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Anticolorectal cancer activity of the omega-3 polyunsaturated fatty acid eicosapentaenoic acid

Gut, 2014-11, Vol.63 (11), p.1760-1768

2014

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Progress towards a clinically-successful ATR inhibitor for cancer therapy

Current research in pharmacology and drug discovery, 2021-01, Vol.2, p.100017-100017, Article 100017

2021

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Development of Novel Tumor-Targeted Theranostic Nanoparticles Activated by Membrane-Type Matrix Metalloproteinases for Combined Cancer Magnetic Resonance Imaging and Therapy

Small (Weinheim an der Bergstrasse, Germany), 2014-02, Vol.10 (3), p.566-575

2014

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Polysialic acid sustains cancer cell survival and migratory capacity in a hypoxic environment

Scientific reports, 2016-09, Vol.6 (1), p.33026, Article 33026

2016

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FGFR1-induced epithelial to mesenchymal transition through MAPK/PLCγ/COX-2-mediated mechanisms

PloS one, 2012-06, Vol.7 (6), p.e38972

2012

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Eicosapentaenoic acid free fatty acid prevents and suppresses colonic neoplasia in colitis‐associated colorectal cancer acting on Notch signaling and gut microbiota

International journal of cancer, 2014-11, Vol.135 (9), p.2004-2013

2014

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Effect of Eicosapentaenoic Acid on E-type Prostaglandin Synthesis and EP4 Receptor Signaling Human Colorectal Cancer Cells

Neoplasia (New York, N.Y.), 2010-08, Vol.12 (8), p.618,IN1-627,IN2

2010

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Cytochrome P450 isoforms 1A1, 1B1 AND 2W1 as targets for therapeutic intervention in head and neck cancer

Scientific reports, 2021-09, Vol.11 (1), p.18930-18930, Article 18930

2021

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Hypoxia‐Responsive Prodrug of ATR Inhibitor, AZD6738, Selectively Eradicates Treatment‐Resistant Cancer Cells

Advanced science, 2024-09, Vol.11 (34), p.e2403831-n/a

2024

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Pharmacological inhibition of polysialyltransferase ST8SiaII modulates tumour cell migration

PloS one, 2013-08, Vol.8 (8), p.e73366

2013

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Maleimide-Thiol Linkages Alter the Biodistribution of SN38 Therapeutic Microbubbles Compared to Biotin-Avidin While Preserving Parity in Tumoral Drug Delivery

Pharmaceutics, 2024-03, Vol.16 (3), p.434

2024

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Proteases in cancer drug delivery

Advanced drug delivery reviews, 2016-02, Vol.97, p.144-155

2016

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Detergent addition to tryptic digests and ion mobility separation prior to MS/MS improves peptide yield and protein identification for in situ proteomic investigation of frozen and formalin‐fixed paraffin‐embedded adenocarcinoma tissue sections

Proteomics (Weinheim), 2009-05, Vol.9 (10), p.2750-2763

2009

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A randomised trial of the effect of omega-3 polyunsaturated fatty acid supplements on the human intestinal microbiota

Gut, 2018-11, Vol.67 (11), p.1974-1983

2018

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Cancer-specific glycosylation of CD13 impacts its detection and activity in preclinical cancer tissues

iScience, 2023-11, Vol.26 (11), p.108219-108219, Article 108219

2023

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Is tumour-expressed aminopeptidase N (APN/CD13) structurally and functionally unique?

Biochimica et biophysica acta. Reviews on cancer, 2021-12, Vol.1876 (2), p.188641-188641, Article 188641

2021

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A Single Short 'Tone Burst' Results in Optimal Drug Delivery to Tumours Using Ultrasound-Triggered Therapeutic Microbubbles

Pharmaceutics, 2022-03, Vol.14 (3), p.622

2022

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How can the potential of the duocarmycins be unlocked for cancer therapy?

