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Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function

Molecular cell, 2017-05, Vol.66 (4), p.517-532.e9

2017

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Loss of autophagy causes a synthetic lethal deficiency in DNA repair

Proceedings of the National Academy of Sciences - PNAS, 2015-01, Vol.112 (3), p.773-778

2015

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Sphingosine 1-phosphate signalling in cancer

Biochemical Society transactions, 2012-02, Vol.40 (1), p.94-100

2012

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The Sphingosine Kinase 1 Inhibitor 2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole Induces Proteasomal Degradation of Sphingosine Kinase 1 in Mammalian Cells

The Journal of biological chemistry, 2010-12, Vol.285 (50), p.38841-38852

2010

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LRRK2 phosphorylation status and kinase activity regulate (macro)autophagy in a Rab8a/Rab10-dependent manner

Cell death & disease, 2023-07, Vol.14 (7), p.436-436, Article 436

2023

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Extracellular Adenosine Sensing—A Metabolic Cell Death Priming Mechanism Downstream of p53

Molecular cell, 2013-05, Vol.50 (3), p.394-406

2013

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Sphingosine Kinase 1 Induces Tolerance to Human Epidermal Growth Factor Receptor 2 and Prevents Formation of a Migratory Phenotype in Response to Sphingosine 1-Phosphate in Estrogen Receptor-Positive Breast Cancer Cells

Molecular and Cellular Biology, 2010-08, Vol.30 (15), p.3827-3841

2010

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Sphingosine 1-Phosphate Receptor 4 Uses HER2 (ERBB2) to Regulate Extracellular Signal Regulated Kinase-1/2 in MDA-MB-453 Breast Cancer Cells

The Journal of biological chemistry, 2010-11, Vol.285 (46), p.35957-35966

2010

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Lipid phosphate phosphatases form homo- and hetero-oligomers: catalytic competency, subcellular distribution and function

Biochemical journal, 2008-04, Vol.411 (2), p.371-377

2008

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p53 and senescence: A little goes a long way

Cell cycle (Georgetown, Tex.), 2010-10, Vol.9 (20), p.4052-4051

2010

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DRAM‐4 and DRAM‐5 are compensatory regulators of autophagy and cell survival in nutrient‐deprived conditions

The FEBS journal, 2022-07, Vol.289 (13), p.3752-3769

2022

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mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux

Molecular cell, 2019-10, Vol.76 (1), p.163-176.e8

2019

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ATG7 is a haploinsufficient repressor of tumor progression and promoter of metastasis

Proceedings of the National Academy of Sciences - PNAS, 2022-07, Vol.119 (28), p.e2113465119

2022

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Glycan degradation promotes macroautophagy

Proceedings of the National Academy of Sciences - PNAS, 2022-06, Vol.119 (26), p.e2111506119-e2111506119

2022

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Lipid phosphate phosphatase-1 regulates lysophosphatidic acid- and platelet-derived-growth-factor-induced cell migration

Biochemical journal, 2006-03, Vol.394 (Pt 2), p.495-500

2006

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Molecular Pathways Controlling Autophagy in Pancreatic Cancer

Frontiers in oncology, 2017-03, Vol.7, p.28-28

2017

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Identification and Validation of Novel Autophagy Regulators Using an Endogenous Readout siGENOME Screen

Methods in molecular biology (Clifton, N.J.), 2019, Vol.1880, p.359

2019

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Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver

Science advances, 2021-06, Vol.7 (23)

2021

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Emerging roles of transcriptional programs in autophagy regulation

Transcription, 2018-03, Vol.9 (2), p.131-136

2018

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Sphingosine 1-phosphate regulation of extracellular signal-regulated kinase-1/2 in embryonic stem cells

Stem cells and development, 2009-11, Vol.18 (9), p.1319-1330

2009

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The sphingosine 1-phosphate receptor 5 and sphingosine kinases 1 and 2 are localised in centrosomes: Possible role in regulating cell division

