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Alkylphosphocholine analogs for broad-spectrum cancer imaging and therapy

Science translational medicine, 2014-06, Vol.6 (240), p.240ra75

2014

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Effect of Polar Head Group Modifications on the Tumor Retention of Phospholipid Ether Analogs: Role of the Quaternary Nitrogen

Pharmaceutics, 2023-01, Vol.15 (1), p.171

2023

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Quantification of CLR1401, a novel alkylphosphocholine anticancer agent, in rat plasma by hydrophilic interaction liquid chromatography–tandem mass spectrometric detection

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010-06, Vol.878 (19), p.1513-1518

2010

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Synthesis and Structure−Activity Relationship Effects on the Tumor Avidity of Radioiodinated Phospholipid Ether Analogues

Journal of medicinal chemistry, 2006-04, Vol.49 (7), p.2155-2165

2006

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Methoxypoly(ethylene glycol)-conjugated carboxypeptidase A for solid tumor targeting. Part II: Pharmacokinetics and biodistribution in normal and tumor-bearing rodents

Journal of controlled release, 2005-05, Vol.104 (1), p.155-166

2005

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Polyiodinated Triglyceride Lipid Emulsions for Use as Hepatoselective Contrast Agents in CT: Effects of Physicochemical Properties on Biodistribution and Imaging Profiles

Investigative radiology, 2000-03, Vol.35 (3), p.158-169

2000

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A Surface-Modified Chylomicron Remnant-like Emulsion for Percutaneous Computed Tomography Lymphography: Synthesis and Preliminary Imaging Findings

Investigative radiology, 2002-04, Vol.37 (4), p.232-239

2002

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Hepatobiliary Imaging Using a Novel Hepatocyte-Selective CT Contrast Agent

Academic radiology, 2002, Vol.9 (1), p.S194-S199

2002

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Lipid-based blood-pool CT imaging of the liver

Academic radiology, 1998-04, Vol.5, p.S16-S19

1998

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Polyiodinated Triglyceride Analogs as Potential Computed Tomography Imaging Agents for the Liver

Journal of medicinal chemistry, 1995-02, Vol.38 (4), p.636-646

1995

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Percutaneous CT Lymphography Using a New Polyiodinated Biomimetic Microemulsion

Academic radiology, 2002, Vol.9 (1), p.S191-S193

2002

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Imaging Efficacy of a Hepatocyte-Selective Polyiodinated Triglyceride (DHOG-LE) for Contrast–enhanced CT

Academic radiology, 2002, Vol.9 (1), p.S200-S204

2002

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Abstract 3495: The novel phospholipid ether analog CLR1404 decreases glioblastoma stem cell proliferation, suppresses GBM growth, and improves survival

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.3495-3495

2012

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Computed tomography scanning of morris hepatomas with liver-specific polyiodinated triglycerides

Academic radiology, 1996-05, Vol.3 (5), p.412-417

1996

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Abberations in Phospholipase D Activity‐A Pharmacological Target for Cancer Detection

The FASEB journal, 2006-03, Vol.20 (4), p.A488-A488

2006

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Biographical Sketch: Dr. Raymond E. Counsell

American journal of therapeutics, 2001-09, Vol.8 (5), p.319

Longino, Marc A.

2001

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Methoxypoly(ethylene glycol)-conjugated carboxypeptidase A for solid tumor targeting

Journal of controlled release, 2005-05, Vol.104 (1), p.155-166

2005

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Combined hepatocyte-selective and blood-pool contrast agents for the CT detection of experimental liver tumors in rabbits

Radiology, 2000-09, Vol.216 (3), p.865-871

2000

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Biotinylated granulocyte/macrophage colony-stimulating factor analogs: effect of linkage chemistry on activity and binding

Bioconjugate chemistry, 1991-11, Vol.2 (6), p.466-474

1991

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Potential tumor- or organ-imaging agents. 26. Polyiodinated 2-substituted triacylglycerols as hepatographic agents

Journal of medicinal chemistry, 1986-09, Vol.29 (9), p.1674-1682

1986

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Potential tumor- or organ-imaging agents. 27. Polyiodinated 1,3-disubstituted and 1,2,3-trisubstituted triacylglycerols

