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Non-Classical Inhibition of Carbonic Anhydrase

International Journal of Molecular Sciences, 2016-07, Vol.17 (7), p.1150-1150

2016

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Cancer Drug Development of Carbonic Anhydrase Inhibitors beyond the Active Site

Molecules (Basel, Switzerland), 2018-04, Vol.23 (5), p.1045

2018

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Asparagine synthetase: Function, structure, and role in disease

The Journal of biological chemistry, 2017-12, Vol.292 (49), p.19952-19958

2017

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4‑Hydroxy-3-nitro-5-ureido-benzenesulfonamides Selectively Target the Tumor-Associated Carbonic Anhydrase Isoforms IX and XII Showing Hypoxia-Enhanced Antiproliferative Profiles

Journal of medicinal chemistry, 2018-12, Vol.61 (23), p.10860-10874

2018

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Kinetic and X-ray crystallographic investigations on carbonic anhydrase isoforms I, II, IX and XII of a thioureido analog of SLC-0111

Bioorganic & medicinal chemistry, 2016-03, Vol.24 (5), p.976-981

2016

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The Structure of Carbonic Anhydrase IX Is Adapted for Low-pH Catalysis

Biochemistry (Easton), 2016-08, Vol.55 (33), p.4642-4653

2016

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Discovery of β‑Adrenergic Receptors Blocker–Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy

Journal of medicinal chemistry, 2018-06, Vol.61 (12), p.5380-5394

2018

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“Seriously Sweet”: Acesulfame K Exhibits Selective Inhibition Using Alternative Binding Modes in Carbonic Anhydrase Isoforms

Journal of medicinal chemistry, 2018-02, Vol.61 (3), p.1176-1181

2018

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Carbonic anhydrase II does not exhibit Nitrite reductase or Nitrous Anhydrase Activity

Free radical biology & medicine, 2018-03, Vol.117, p.1-5

2018

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Carbonic anhydrase II in complex with carboxylic acid‐based inhibitors

Acta crystallographica. Section F, Structural biology communications, 2019-03, Vol.75 (3), p.166-170

2019

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The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.930-939

2022

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Crystallography and Its Impact on Carbonic Anhydrase Research

International Journal of Medicinal Chemistry (Online), 2018-01, Vol.2018, p.1-21

2018

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Next Generation Sequencing of the Pig αβ TCR Repertoire Identifies the Porcine Invariant NKT Cell Receptor

The Journal of immunology (1950), 2019-04, Vol.202 (7), p.1981-1991

2019

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Discovery of New Sulfonamide Carbonic Anhydrase IX Inhibitors Incorporating Nitrogenous Bases

ACS medicinal chemistry letters, 2017-12, Vol.8 (12), p.1314-1319

2017

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The splicing component ISY1 regulates APE1 in base excision repair

DNA repair, 2020-02, Vol.86, p.102769-102769, Article 102769

2020

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Crystal Structure of Cleaved Serp-1, a Myxomavirus-Derived Immune Modulating Serpin: Structural Design of Serpin Reactive Center Loop Peptides with Improved Therapeutic Function

Biochemistry (Easton), 2018-02, Vol.57 (7), p.1096-1107

2018

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Characterization of a novel variant in siblings with Asparagine Synthetase Deficiency

Molecular genetics and metabolism, 2018-03, Vol.123 (3), p.317-325

2018

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Sweet Binders: Carbonic Anhydrase IX in Complex with Sucralose

ACS medicinal chemistry letters, 2018-07, Vol.9 (7), p.657-661

2018

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Mapping Selective Inhibition of the Cancer-Related Carbonic Anhydrase IX Using Structure–Activity Relationships of Glucosyl-Based Sulfamates

Journal of medicinal chemistry, 2015-08, Vol.58 (16), p.6630-6638

2015

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Active-site solvent replenishment observed during human carbonic anhydrase II catalysis

IUCrJ, 2018-01, Vol.5 (Pt 1), p.93-102

2018

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Carbonic anhydrase inhibitors: a review on the progress of patent literature (2011-2016)

Expert opinion on therapeutic patents, 2016-08, Vol.26 (8), p.947-956

2016

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Carbonic anhydrase II microcrystals suitable for XFEL studies

Acta crystallographica. Section F, Structural biology communications, 2018-06, Vol.74 (6), p.327-330

2018

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Observed surface lysine acetylation of human carbonic anhydrase II expressed in Escherichia coli

Protein science, 2015-11, Vol.24 (11), p.1800-1807

2015

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Microbatch Mixing: “Shaken not Stirred”, a Method for Macromolecular Microcrystal Production for Serial Crystallography

Crystal growth & design, 2016-11, Vol.16 (11), p.6214-6221

2016

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Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action

Journal of medicinal chemistry, 2020-07, Vol.63 (13), p.7422-7444

2020

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Non-Classical Inhibition of Carbonic Anhydrase

Cancer Drug Development of Carbonic Anhydrase Inhibitors beyond the Active Site

Asparagine synthetase: Function, structure, and role in disease

4‑Hydroxy-3-nitro-5-ureido-benzenesulfonamides Selectively Target the Tumor-Associated Carbonic Anhydrase Isoforms IX and XII Showing Hypoxia-Enhanced Antiproliferative Profiles

Kinetic and X-ray crystallographic investigations on carbonic anhydrase isoforms I, II, IX and XII of a thioureido analog of SLC-0111

The Structure of Carbonic Anhydrase IX Is Adapted for Low-pH Catalysis

Discovery of β‑Adrenergic Receptors Blocker–Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy

“Seriously Sweet”: Acesulfame K Exhibits Selective Inhibition Using Alternative Binding Modes in Carbonic Anhydrase Isoforms

Carbonic anhydrase II does not exhibit Nitrite reductase or Nitrous Anhydrase Activity

Carbonic anhydrase II in complex with carboxylic acid‐based inhibitors

The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII

Crystallography and Its Impact on Carbonic Anhydrase Research

Next Generation Sequencing of the Pig αβ TCR Repertoire Identifies the Porcine Invariant NKT Cell Receptor

Discovery of New Sulfonamide Carbonic Anhydrase IX Inhibitors Incorporating Nitrogenous Bases

The splicing component ISY1 regulates APE1 in base excision repair

Crystal Structure of Cleaved Serp-1, a Myxomavirus-Derived Immune Modulating Serpin: Structural Design of Serpin Reactive Center Loop Peptides with Improved Therapeutic Function

Characterization of a novel variant in siblings with Asparagine Synthetase Deficiency

Sweet Binders: Carbonic Anhydrase IX in Complex with Sucralose

Mapping Selective Inhibition of the Cancer-Related Carbonic Anhydrase IX Using Structure–Activity Relationships of Glucosyl-Based Sulfamates

Active-site solvent replenishment observed during human carbonic anhydrase II catalysis

Carbonic anhydrase inhibitors: a review on the progress of patent literature (2011-2016)

Carbonic anhydrase II microcrystals suitable for XFEL studies

Observed surface lysine acetylation of human carbonic anhydrase II expressed in Escherichia coli

Microbatch Mixing: “Shaken not Stirred”, a Method for Macromolecular Microcrystal Production for Serial Crystallography

Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action

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