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Nuclear Receptor Coactivators: Master Regulators of Human Health and Disease

Annual review of medicine, 2014-01, Vol.65 (1), p.279-292

2014

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Nuclear receptor coregulators: modulators of pathology and therapeutic targets

Nature reviews. Endocrinology, 2012-10, Vol.8 (10), p.598-604

2012

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Drug Combination in Cancer Treatment-From Cocktails to Conjugated Combinations

Cancers, 2021-02, Vol.13 (4), p.669

2021

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The Expanding Cosmos of Nuclear Receptor Coactivators

Cell, 2006-05, Vol.125 (3), p.411-414

2006

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XBP1 links the 12-hour clock to NAFLD and regulation of membrane fluidity and lipid homeostasis

Nature communications, 2020-12, Vol.11 (1), p.6215-6215, Article 6215

2020

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USP15-dependent lysosomal pathway controls p53-R175H turnover in ovarian cancer cells

Nature communications, 2018-03, Vol.9 (1), p.1270-13, Article 1270

2018

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Steroid receptor coactivator-3 inhibition generates breast cancer antitumor immune microenvironment

Breast cancer research : BCR, 2022-10, Vol.24 (1), p.73-73, Article 73

2022

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Steroid receptor coactivators - their role in immunity

Frontiers in immunology, 2022-12, Vol.13, p.1079011-1079011

2022

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Targeting NSD2-mediated SRC-3 liquid-liquid phase separation sensitizes bortezomib treatment in multiple myeloma

Nature communications, 2021-02, Vol.12 (1), p.1022-14, Article 1022

2021

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Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover

Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (17), p.6997-7002

2013

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Development of potent small-molecule inhibitors to drug the undruggable steroid receptor coactivator-3

Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (18), p.4970-4975

2016

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Inhibition of SRC-3 as a potential therapeutic strategy for aggressive mantle cell lymphoma

PloS one, 2024-04, Vol.19 (4), p.e0289902-e0289902

2024

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Steroid receptor coactivators in Treg and Th17 cell biology and function

Frontiers in immunology, 2024-04, Vol.15, p.1389041-1389041

2024

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Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death

Cancer cell, 2015-08, Vol.28 (2), p.240-252

2015

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SRC-3 Coactivator Governs Dynamic Estrogen-Induced Chromatin Looping Interactions during Transcription

Molecular cell, 2018-05, Vol.70 (4), p.679-694.e7

2018

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Defining the mammalian coactivation of hepatic 12-h clock and lipid metabolism

Cell reports (Cambridge), 2022-03, Vol.38 (10), p.110491-110491, Article 110491

2022

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ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion

The Journal of clinical investigation, 2012-05, Vol.122 (5), p.1869-1880

2012

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Steroid receptor coactivator 3 (SRC-3/AIB1) is enriched and functional in mouse and human Tregs

Scientific reports, 2021-02, Vol.11 (1), p.3441-3441, Article 3441

2021

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Proteomic Analysis of Coregulators Bound to ERα on DNA and Nucleosomes Reveals Coregulator Dynamics

Molecular cell, 2013-07, Vol.51 (2), p.185-199

2013

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SRC-3 Coactivator Functional Lifetime Is Regulated by a Phospho-Dependent Ubiquitin Time Clock

Cell, 2007-06, Vol.129 (6), p.1125-1140

2007

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SRC-3 inhibition blocks tumor growth of pancreatic ductal adenocarcinoma

Cancer letters, 2019-02, Vol.442, p.310-319

2019

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Steroid Receptor Coactivator-3 (SRC-3/AIB1) as a Novel Therapeutic Target in Triple Negative Breast Cancer and Its Inhibition with a Phospho-Bufalin Prodrug

PloS one, 2015-10, Vol.10 (10), p.e0140011-e0140011

2015

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Expanding functional diversity of the coactivators

Trends in biochemical sciences (Amsterdam. Regular ed.), 2005-03, Vol.30 (3), p.126-132

2005

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HER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes

Cancer research (Chicago, Ill.), 2016-03, Vol.76 (6), p.1463-1475

2016

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SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization

Genes & development, 2013-02, Vol.27 (3), p.274-287

2013

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Nuclear Receptor Coactivators: Master Regulators of Human Health and Disease

Nuclear receptor coregulators: modulators of pathology and therapeutic targets

Drug Combination in Cancer Treatment-From Cocktails to Conjugated Combinations

The Expanding Cosmos of Nuclear Receptor Coactivators

XBP1 links the 12-hour clock to NAFLD and regulation of membrane fluidity and lipid homeostasis

USP15-dependent lysosomal pathway controls p53-R175H turnover in ovarian cancer cells

Steroid receptor coactivator-3 inhibition generates breast cancer antitumor immune microenvironment

Steroid receptor coactivators - their role in immunity

Targeting NSD2-mediated SRC-3 liquid-liquid phase separation sensitizes bortezomib treatment in multiple myeloma

Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover

Development of potent small-molecule inhibitors to drug the undruggable steroid receptor coactivator-3

Inhibition of SRC-3 as a potential therapeutic strategy for aggressive mantle cell lymphoma

Steroid receptor coactivators in Treg and Th17 cell biology and function

Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death

SRC-3 Coactivator Governs Dynamic Estrogen-Induced Chromatin Looping Interactions during Transcription

Defining the mammalian coactivation of hepatic 12-h clock and lipid metabolism

ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion

Steroid receptor coactivator 3 (SRC-3/AIB1) is enriched and functional in mouse and human Tregs

Proteomic Analysis of Coregulators Bound to ERα on DNA and Nucleosomes Reveals Coregulator Dynamics

SRC-3 Coactivator Functional Lifetime Is Regulated by a Phospho-Dependent Ubiquitin Time Clock

SRC-3 inhibition blocks tumor growth of pancreatic ductal adenocarcinoma

Steroid Receptor Coactivator-3 (SRC-3/AIB1) as a Novel Therapeutic Target in Triple Negative Breast Cancer and Its Inhibition with a Phospho-Bufalin Prodrug

Expanding functional diversity of the coactivators

HER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes

SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization

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