Journal of medicinal chemistry, 1986-12, Vol.29 (12), p.2457-2465

1986

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Physicochemical Characterization of a Synthetic Lipid Emulsion for Hepatocyte-Selective Delivery of Lipophilic Compounds: Application to Polyiodinated Triglycerides as Contrast Agents for Computed Tomography

Journal of pharmaceutical sciences, 1996-09, Vol.85 (9), p.908-914

1996

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Imaging efficacy of a hepatocyte-selective polyiodinated triglyceride for contrast-enhanced computed tomography

American journal of therapeutics, 2001-09, Vol.8 (5), p.359-365

2001

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Computed tomography scanning of hepatic tumors with polyiodinated triglycerides

Academic radiology, 1996-08, Vol.3, p.S229-S231

1996

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Lipoprotein Incorporation Enhances Radioiodinated Cholesteryl Ester Uptake into Steroid Hormone-Secreting Tissues

The Journal of nuclear medicine (1978), 1989-06, Vol.30 (6), p.1088-1094

1989

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Alkylphosphocholine analogs for broad-spectrum cancer imaging and therapy

Effect of Polar Head Group Modifications on the Tumor Retention of Phospholipid Ether Analogs: Role of the Quaternary Nitrogen

Quantification of CLR1401, a novel alkylphosphocholine anticancer agent, in rat plasma by hydrophilic interaction liquid chromatography–tandem mass spectrometric detection

Synthesis and Structure−Activity Relationship Effects on the Tumor Avidity of Radioiodinated Phospholipid Ether Analogues

Methoxypoly(ethylene glycol)-conjugated carboxypeptidase A for solid tumor targeting. Part II: Pharmacokinetics and biodistribution in normal and tumor-bearing rodents

Polyiodinated Triglyceride Lipid Emulsions for Use as Hepatoselective Contrast Agents in CT: Effects of Physicochemical Properties on Biodistribution and Imaging Profiles

A Surface-Modified Chylomicron Remnant-like Emulsion for Percutaneous Computed Tomography Lymphography: Synthesis and Preliminary Imaging Findings

Hepatobiliary Imaging Using a Novel Hepatocyte-Selective CT Contrast Agent

Lipid-based blood-pool CT imaging of the liver

Polyiodinated Triglyceride Analogs as Potential Computed Tomography Imaging Agents for the Liver

Percutaneous CT Lymphography Using a New Polyiodinated Biomimetic Microemulsion

Imaging Efficacy of a Hepatocyte-Selective Polyiodinated Triglyceride (DHOG-LE) for Contrast–enhanced CT

Abstract 3495: The novel phospholipid ether analog CLR1404 decreases glioblastoma stem cell proliferation, suppresses GBM growth, and improves survival

Computed tomography scanning of morris hepatomas with liver-specific polyiodinated triglycerides

Abberations in Phospholipase D Activity‐A Pharmacological Target for Cancer Detection

Biographical Sketch: Dr. Raymond E. Counsell

Methoxypoly(ethylene glycol)-conjugated carboxypeptidase A for solid tumor targeting

Combined hepatocyte-selective and blood-pool contrast agents for the CT detection of experimental liver tumors in rabbits

Biotinylated granulocyte/macrophage colony-stimulating factor analogs: effect of linkage chemistry on activity and binding

Potential tumor- or organ-imaging agents. 26. Polyiodinated 2-substituted triacylglycerols as hepatographic agents

Potential tumor- or organ-imaging agents. 27. Polyiodinated 1,3-disubstituted and 1,2,3-trisubstituted triacylglycerols

Physicochemical Characterization of a Synthetic Lipid Emulsion for Hepatocyte-Selective Delivery of Lipophilic Compounds: Application to Polyiodinated Triglycerides as Contrast Agents for Computed Tomography

Imaging efficacy of a hepatocyte-selective polyiodinated triglyceride for contrast-enhanced computed tomography

Computed tomography scanning of hepatic tumors with polyiodinated triglycerides

Lipoprotein Incorporation Enhances Radioiodinated Cholesteryl Ester Uptake into Steroid Hormone-Secreting Tissues

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