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Cellular Internalization of Exosomes Occurs Through Phagocytosis

Traffic (Copenhagen, Denmark), 2010-05, Vol.11 (5), p.675-687

2010

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Inhibition of ADAM-TS4 and ADAM-TS5 Prevents Aggrecan Degradation in Osteoarthritic Cartilage

The Journal of biological chemistry, 2002-06, Vol.277 (25), p.22201-22208

2002

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Extraction chromatography–electrodeposition (EC–ED) process to recover palladium from high-level liquid waste

Nuclear science and techniques, 2017-12, Vol.28 (12), p.209-219, Article 175

2017

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Sites of Aggrecan Cleavage by Recombinant Human Aggrecanase-1 (ADAMTS-4)

The Journal of biological chemistry, 2000-06, Vol.275 (24), p.18566-18573

2000

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Discovery of a small molecule antagonist of the parathyroid hormone receptor by using an N-terminal parathyroid hormone peptide probe

Proceedings of the National Academy of Sciences - PNAS, 2007-04, Vol.104 (16), p.6846-6851

2007

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Pharmacologic and Genetic Manipulation of MMP-2 and -9 Affects Retinal Neovascularization in Rodent Models of OIR

Investigative ophthalmology & visual science, 2007-02, Vol.48 (2), p.907-915

2007

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Crystal structure of N ′-(2,6-dimethylphenyl)benzenecarboximidamide tetrahydrofuran monosolvate

Acta crystallographica. Section E, Crystallographic communications, 2015-01, Vol.71 (1), p.o28-o29

2015

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Membrane Localization of β-Amyloid 1-42 in Lysosomes: A POSSIBLE MECHANISM FOR LYSOSOME LABILIZATION

The Journal of biological chemistry, 2010-06, Vol.285 (26), p.19986-19996

2010

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α2-Macroglobulin Is a Novel Substrate for ADAMTS-4 and ADAMTS-5 and Represents an Endogenous Inhibitor of These Enzymes

The Journal of biological chemistry, 2004-04, Vol.279 (17), p.17554-17561

2004

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An alkyl-ended ansa-bis(amidine) and solvent-influenced complexation modes of its group IV metal derivatives

Polyhedron, 2013-11, Vol.65, p.161-169

2013

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Discovery and synthesis of cyclohexenyl derivatives as modulators of CC chemokine receptor 2 activity

Bioorganic & medicinal chemistry letters, 2016-01, Vol.26 (2), p.662-666

2016

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Discovery and Lead Optimization of a Novel Series of CC Chemokine Receptor 1 (CCR1)-Selective Piperidine Antagonists via Parallel Synthesis

Journal of medicinal chemistry, 2012-11, Vol.55 (22), p.9643-9653

2012

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Potent, selective, orally bioavailable inhibitors of tumor necrosis factor-α converting enzyme (TACE): Discovery of indole, benzofuran, imidazopyridine and pyrazolopyridine P1′ substituents

Bioorganic & medicinal chemistry, 2008-03, Vol.18 (6), p.1958-1962

2008

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Cloning and Characterization of ADAMTS11 , an Aggrecanase from the ADAMTS Family

The Journal of biological chemistry, 1999-08, Vol.274 (33), p.23443-23450

1999

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The Thrombospondin Motif of Aggrecanase-1 (ADAMTS-4) Is Critical for Aggrecan Substrate Recognition and Cleavage

The Journal of biological chemistry, 2000-08, Vol.275 (33), p.25791-25797

2000

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Characterization of human aggrecanase 2 (ADAM-TS5): substrate specificity studies and comparison with aggrecanase 1 (ADAM-TS4)

Matrix biology, 2002-10, Vol.21 (6), p.499-511

2002

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Hydantoins, triazolones, and imidazolones as selective non-hydroxamate inhibitors of tumor necrosis factor-α converting enzyme (TACE)

Bioorganic & medicinal chemistry letters, 2007-05, Vol.17 (10), p.2769-2774

2007

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Sultam Hydroxamates as Novel Matrix Metalloproteinase Inhibitors

Journal of medicinal chemistry, 2004-06, Vol.47 (12), p.2981-2983

2004

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Potent, exceptionally selective, orally bioavailable inhibitors of TNF-alpha Converting Enzyme (TACE): novel 2-substituted-1H-benzo[d]imidazol-1-yl)methyl)benzamide P1' substituents

Bioorganic & medicinal chemistry, 2008-03, Vol.18 (5), p.1577-1582

2008

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Discovery of low nanomolar non-hydroxamate inhibitors of tumor necrosis factor-α converting enzyme (TACE)