Drug discovery today, 2021-02, Vol.26 (2), p.577-584

2021

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Hypoxia-Selective Targeting by the Bioreductive Prodrug AQ4N in Patients with Solid Tumors: Results of a Phase I Study

Clinical cancer research, 2008-02, Vol.14 (4), p.1096-1104

2008

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Precision pharmacology: Mass spectrometry imaging and pharmacokinetic drug resistance

Critical reviews in oncology/hematology, 2019-09, Vol.141, p.153-162

2019

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Eicosapentaenoic acid and aspirin, alone and in combination, for the prevention of colorectal adenomas (seAFOod Polyp Prevention trial): a multicentre, randomised, double-blind, placebo-controlled, 2 × 2 factorial trial

The Lancet (British edition), 2018-12, Vol.392 (10164), p.2583-2594

2018

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Development of a Novel Tumor-Targeted Vascular Disrupting Agent Activated by Membrane-Type Matrix Metalloproteinases

Cancer research (Chicago, Ill.), 2010-09, Vol.70 (17), p.6902-6912

2010

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Recent advances in the analysis of polysialic acid from complex biological systems

Carbohydrate polymers, 2019-11, Vol.224, p.115145-115145, Article 115145

2019

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Targeted delivery of a colchicine analogue provides synergy with ATR inhibition in cancer cells

Biochemical pharmacology, 2022-07, Vol.201, p.115095-115095, Article 115095

2022

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Anticolorectal cancer activity of the omega-3 polyunsaturated fatty acid eicosapentaenoic acid

Progress towards a clinically-successful ATR inhibitor for cancer therapy

Development of Novel Tumor-Targeted Theranostic Nanoparticles Activated by Membrane-Type Matrix Metalloproteinases for Combined Cancer Magnetic Resonance Imaging and Therapy

Polysialic acid sustains cancer cell survival and migratory capacity in a hypoxic environment

FGFR1-induced epithelial to mesenchymal transition through MAPK/PLCγ/COX-2-mediated mechanisms

Eicosapentaenoic acid free fatty acid prevents and suppresses colonic neoplasia in colitis‐associated colorectal cancer acting on Notch signaling and gut microbiota

Effect of Eicosapentaenoic Acid on E-type Prostaglandin Synthesis and EP4 Receptor Signaling Human Colorectal Cancer Cells

Cytochrome P450 isoforms 1A1, 1B1 AND 2W1 as targets for therapeutic intervention in head and neck cancer

Hypoxia‐Responsive Prodrug of ATR Inhibitor, AZD6738, Selectively Eradicates Treatment‐Resistant Cancer Cells

Pharmacological inhibition of polysialyltransferase ST8SiaII modulates tumour cell migration

Maleimide-Thiol Linkages Alter the Biodistribution of SN38 Therapeutic Microbubbles Compared to Biotin-Avidin While Preserving Parity in Tumoral Drug Delivery

Proteases in cancer drug delivery

Detergent addition to tryptic digests and ion mobility separation prior to MS/MS improves peptide yield and protein identification for in situ proteomic investigation of frozen and formalin‐fixed paraffin‐embedded adenocarcinoma tissue sections

Randomised, placebo-controlled, phase 3 trial of the effect of the omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) on colorectal cancer recurrence and survival after surgery for resectable liver metastases: EPA for Metastasis Trial 2 (EMT2) study protocol

A randomised trial of the effect of omega-3 polyunsaturated fatty acid supplements on the human intestinal microbiota

Cancer-specific glycosylation of CD13 impacts its detection and activity in preclinical cancer tissues

Is tumour-expressed aminopeptidase N (APN/CD13) structurally and functionally unique?

A Single Short 'Tone Burst' Results in Optimal Drug Delivery to Tumours Using Ultrasound-Triggered Therapeutic Microbubbles

How can the potential of the duocarmycins be unlocked for cancer therapy?

Hypoxia-Selective Targeting by the Bioreductive Prodrug AQ4N in Patients with Solid Tumors: Results of a Phase I Study

Precision pharmacology: Mass spectrometry imaging and pharmacokinetic drug resistance

Eicosapentaenoic acid and aspirin, alone and in combination, for the prevention of colorectal adenomas (seAFOod Polyp Prevention trial): a multicentre, randomised, double-blind, placebo-controlled, 2 × 2 factorial trial

Development of a Novel Tumor-Targeted Vascular Disrupting Agent Activated by Membrane-Type Matrix Metalloproteinases

Recent advances in the analysis of polysialic acid from complex biological systems

Targeted delivery of a colchicine analogue provides synergy with ATR inhibition in cancer cells

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