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The auxiliary subunit KCNE1 regulates KCNQ1 channel response to sustained calcium-dependent PKC activation

PloS one, 2020-08, Vol.15 (8), p.e0237591-e0237591

2020

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Molecular Basis of Decreased Kir4.1 Function in SeSAME/EAST Syndrome

Journal of the American Society of Nephrology, 2010-12, Vol.21 (12), p.2117-2129

2010

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Membrane pools of phosphatidylinositol-4-phosphate regulate KCNQ1/KCNE1 membrane expression

Communications biology, 2021-12, Vol.4 (1), p.1392-1392, Article 1392

2021

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Genetic variant annotation scores in congenital long QT syndrome

Annals of noninvasive electrocardiology, 2023-09, Vol.28 (5), p.e13080-n/a

2023

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PIP2 hydrolysis underlies agonist-induced inhibition and regulates voltage gating of two-pore domain K+ channels

The Journal of physiology, 2005-04, Vol.564 (1), p.117-129

2005

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Adrenergic Signaling Controls RGK-Dependent Trafficking of Cardiac Voltage-Gated L-Type Ca2+ Channels Through PKD1

Circulation research, 2012-01, Vol.110 (1), p.59-70

2012

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Trigger-specific risk factors and response to therapy in long QT syndrome type 2

Heart rhythm, 2010-12, Vol.7 (12), p.1797-1805

2010

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Trigger-specific ion-channel mechanisms, risk factors, and response to therapy in type 1 long QT syndrome

Heart rhythm, 2012, Vol.9 (1), p.49-56

2012

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Stop-codon and C-terminal nonsense mutations are associated with a lower risk of cardiac events in patients with long QT syndrome type 1

Heart rhythm, 2016, Vol.13 (1), p.122-131

2016

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Risk of life-threatening cardiac events among patients with long QT syndrome and multiple mutations

Heart rhythm, 2013-03, Vol.10 (3), p.378-382

2013

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Statin-specific inhibition of Rab-GTPase regulates cPKC-mediated IKs internalization

Scientific reports, 2019-11, Vol.9 (1), p.17747-12, Article 17747

2019

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Fluvastatin inhibits Rab5-mediated IKs internalization caused by chronic Ca2+-dependent PKC activation

Journal of molecular and cellular cardiology, 2019-04, Vol.129, p.314-325

2019

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Specificity of Activation by Phosphoinositides Determines Lipid Regulation of Kir Channels

Proceedings of the National Academy of Sciences - PNAS, 2003-01, Vol.100 (2), p.745-750

2003

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Short and long QT syndromes: does QT length really matter?

Journal of electrocardiology, 2010-09, Vol.43 (5), p.396-399

2010

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Use of mutant-specific ion channel characteristics for risk stratification of long QT syndrome patients

Science translational medicine, 2011-03, Vol.3 (76), p.76ra28

2011

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Small Molecule Disruption of Gβγ Signaling Inhibits the Progression of Heart Failure

Circulation research, 2010-08, Vol.107 (4), p.532-539

2010

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PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain

Nature neuroscience, 2005-05, Vol.8 (5), p.626-634

2005

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Mutations in Cytoplasmic Loops of the KCNQ1 Channel and the Risk of Life-Threatening Events: Implications for Mutation-Specific Response to β-Blocker Therapy in Type 1 Long-QT Syndrome

Circulation (New York, N.Y.), 2012-04, Vol.125 (16), p.1988-1996

2012

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Mutations in Conserved Amino Acids in the KCNQ1 Channel and Risk of Cardiac Events in Type-1 Long-QT Syndrome

Journal of cardiovascular electrophysiology, 2009-08, Vol.20 (8), p.859-865

2009

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In Silico Cardiac Risk Assessment in Patients With Long QT Syndrome

Journal of the American College of Cardiology, 2012-11, Vol.60 (21), p.2182-2191

2012

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Isoform-specific dynamic translocation of PKC by α1-adrenoceptor stimulation in live cells

Biochemical and biophysical research communications, 2015-09, Vol.465 (3), p.464-470

2015

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Impaired IKs channel activation by Ca(2+)-dependent PKC shows correlation with emotion/arousal-triggered events in LQT1

Journal of molecular and cellular cardiology, 2015-02, Vol.79, p.203-211

2015

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The auxiliary subunit KCNE1 regulates KCNQ1 channel response to sustained calcium-dependent PKC activation

Molecular Basis of Decreased Kir4.1 Function in SeSAME/EAST Syndrome

Membrane pools of phosphatidylinositol-4-phosphate regulate KCNQ1/KCNE1 membrane expression

Genetic variant annotation scores in congenital long QT syndrome

PIP2 hydrolysis underlies agonist-induced inhibition and regulates voltage gating of two-pore domain K+ channels

Adrenergic Signaling Controls RGK-Dependent Trafficking of Cardiac Voltage-Gated L-Type Ca2+ Channels Through PKD1

Mutation and gender-specific risk in type 2 long QT syndrome: Implications for risk stratification for life-threatening cardiac events in patients with long QT syndrome

Trigger-specific risk factors and response to therapy in long QT syndrome type 2

Trigger-specific ion-channel mechanisms, risk factors, and response to therapy in type 1 long QT syndrome

Stop-codon and C-terminal nonsense mutations are associated with a lower risk of cardiac events in patients with long QT syndrome type 1

Risk of life-threatening cardiac events among patients with long QT syndrome and multiple mutations

Statin-specific inhibition of Rab-GTPase regulates cPKC-mediated IKs internalization

Fluvastatin inhibits Rab5-mediated IKs internalization caused by chronic Ca2+-dependent PKC activation

Specificity of Activation by Phosphoinositides Determines Lipid Regulation of Kir Channels

Short and long QT syndromes: does QT length really matter?

Use of mutant-specific ion channel characteristics for risk stratification of long QT syndrome patients

Prognostic implications of mutation-specific QTc standard deviation in congenital long QT syndrome

Small Molecule Disruption of Gβγ Signaling Inhibits the Progression of Heart Failure

PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain

Mutations in Cytoplasmic Loops of the KCNQ1 Channel and the Risk of Life-Threatening Events: Implications for Mutation-Specific Response to β-Blocker Therapy in Type 1 Long-QT Syndrome

Risk for Life-Threatening Cardiac Events in Patients With Genotype-Confirmed Long-QT Syndrome and Normal-Range Corrected QT Intervals

Mutations in Conserved Amino Acids in the KCNQ1 Channel and Risk of Cardiac Events in Type-1 Long-QT Syndrome

In Silico Cardiac Risk Assessment in Patients With Long QT Syndrome

Isoform-specific dynamic translocation of PKC by α1-adrenoceptor stimulation in live cells

Impaired IKs channel activation by Ca(2+)-dependent PKC shows correlation with emotion/arousal-triggered events in LQT1

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