Cellular signalling, 2009-05, Vol.21 (5), p.675-684

2009

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The effect of hypoxia on lipid phosphate receptor and sphingosine kinase expression and mitogen-activated protein kinase signaling in human pulmonary smooth muscle cells

Prostaglandins & other lipid mediators, 2006-05, Vol.79 (3), p.278-286

2006

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High Expression of Sphingosine 1-Phosphate Receptors, S1P1 and S1P3 , Sphingosine Kinase 1, and Extracellular Signal-Regulated Kinase-1/2 Is Associated with Development of Tamoxifen Resistance in Estrogen Receptor-Positive Breast Cancer Patients

The American journal of pathology, 2010-11, Vol.177 (5), p.2205-2215

2010

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O-56 High expression of sphingosine 1-phosphate receptors, S1P1 and S1P3 , sphingosine kinase 1 and ERK-1/2 is associated with development of tamoxifen resistance in ER positive breast cancer patients

European journal of cancer supplements, 2010-09, Vol.8 (6), p.21-21

2010

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Lipid phosphate phosphatases form homo- and hetero-oligomers: catalytic competency, sub-cellular distribution and function

Biochemical journal, 2008-03, Vol.411 (2), p.371-377

2008

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Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function

Loss of autophagy causes a synthetic lethal deficiency in DNA repair

Sphingosine 1-phosphate signalling in cancer

The Sphingosine Kinase 1 Inhibitor 2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole Induces Proteasomal Degradation of Sphingosine Kinase 1 in Mammalian Cells

LRRK2 phosphorylation status and kinase activity regulate (macro)autophagy in a Rab8a/Rab10-dependent manner

Extracellular Adenosine Sensing—A Metabolic Cell Death Priming Mechanism Downstream of p53

Sphingosine Kinase 1 Induces Tolerance to Human Epidermal Growth Factor Receptor 2 and Prevents Formation of a Migratory Phenotype in Response to Sphingosine 1-Phosphate in Estrogen Receptor-Positive Breast Cancer Cells

Sphingosine 1-Phosphate Receptor 4 Uses HER2 (ERBB2) to Regulate Extracellular Signal Regulated Kinase-1/2 in MDA-MB-453 Breast Cancer Cells

Lipid phosphate phosphatases form homo- and hetero-oligomers: catalytic competency, subcellular distribution and function

p53 and senescence: A little goes a long way

DRAM‐4 and DRAM‐5 are compensatory regulators of autophagy and cell survival in nutrient‐deprived conditions

mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux

ATG7 is a haploinsufficient repressor of tumor progression and promoter of metastasis

Glycan degradation promotes macroautophagy

Lipid phosphate phosphatase-1 regulates lysophosphatidic acid- and platelet-derived-growth-factor-induced cell migration

Molecular Pathways Controlling Autophagy in Pancreatic Cancer

Identification and Validation of Novel Autophagy Regulators Using an Endogenous Readout siGENOME Screen

Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver

Emerging roles of transcriptional programs in autophagy regulation

Sphingosine 1-phosphate regulation of extracellular signal-regulated kinase-1/2 in embryonic stem cells

The sphingosine 1-phosphate receptor 5 and sphingosine kinases 1 and 2 are localised in centrosomes: Possible role in regulating cell division

The effect of hypoxia on lipid phosphate receptor and sphingosine kinase expression and mitogen-activated protein kinase signaling in human pulmonary smooth muscle cells

High Expression of Sphingosine 1-Phosphate Receptors, S1P1 and S1P3 , Sphingosine Kinase 1, and Extracellular Signal-Regulated Kinase-1/2 Is Associated with Development of Tamoxifen Resistance in Estrogen Receptor-Positive Breast Cancer Patients

O-56 High expression of sphingosine 1-phosphate receptors, S1P1 and S1P3 , sphingosine kinase 1 and ERK-1/2 is associated with development of tamoxifen resistance in ER positive breast cancer patients

Lipid phosphate phosphatases form homo- and hetero-oligomers: catalytic competency, sub-cellular distribution and function

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