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Scleraxis lineage cells contribute to organized bridging tissue during tendon healing and identify a subpopulation of resident tendon cells

The FASEB journal, 2019-07, Vol.33 (7), p.8578-8587

2019

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The cellular basis of fibrotic tendon healing: challenges and opportunities

Translational research : the journal of laboratory and clinical medicine, 2019-07, Vol.209, p.156-168

2019

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Depletion of Scleraxis-lineage cells during tendon healing transiently impairs multi-scale restoration of tendon structure during early healing

PloS one, 2022-10, Vol.17 (10), p.e0274227

2022

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Effects of Type II Diabetes Mellitus on Tendon Homeostasis and Healing

Journal of orthopaedic research, 2020-01, Vol.38 (1), p.13-22

2020

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Obesity/Type II diabetes alters macrophage polarization resulting in a fibrotic tendon healing response

PloS one, 2017-07, Vol.12 (7), p.e0181127-e0181127

2017

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Pharmacological antagonism of Ccr2+ cell recruitment to facilitate regenerative tendon healing

Journal of orthopaedic research, 2024-10

2024

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Impact of aging on tendon homeostasis, tendinopathy development, and impaired healing

Connective tissue research, 2023-01, Vol.64 (1), p.1-13

2023

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Deletion of NFKB1 enhances canonical NF-κB signaling and increases macrophage and myofibroblast content during tendon healing

Scientific reports, 2019-07, Vol.9 (1), p.10926-11, Article 10926

2019

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The Micromechanical Environment of the Impinged Achilles Tendon

Small (Weinheim an der Bergstrasse, Germany), 2024-11, Vol.20 (44), p.e2401015-n/a

2024

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CCR2 is expressed by tendon resident macrophage and T cells, while CCR2 deficiency impairs tendon healing via blunted involvement of tendon‐resident and circulating monocytes/macrophages

The FASEB journal, 2022-11, Vol.36 (11), p.e22607-n/a

2022

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Characterization of scar tissue biomechanics during adult murine flexor tendon healing

Journal of the mechanical behavior of biomedical materials, 2022-06, Vol.130, p.105192-105192, Article 105192

2022

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Development of a Murine Model of Pyogenic Flexor Tenosynovitis

Journal of bone and joint surgery. American volume, 2021-03, Vol.103 (5), p.432-438

2021

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Connexin 43 deficiency desensitizes bone to the effects of mechanical unloading through modulation of both arms of bone remodeling

Bone (New York, N.Y.), 2013-11, Vol.57 (1), p.76-83

2013

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Gap junction and hemichannel functions in osteocytes

Bone (New York, N.Y.), 2013-06, Vol.54 (2), p.205-212

2013

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Single-cell transcriptomics of popliteal lymphatic vessels and peripheral veins reveals altered lymphatic muscle and immune cell populations in the TNF-Tg arthritis model

Arthritis research & therapy, 2022-03, Vol.24 (1), p.64-64, Article 64

2022

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Inhibition of GSK-3β rescues the impairments in bone formation and mechanical properties associated with fracture healing in osteoblast selective connexin 43 deficient mice

PloS one, 2013-11, Vol.8 (11), p.e81399-e81399

2013

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Aging does not alter tendon mechanical properties during homeostasis, but does impair flexor tendon healing

Journal of orthopaedic research, 2017-12, Vol.35 (12), p.2716-2724

2017

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Drug Delivery Approaches to Improve Tendon Healing

Tissue engineering. Part B, Reviews, 2023-08, Vol.29 (4), p.369-386

2023

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Scleraxis-lineage cell depletion improves tendon healing and disrupts adult tendon homeostasis

eLife, 2021-01, Vol.10

2021

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Systemic EP4 Inhibition Increases Adhesion Formation in a Murine Model of Flexor Tendon Repair

PloS one, 2015-08, Vol.10 (8), p.e0136351

2015

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Obesity/Type II Diabetes Promotes Function-limiting Changes in Murine Tendons that are not reversed by Restoring Normal Metabolic Function

Scientific reports, 2018-06, Vol.8 (1), p.9218-10, Article 9218

2018

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Cell non-autonomous functions of S100a4 drive fibrotic tendon healing

eLife, 2019-05, Vol.8

2019

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Identification of Periostin as a critical niche for myofibroblast dynamics and fibrosis during tendon healing

Matrix biology, 2024-01, Vol.125, p.59-72

2024

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NF-κB activation persists into the remodeling phase of tendon healing and promotes myofibroblast survival

Science signaling, 2020-11, Vol.13 (658)

2020

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Scleraxis-lineage cells are required for tendon homeostasis and their depletion induces an accelerated extracellular matrix aging phenotype

eLife, 2023-01, Vol.12

2023

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Scleraxis lineage cells contribute to organized bridging tissue during tendon healing and identify a subpopulation of resident tendon cells

The cellular basis of fibrotic tendon healing: challenges and opportunities

Depletion of Scleraxis-lineage cells during tendon healing transiently impairs multi-scale restoration of tendon structure during early healing

Effects of Type II Diabetes Mellitus on Tendon Homeostasis and Healing

Obesity/Type II diabetes alters macrophage polarization resulting in a fibrotic tendon healing response

Pharmacological antagonism of Ccr2+ cell recruitment to facilitate regenerative tendon healing

Impact of aging on tendon homeostasis, tendinopathy development, and impaired healing

Deletion of NFKB1 enhances canonical NF-κB signaling and increases macrophage and myofibroblast content during tendon healing

The Micromechanical Environment of the Impinged Achilles Tendon

CCR2 is expressed by tendon resident macrophage and T cells, while CCR2 deficiency impairs tendon healing via blunted involvement of tendon‐resident and circulating monocytes/macrophages

Characterization of scar tissue biomechanics during adult murine flexor tendon healing

Development of a Murine Model of Pyogenic Flexor Tenosynovitis

Connexin 43 deficiency desensitizes bone to the effects of mechanical unloading through modulation of both arms of bone remodeling

Gap junction and hemichannel functions in osteocytes

Single-cell transcriptomics of popliteal lymphatic vessels and peripheral veins reveals altered lymphatic muscle and immune cell populations in the TNF-Tg arthritis model

Inhibition of GSK-3β rescues the impairments in bone formation and mechanical properties associated with fracture healing in osteoblast selective connexin 43 deficient mice

Aging does not alter tendon mechanical properties during homeostasis, but does impair flexor tendon healing

Drug Delivery Approaches to Improve Tendon Healing

Scleraxis-lineage cell depletion improves tendon healing and disrupts adult tendon homeostasis

Systemic EP4 Inhibition Increases Adhesion Formation in a Murine Model of Flexor Tendon Repair

Obesity/Type II Diabetes Promotes Function-limiting Changes in Murine Tendons that are not reversed by Restoring Normal Metabolic Function

Cell non-autonomous functions of S100a4 drive fibrotic tendon healing

Identification of Periostin as a critical niche for myofibroblast dynamics and fibrosis during tendon healing

NF-κB activation persists into the remodeling phase of tendon healing and promotes myofibroblast survival

Scleraxis-lineage cells are required for tendon homeostasis and their depletion induces an accelerated extracellular matrix aging phenotype

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