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DNA replication stress: Causes, resolution and disease

Experimental cell research, 2014-11, Vol.329 (1), p.85-93

2014

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Validating the concept of mutational signatures with isogenic cell models

Nature communications, 2018-05, Vol.9 (1), p.1744-16, Article 1744

2018

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Interplay between Cellular Metabolism and the DNA Damage Response in Cancer

Cancers, 2020-07, Vol.12 (8), p.2051

2020

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Leveraging homologous recombination repair deficiency in sarcoma

EMBO molecular medicine, 2023-04, Vol.15 (4), p.e17453-n/a

2023

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Exploring the genetic space of the DNA damage response for cancer therapy through CRISPR‐based screens

Molecular oncology, 2022-11, Vol.16 (21), p.3778-3791

2022

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Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

Nature (London), 2014-04, Vol.508 (7495), p.222-227

2014

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Tissue Specific DNA Repair Outcomes Shape the Landscape of Genome Editing

Frontiers in genetics, 2021-09, Vol.12, p.728520-728520

2021

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Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks

Nature cell biology, 2006-01, Vol.8 (1), p.91-99

2006

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FANCD2-Associated Nuclease 1 Partially Compensates for the Lack of Exonuclease 1 in Mismatch Repair

Molecular and cellular biology, 2021-09, Vol.41 (9), p.e0030321

2021

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Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis

Nature communications, 2019-07, Vol.10 (1), p.3106-15, Article 3106

2019

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A metabolic map of the DNA damage response identifies PRDX1 in the control of nuclear ROS scavenging and aspartate availability

Molecular systems biology, 2023-07, Vol.19 (7), p.e11267-n/a

2023

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Programmed DNA breaks in lymphoid cells: repair mechanisms and consequences in human disease

Immunology, 2016-01, Vol.147 (1), p.11-20

2016

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Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48

Nature communications, 2018-06, Vol.9 (1), p.2280-14, Article 2280

2018

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Repair of UV-Induced DNA Damage Independent of Nucleotide Excision Repair Is Masked by MUTYH

Molecular cell, 2017-11, Vol.68 (4), p.797-807.e7

2017

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Mutational landscape of intestinal crypt cells after long-term in vivo exposure to high fat diet

Scientific reports, 2023-08, Vol.13 (1), p.13964-13964, Article 13964

2023

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A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN

Cell reports (Cambridge), 2016-04, Vol.15 (4), p.893-908

2016

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Targeting the DNA Repair Enzyme Polymerase θ in Cancer Therapy

Trends in Cancer, 2021-02, Vol.7 (2), p.98-111

2021

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Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia

Nature communications, 2017-11, Vol.8 (1), p.1238-8, Article 1238

2017

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MEK inhibitors block growth of lung tumours with mutations in ataxia–telangiectasia mutated

Nature communications, 2016-12, Vol.7 (1), p.13701-13, Article 13701

2016

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Pan-cancer analysis of the interplay between mutational signatures and cellular signaling

iScience, 2024-06, Vol.27 (6), p.109873-109873, Article 109873

2024

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Competition between NBS1 and ATMIN Controls ATM Signaling Pathway Choice

Cell reports (Cambridge), 2012-12, Vol.2 (6), p.1498-1504

2012

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Clickable Cisplatin Derivatives as Versatile Tools to Probe the DNA Damage Response to Chemotherapy

Frontiers in oncology, 2022-06, Vol.12, p.874201-874201

2022

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ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress

DNA repair, 2014-12, Vol.24, p.122-130

2014

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The Protein Kinase CK2 Facilitates Repair of Chromosomal DNA Single-Strand Breaks

Cell, 2004-04, Vol.117 (1), p.17-28

2004

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DNA replication stress: Causes, resolution and disease

Validating the concept of mutational signatures with isogenic cell models

Interplay between Cellular Metabolism and the DNA Damage Response in Cancer

Leveraging homologous recombination repair deficiency in sarcoma

Exploring the genetic space of the DNA damage response for cancer therapy through CRISPR‐based screens

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

Tissue Specific DNA Repair Outcomes Shape the Landscape of Genome Editing

Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks

FANCD2-Associated Nuclease 1 Partially Compensates for the Lack of Exonuclease 1 in Mismatch Repair

Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis

A metabolic map of the DNA damage response identifies PRDX1 in the control of nuclear ROS scavenging and aspartate availability

Programmed DNA breaks in lymphoid cells: repair mechanisms and consequences in human disease

Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48

Repair of UV-Induced DNA Damage Independent of Nucleotide Excision Repair Is Masked by MUTYH

High activation of STAT5A drives peripheral T-cell lymphoma and leukemia

Mutational landscape of intestinal crypt cells after long-term in vivo exposure to high fat diet

A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN

Targeting the DNA Repair Enzyme Polymerase θ in Cancer Therapy

Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia

MEK inhibitors block growth of lung tumours with mutations in ataxia–telangiectasia mutated

Pan-cancer analysis of the interplay between mutational signatures and cellular signaling

Competition between NBS1 and ATMIN Controls ATM Signaling Pathway Choice

Clickable Cisplatin Derivatives as Versatile Tools to Probe the DNA Damage Response to Chemotherapy

ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress

The Protein Kinase CK2 Facilitates Repair of Chromosomal DNA Single-Strand Breaks

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