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Inflammasomes in neuroinflammatory and neurodegenerative diseases

EMBO molecular medicine, 2019-06, Vol.11 (6), p.n/a

2019

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The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation

Immunity (Cambridge, Mass.), 2011-10, Vol.35 (4), p.572-582

2011

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Microglia in Central Nervous System Inflammation and Multiple Sclerosis Pathology

Trends in molecular medicine, 2019-02, Vol.25 (2), p.112-123

2019

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Attenuation of cGAS‐STING signaling is mediated by a p62/SQSTM1‐dependent autophagy pathway activated by TBK1

The EMBO journal, 2018-04, Vol.37 (8), p.n/a

2018

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CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair

Blood, 2012-07, Vol.120 (3), p.613-625

2012

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OTULIN in NF-κB signaling, cell death, and disease

Trends in immunology, 2021-07, Vol.42 (7), p.590-603

2021

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Genetic relationships between A20/TNFAIP3, chronic inflammation and autoimmune disease

Biochemical Society transactions, 2011-08, Vol.39 (4), p.1086-1091

2011

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FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation

Nature (London), 2011-09, Vol.477 (7364), p.330-334

2011

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A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain

Nature cell biology, 2019-06, Vol.21 (6), p.731-742

2019

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The Ubiquitin-Editing Protein A20 Prevents Dendritic Cell Activation, Recognition of Apoptotic Cells, and Systemic Autoimmunity

Immunity (Cambridge, Mass.), 2011-07, Vol.35 (1), p.82-96

2011

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Endothelial CCR2 Signaling Induced by Colon Carcinoma Cells Enables Extravasation via the JAK2-Stat5 and p38MAPK Pathway

Cancer cell, 2012-07, Vol.22 (1), p.91-105

2012

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MicroRNA let-7 Modulates the Immune Response to Mycobacterium tuberculosis Infection via Control of A20, an Inhibitor of the NF-κB Pathway

Cell host & microbe, 2015-03, Vol.17 (3), p.345-356

2015

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Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities

Nature immunology, 2020-04, Vol.21 (4), p.381-387

2020

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OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity

Nature communications, 2021-10, Vol.12 (1), p.5913-5913, Article 5913

2021

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Optineurin deficiency in mice is associated with increased sensitivity to Salmonella but does not affect proinflammatory NF‐κB signaling

European journal of immunology, 2016-04, Vol.46 (4), p.971-980

2016

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A20 (Tnfaip3) deficiency in myeloid cells protects against influenza A virus infection

PLoS pathogens, 2012-03, Vol.8 (3), p.e1002570-e1002570

2012

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A20 and Cell Death-driven Inflammation

Trends in immunology, 2020-05, Vol.41 (5), p.421-435

2020

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Toxic proteins released from mitochondria in cell death

Oncogene, 2004-04, Vol.23 (16), p.2861-2874

2004

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Cellular Functions of Optineurin in Health and Disease

Trends in immunology, 2016-09, Vol.37 (9), p.621-633

2016

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A20 controls RANK‐dependent osteoclast formation and bone physiology

EMBO reports, 2022-12, Vol.23 (12), p.e55233-n/a

2022

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Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution

Nature (London), 2019-02, Vol.566 (7744), p.388-392

2019

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A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

Nature genetics, 2011-09, Vol.43 (9), p.908-912

2011

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Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis

Nature communications, 2019-04, Vol.10 (1), p.1834-1834, Article 1834

2019

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A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms

Cell death & disease, 2019-09, Vol.10 (10), p.692, Article 692

2019

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Tnfaip3 expression in pulmonary conventional type 1 Langerin‐expressing dendritic cells regulates T helper 2‐mediated airway inflammation in mice

Allergy (Copenhagen), 2020-10, Vol.75 (10), p.2587-2598

2020

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Inflammasomes in neuroinflammatory and neurodegenerative diseases

The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation

Microglia in Central Nervous System Inflammation and Multiple Sclerosis Pathology

Attenuation of cGAS‐STING signaling is mediated by a p62/SQSTM1‐dependent autophagy pathway activated by TBK1

CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair

OTULIN in NF-κB signaling, cell death, and disease

Genetic relationships between A20/TNFAIP3, chronic inflammation and autoimmune disease

FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation

A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain

The Ubiquitin-Editing Protein A20 Prevents Dendritic Cell Activation, Recognition of Apoptotic Cells, and Systemic Autoimmunity

Endothelial CCR2 Signaling Induced by Colon Carcinoma Cells Enables Extravasation via the JAK2-Stat5 and p38MAPK Pathway

MicroRNA let-7 Modulates the Immune Response to Mycobacterium tuberculosis Infection via Control of A20, an Inhibitor of the NF-κB Pathway

Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities

OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity

Optineurin deficiency in mice is associated with increased sensitivity to Salmonella but does not affect proinflammatory NF‐κB signaling

A20 (Tnfaip3) deficiency in myeloid cells protects against influenza A virus infection

A20 and Cell Death-driven Inflammation

Toxic proteins released from mitochondria in cell death

Cellular Functions of Optineurin in Health and Disease

A20 controls RANK‐dependent osteoclast formation and bone physiology

Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis

A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms

Tnfaip3 expression in pulmonary conventional type 1 Langerin‐expressing dendritic cells regulates T helper 2‐mediated airway inflammation in mice

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