374 (6568), p.684-685

2021

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Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation

The Journal of neuroscience, 2012-08, Vol.32 (34), p.11750-11762

2012

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Exacerbation of C1q dysregulation, synaptic loss and memory deficits in tau pathology linked to neuronal adenosine A2A receptor

Brain (London, England : 1878), 2019-11, Vol.142 (11), p.3636-3654

2019

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The impact of daylight‐saving time (DST) on patients with delayed sleep‐wake phase disorder (DSWPD)

Journal of pineal research, 2023-05, Vol.74 (4), p.e12867-n/a

2023

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Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies

Brain (London, England : 1878), 2017-05, Vol.140 (5), p.1399-1419

2017

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Prolactin-induced neuroprotection against glutamate excitotoxicity is mediated by the reduction of [Ca2+]i overload and NF-κB activation

PloS one, 2017-05, Vol.12 (5), p.e0176910-e0176910

2017

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Sensing α‐Synuclein From the Outside via the Prion Protein: Implications for Neurodegeneration

Movement disorders, 2018-11, Vol.33 (11), p.1675-1684

2018

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Inhibition of NMDA Receptors Prevents the Loss of BDNF Function Induced by Amyloid β

Frontiers in pharmacology, 2018-04, Vol.9, p.237-237

2018

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Age‐dependent NMDA receptor function is regulated by the amyloid precursor protein

Aging cell, 2023-03, Vol.22 (3), p.e13778-n/a

2023

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S327 phosphorylation of the presynaptic protein SEPTIN5 increases in the early stages of neurofibrillary pathology and alters the functionality of SEPTIN5

Neurobiology of disease, 2022-02, Vol.163, p.105603-105603, Article 105603

2022

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The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function

Scientific reports, 2016-08, Vol.6 (1), p.31493-31493, Article 31493

2016

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Validation of the Portuguese Variant of the Munich Chronotype Questionnaire (MCTQ PT )

Frontiers in physiology, 2020-07, Vol.11, p.795-795

2020

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Adenosine Receptors in Neurodegenerative Diseases

Maternal separation impairs long term-potentiation in CA1-CA3 synapses and hippocampal-dependent memory in old rats

Adenosine and related drugs in brain diseases: present and future in clinical trials

Adenosine A2A receptors and brain injury: broad spectrum of neuroprotection, multifaceted actions and "fine tuning" modulation

Enhancement of LTP in Aged Rats is Dependent on Endogenous BDNF

Beneficial Effect of a Selective Adenosine A2A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease

The Amyloid Precursor Protein C-Terminal Domain Alters CA1 Neuron Firing, Modifying Hippocampus Oscillations and Impairing Spatial Memory Encoding

Escitalopram improves memory deficits induced by maternal separation in the rat

Mutant A53T α-Synuclein Improves Rotarod Performance Before Motor Deficits and Affects Metabolic Pathways

Neuroprotection afforded by adenosine A2A receptor blockade is modulated by corticotrophin-releasing factor (CRF) in glutamate injured cortical neurons

Impact of in vivo chronic blockade of adenosine A2A receptors on the BDNF-mediated facilitation of LTP

Overexpression of Adenosine A2A Receptors in Rats: Effects on Depression, Locomotion, and Anxiety

Design, synthesis and evaluation of 2-aryl benzoxazoles as promising hit for the A2A receptor

Stabilizing synapses

Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation

Exacerbation of C1q dysregulation, synaptic loss and memory deficits in tau pathology linked to neuronal adenosine A2A receptor

The impact of daylight‐saving time (DST) on patients with delayed sleep‐wake phase disorder (DSWPD)

Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies

Prolactin-induced neuroprotection against glutamate excitotoxicity is mediated by the reduction of [Ca2+]i overload and NF-κB activation

Sensing α‐Synuclein From the Outside via the Prion Protein: Implications for Neurodegeneration

Inhibition of NMDA Receptors Prevents the Loss of BDNF Function Induced by Amyloid β

Age‐dependent NMDA receptor function is regulated by the amyloid precursor protein

S327 phosphorylation of the presynaptic protein SEPTIN5 increases in the early stages of neurofibrillary pathology and alters the functionality of SEPTIN5

The caffeine-binding adenosine A2A receptor induces age-like HPA-axis dysfunction by targeting glucocorticoid receptor function

Validation of the Portuguese Variant of the Munich Chronotype Questionnaire (MCTQ PT )

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