Bioorganic & medicinal chemistry letters, 2007, Vol.17 (1), p.266-271

2007

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Inhibition of tumor necrosis factor-alpha-converting enzyme by a selective antagonist protects brain from focal ischemic injury in rats

Molecular pharmacology, 2004-04, Vol.65 (4), p.890-896

2004

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Intracomplex electron transfer between ruthenium-cytochrome c derivatives and cytochrome c oxidase

Biochemistry (Easton), 1993-08, Vol.32 (33), p.8492-8498

1993

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Alkyl-ended ansa-bis(amidinate) ligands from aliphatic primary amines and multinuclear lithium derivatives

Mendeleev communications, 2013-09, Vol.23 (5), p.265-267

2013

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Discovery of γ-Lactam Hydroxamic Acids as Selective Inhibitors of Tumor Necrosis Factor α Converting Enzyme: Design, Synthesis, and Structure−Activity Relationships

Journal of medicinal chemistry, 2002-11, Vol.45 (23), p.4954-4957

2002

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Pharmacokinetics and pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a potent and selective inhibitor of tumor necrosis factor alpha-converting enzyme in rodents, dogs, chimpanzees, and humans

Drug metabolism and disposition, 2007-10, Vol.35 (10), p.1916

2007

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Cellular Internalization of Exosomes Occurs Through Phagocytosis

Inhibition of ADAM-TS4 and ADAM-TS5 Prevents Aggrecan Degradation in Osteoarthritic Cartilage

Extraction chromatography–electrodeposition (EC–ED) process to recover palladium from high-level liquid waste

Sites of Aggrecan Cleavage by Recombinant Human Aggrecanase-1 (ADAMTS-4)

Discovery of a small molecule antagonist of the parathyroid hormone receptor by using an N-terminal parathyroid hormone peptide probe

Pharmacologic and Genetic Manipulation of MMP-2 and -9 Affects Retinal Neovascularization in Rodent Models of OIR

Crystal structure of N ′-(2,6-dimethylphenyl)benzenecarboximidamide tetrahydrofuran monosolvate

Membrane Localization of β-Amyloid 1-42 in Lysosomes: A POSSIBLE MECHANISM FOR LYSOSOME LABILIZATION

α2-Macroglobulin Is a Novel Substrate for ADAMTS-4 and ADAMTS-5 and Represents an Endogenous Inhibitor of These Enzymes

An alkyl-ended ansa-bis(amidine) and solvent-influenced complexation modes of its group IV metal derivatives

Discovery and synthesis of cyclohexenyl derivatives as modulators of CC chemokine receptor 2 activity

Discovery and Lead Optimization of a Novel Series of CC Chemokine Receptor 1 (CCR1)-Selective Piperidine Antagonists via Parallel Synthesis

Potent, selective, orally bioavailable inhibitors of tumor necrosis factor-α converting enzyme (TACE): Discovery of indole, benzofuran, imidazopyridine and pyrazolopyridine P1′ substituents

Cloning and Characterization of ADAMTS11 , an Aggrecanase from the ADAMTS Family

The Thrombospondin Motif of Aggrecanase-1 (ADAMTS-4) Is Critical for Aggrecan Substrate Recognition and Cleavage

Characterization of human aggrecanase 2 (ADAM-TS5): substrate specificity studies and comparison with aggrecanase 1 (ADAM-TS4)

Hydantoins, triazolones, and imidazolones as selective non-hydroxamate inhibitors of tumor necrosis factor-α converting enzyme (TACE)

Sultam Hydroxamates as Novel Matrix Metalloproteinase Inhibitors

Potent, exceptionally selective, orally bioavailable inhibitors of TNF-alpha Converting Enzyme (TACE): novel 2-substituted-1H-benzo[d]imidazol-1-yl)methyl)benzamide P1' substituents

Discovery of low nanomolar non-hydroxamate inhibitors of tumor necrosis factor-α converting enzyme (TACE)

Inhibition of tumor necrosis factor-alpha-converting enzyme by a selective antagonist protects brain from focal ischemic injury in rats

Intracomplex electron transfer between ruthenium-cytochrome c derivatives and cytochrome c oxidase

Alkyl-ended ansa-bis(amidinate) ligands from aliphatic primary amines and multinuclear lithium derivatives

Discovery of γ-Lactam Hydroxamic Acids as Selective Inhibitors of Tumor Necrosis Factor α Converting Enzyme: Design, Synthesis, and Structure−Activity Relationships

Pharmacokinetics and pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a potent and selective inhibitor of tumor necrosis factor alpha-converting enzyme in rodents, dogs, chimpanzees, and humans

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