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Discovery of (3S,3aR)-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic Acid (PF-3882845), an Orally Efficacious Mineralocorticoid Receptor (MR) Antagonist for Hypertension and Nephropathy

Journal of medicinal chemistry, 2010-08, Vol.53 (16), p.5979-6002

2010

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Potent and Selective Nonpeptide Inhibitors of Caspases 3 and 7

Journal of medicinal chemistry, 2001-06, Vol.44 (12), p.2015-2026

2001

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Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 2. Discovery of 7-azaspiro[3.5]nonane urea PF-04862853, an orally efficacious inhibitor of fatty acid amide hydrolase (FAAH) for pain

Bioorganic & medicinal chemistry letters, 2011-11, Vol.21 (21), p.6545-6553

2011

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Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 1: Identification of 7-azaspiro[3.5]nonane and 1-oxa-8-azaspiro[4.5]decane as lead scaffolds

Bioorganic & medicinal chemistry letters, 2011-11, Vol.21 (21), p.6538-6544

2011

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Benzothiophene inhibitors of MK2. Part 2: Improvements in kinase selectivity and cell potency

Bioorganic & medicinal chemistry letters, 2009-08, Vol.19 (16), p.4882-4884

2009

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Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode

Bioorganic & medicinal chemistry letters, 2010-03, Vol.20 (5), p.1543-1547

2010

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Synthesis and Characterization of Novel Surfactants Based on 2-Hydroxy-4-(Methylthio)Butanoic Acid: 1. Anionic Surfactants

Journal of surfactants and detergents, 2015-09, Vol.18 (5), p.895-903

2015

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Chiral Organolithium Complexes: The Structure of β-Lithiated β-Phenylcarboxamides and the Mechanism of Asymmetric Substitution in the Presence of (−)-Sparteine

Journal of the American Chemical Society, 1996-11, Vol.118 (46), p.11391-11398

1996

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Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist

Journal of medicinal chemistry, 2018-12, Vol.61 (23), p.10415-10439

2018

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Discovery of (3 S ,3a R )-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2 H -benzo[ g ]indazole-7-carboxylic Acid (PF-3882845), an Orally Efficacious Mineralocorticoid Receptor (MR) Antagonist for Hypertension and Nephropathy

Journal of medicinal chemistry, 2010-08, Vol.53 (16), p.5979-6002

2010

Volltextzugriff (PDF)

Discovery of 3‑Cyano‑N‑(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)‑1H‑pyrrolo[2,3‑b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist

Journal of medicinal chemistry, 2018-12, Vol.61 (23), p.10415-10439

2018

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Potent and Selective Nonpeptide Inhibitors of Caspases 3 and 7 Inhibit Apoptosis and Maintain Cell Functionality

The Journal of biological chemistry, 2000-05, Vol.275 (21), p.16007-16014

2000

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Armed Conflict: A Model for Understanding and Intervention

Death studies, 2013-01, Vol.37 (1), p.61-88

Armed Conflict Work Group of the International Work Group on Death, Dying, and Bereavement

2013

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Preparation of 3-125I-benzyl-(6R,7S)-7-methoxy-3-acetoxymethyl-3- cephem-4-carboxamide-1,1-dioxide

Journal of labelled compounds & radiopharmaceuticals, 1999-01, Vol.42 (1), p.77-81

1999

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From Scarcity to Visibility: Gender Differences in the Careers of Doctoral Scientists and Engineers

Long, J. Scott, Ed

2001

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Efficacy and Safety of Evolocumab in Reducing Lipids and Cardiovascular Events

The New England journal of medicine, 2015-04, Vol.372 (16), p.1500-1509

2015

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Metal–organic frameworks: Structures and functional applications

Materials today (Kidlington, England), 2019-07, Vol.27, p.43-68

2019

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A GENERAL FRAMEWORK FOR COMPARING PREDICTIONS AND MARGINAL EFFECTS ACROSS MODELS

Sociological methodology, 2019-08, Vol.49 (1), p.152-189

2019

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Polymer structure-property requirements for stereolithographic 3D printing of soft tissue engineering scaffolds

