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Malaria vaccines and human immune responses

Current opinion in microbiology, 2016-08, Vol.32, p.96-102

2016

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Qualification of standard membrane-feeding assay with Plasmodium falciparum malaria and potential improvements for future assays

PloS one, 2013-03, Vol.8 (3), p.e57909-e57909

2013

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Maintaining immunogenicity of blood stage and sexual stage subunit malaria vaccines when formulated in combination

PloS one, 2020-04, Vol.15 (4), p.e0232355-e0232355

2020

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Malaria Vaccines: Recent Advances and New Horizons

Cell host & microbe, 2018-07, Vol.24 (1), p.43-56

2018

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Enhancing blockade of Plasmodium falciparum erythrocyte invasion: assessing combinations of antibodies against PfRH5 and other merozoite antigens

PLoS pathogens, 2012-11, Vol.8 (11), p.e1002991-e1002991

2012

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Immune Responses in Malaria

Cold Spring Harbor perspectives in medicine, 2017-08, Vol.7 (8), p.a025577

2017

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Safety and immunogenicity of a plant-produced Pfs25 virus-like particle as a transmission blocking vaccine against malaria: A Phase 1 dose-escalation study in healthy adults

Vaccine, 2018-09, Vol.36 (39), p.5865-5871

2018

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Overcoming antigenic diversity by enhancing the immunogenicity of conserved epitopes on the malaria vaccine candidate apical membrane antigen-1

PLoS pathogens, 2013-12, Vol.9 (12), p.e1003840-e1003840

2013

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Enhancing immunogenicity and transmission-blocking activity of malaria vaccines by fusing Pfs25 to IMX313 multimerization technology

Scientific reports, 2016-01, Vol.6 (1), p.18848-18848, Article 18848

2016

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Malaria vaccine candidates displayed on novel virus-like particles are immunogenic and induce transmission-blocking activity

PloS one, 2019-09, Vol.14 (9), p.e0221733-e0221733

2019

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A malaria vaccine adjuvant based on recombinant antigen binding to liposomes

Nature nanotechnology, 2018-12, Vol.13 (12), p.1174-1181

2018

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Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion

Nature communications, 2022-10, Vol.13 (1), p.5888-5888, Article 5888

2022

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Transmission-blocking activity is determined by transmission-reducing activity and number of control oocysts in Plasmodium falciparum standard membrane-feeding assay

Vaccine, 2016-07, Vol.34 (35), p.4145-4151

2016

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Structure guided mimicry of an essential P. falciparum receptor-ligand complex enhances cross neutralizing antibodies

Nature communications, 2023-09, Vol.14 (1), p.5879-5879, Article 5879

2023

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Nanoassembly routes stimulate conflicting antibody quantity and quality for transmission-blocking malaria vaccines

Scientific reports, 2017-06, Vol.7 (1), p.3811-14, Article 3811

2017

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RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology

Proceedings of the National Academy of Sciences - PNAS, 2020-08, Vol.117 (32), p.19465-19474

2020

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Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies

Nature communications, 2022-09, Vol.13 (1), p.5603-5603, Article 5603

2022

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A Universal Plug-and-Display Vaccine Carrier Based on HBsAg VLP to Maximize Effective Antibody Response

Frontiers in immunology, 2019-12, Vol.10, p.2931-2931

2019

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Immunization with a functional protein complex required for erythrocyte invasion protects against lethal malaria

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (28), p.10311-10316

2014

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Structure-based design of a strain transcending AMA1-RON2L malaria vaccine

Nature communications, 2023-09, Vol.14 (1), p.5345-5345, Article 5345

2023

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Increased CD40 Expression Enhances Early STING-Mediated Type I Interferon Response and Host Survival in a Rodent Malaria Model

PLoS pathogens, 2016-10, Vol.12 (10), p.e1005930-e1005930

2016

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Functional Comparison of Plasmodium falciparum Transmission-Blocking Vaccine Candidates by the Standard Membrane-Feeding Assay

Infection and Immunity, 2013-12, Vol.81 (12), p.4377-4382

2013

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Engineering the chloroplast targeted malarial vaccine antigens in Chlamydomonas starch granules

PloS one, 2010-12, Vol.5 (12), p.e15424-e15424

2010

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Malaria vaccines and human immune responses

Qualification of standard membrane-feeding assay with Plasmodium falciparum malaria and potential improvements for future assays

Maintaining immunogenicity of blood stage and sexual stage subunit malaria vaccines when formulated in combination

Phase Ia clinical evaluation of the safety and immunogenicity of the Plasmodium falciparum blood-stage antigen AMA1 in ChAd63 and MVA vaccine vectors

Malaria Vaccines: Recent Advances and New Horizons

Enhancing blockade of Plasmodium falciparum erythrocyte invasion: assessing combinations of antibodies against PfRH5 and other merozoite antigens

Immune Responses in Malaria

Safety and immunogenicity of a plant-produced Pfs25 virus-like particle as a transmission blocking vaccine against malaria: A Phase 1 dose-escalation study in healthy adults

Overcoming antigenic diversity by enhancing the immunogenicity of conserved epitopes on the malaria vaccine candidate apical membrane antigen-1

Enhancing immunogenicity and transmission-blocking activity of malaria vaccines by fusing Pfs25 to IMX313 multimerization technology

Malaria vaccine candidates displayed on novel virus-like particles are immunogenic and induce transmission-blocking activity

A malaria vaccine adjuvant based on recombinant antigen binding to liposomes

Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion

Transmission-blocking activity is determined by transmission-reducing activity and number of control oocysts in Plasmodium falciparum standard membrane-feeding assay

Structure guided mimicry of an essential P. falciparum receptor-ligand complex enhances cross neutralizing antibodies

Nanoassembly routes stimulate conflicting antibody quantity and quality for transmission-blocking malaria vaccines

RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology

Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies

A Universal Plug-and-Display Vaccine Carrier Based on HBsAg VLP to Maximize Effective Antibody Response

Immunization with a functional protein complex required for erythrocyte invasion protects against lethal malaria

Structure-based design of a strain transcending AMA1-RON2L malaria vaccine

Increased CD40 Expression Enhances Early STING-Mediated Type I Interferon Response and Host Survival in a Rodent Malaria Model

Functional Comparison of Plasmodium falciparum Transmission-Blocking Vaccine Candidates by the Standard Membrane-Feeding Assay

Impact on malaria parasite multiplication rates in infected volunteers of the protein-in-adjuvant vaccine AMA1-C1/Alhydrogel+CPG 7909

Engineering the chloroplast targeted malarial vaccine antigens in Chlamydomonas starch granules

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