Biomaterials, 2017-09, Vol.140, p.170-188

2017

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Using Predictions and Marginal Effects to Compare Groups in Regression Models for Binary Outcomes

Sociological methods & research, 2021-08, Vol.50 (3), p.1284-1320

2021

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De novo assembly of soybean wild relatives for pan-genome analysis of diversity and agronomic traits

Nature biotechnology, 2014-10, Vol.32 (10), p.1045-1052

2014

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Overcoming primary and acquired resistance to anti-PD-L1 therapy by induction and activation of tumor-residing cDC1s

Nature communications, 2020-10, Vol.11 (1), p.5415-5415, Article 5415

2020

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Temporary formation of highly conducting domain walls for non-destructive read-out of ferroelectric domain-wall resistance switching memories

Nature materials, 2018-01, Vol.17 (1), p.49-56

2018

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Five-Year Survival Outcomes From the PACIFIC Trial: Durvalumab After Chemoradiotherapy in Stage III Non-Small-Cell Lung Cancer

Journal of clinical oncology, 2022-04, Vol.40 (12), p.1301-1311

2022

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Discovery of (3S,3aR)-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic Acid (PF-3882845), an Orally Efficacious Mineralocorticoid Receptor (MR) Antagonist for Hypertension and Nephropathy

Potent and Selective Nonpeptide Inhibitors of Caspases 3 and 7

Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 2. Discovery of 7-azaspiro[3.5]nonane urea PF-04862853, an orally efficacious inhibitor of fatty acid amide hydrolase (FAAH) for pain

Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 1: Identification of 7-azaspiro[3.5]nonane and 1-oxa-8-azaspiro[4.5]decane as lead scaffolds

Benzothiophene inhibitors of MK2. Part 2: Improvements in kinase selectivity and cell potency

Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode

Synthesis and Characterization of Novel Surfactants Based on 2-Hydroxy-4-(Methylthio)Butanoic Acid: 1. Anionic Surfactants

Chiral Organolithium Complexes: The Structure of β-Lithiated β-Phenylcarboxamides and the Mechanism of Asymmetric Substitution in the Presence of (−)-Sparteine

Discovery of 3-Cyano- N-(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 H-pyrrolo[2,3- b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist

Discovery of (3 S ,3a R )-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2 H -benzo[ g ]indazole-7-carboxylic Acid (PF-3882845), an Orally Efficacious Mineralocorticoid Receptor (MR) Antagonist for Hypertension and Nephropathy

Discovery of 3‑Cyano‑N‑(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)‑1H‑pyrrolo[2,3‑b]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist

Potent and Selective Nonpeptide Inhibitors of Caspases 3 and 7 Inhibit Apoptosis and Maintain Cell Functionality

Armed Conflict: A Model for Understanding and Intervention

Preparation of 3-125I-benzyl-(6R,7S)-7-methoxy-3-acetoxymethyl-3- cephem-4-carboxamide-1,1-dioxide

From Scarcity to Visibility: Gender Differences in the Careers of Doctoral Scientists and Engineers

Efficacy and Safety of Evolocumab in Reducing Lipids and Cardiovascular Events

Epacadostat plus pembrolizumab versus placebo plus pembrolizumab in patients with unresectable or metastatic melanoma (ECHO-301/KEYNOTE-252): a phase 3, randomised, double-blind study

Metal–organic frameworks: Structures and functional applications

A GENERAL FRAMEWORK FOR COMPARING PREDICTIONS AND MARGINAL EFFECTS ACROSS MODELS

Polymer structure-property requirements for stereolithographic 3D printing of soft tissue engineering scaffolds

Using Predictions and Marginal Effects to Compare Groups in Regression Models for Binary Outcomes

De novo assembly of soybean wild relatives for pan-genome analysis of diversity and agronomic traits

Overcoming primary and acquired resistance to anti-PD-L1 therapy by induction and activation of tumor-residing cDC1s

Temporary formation of highly conducting domain walls for non-destructive read-out of ferroelectric domain-wall resistance switching memories

Five-Year Survival Outcomes From the PACIFIC Trial: Durvalumab After Chemoradiotherapy in Stage III Non-Small-Cell Lung Cancer

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