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TSC2 regulates lysosome biogenesis via a non-canonical RAGC and TFEB-dependent mechanism

Nature communications, 2021-07, Vol.12 (1), p.4245-4245, Article 4245

2021

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Glycosyltransferases: mechanisms and applications in natural product development

Chemical Society reviews, 2015-11, Vol.44 (22), p.835-8374

2015

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mTORC1 upregulates B7-H3/CD276 to inhibit antitumor T cells and drive tumor immune evasion

Nature communications, 2023-03, Vol.14 (1), p.1214-1214, Article 1214

2023

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MITF is a driver oncogene and potential therapeutic target in kidney angiomyolipoma tumors through transcriptional regulation of CYR61

Oncogene, 2021-01, Vol.40 (1), p.112-126

2021

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Bi-steric mTORC1 inhibitors induce apoptotic cell death in tumor models with hyperactivated mTORC1

The Journal of clinical investigation, 2023-11, Vol.133 (21), p.1-16

2023

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Rapamycin-upregulated miR-29b promotes mTORC1-hyperactive cell growth in TSC2-deficient cells by downregulating tumor suppressor retinoic acid receptor β (RARβ)

Oncogene, 2019-12, Vol.38 (49), p.7367-7383

2019

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The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells

The Journal of biological chemistry, 2015-08, Vol.290 (34), p.20827-20840

2015

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p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis

Cancer research (Chicago, Ill.), 2017-06, Vol.77 (12), p.3255-3267

2017

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Combined alkali and acid pretreatment of spent mushroom substrate for reducing sugar and biofertilizer production

Bioresource technology, 2013-05, Vol.136, p.257-266

2013

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Immunotherapy for Lymphangioleiomyomatosis and Tuberous Sclerosis: Progress and Future Directions

Chest, 2019-12, Vol.156 (6), p.1062-1067

2019

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Vitamin D binding protein: a new biomarker of disease severity in lymphangioleiomyomatosis

The European respiratory journal, 2018-11, Vol.52 (5), p.1801886

2018

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Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells

Proceedings of the National Academy of Sciences - PNAS, 2021-09, Vol.118 (39), p.1

2021

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PtdIns(3,4,5)P₃-dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis

Proceedings of the National Academy of Sciences - PNAS, 2020-11, Vol.117 (45), p.28056-28067

2020

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Protease activity sensors enable real-time treatment response monitoring in lymphangioleiomyomatosis

The European respiratory journal, 2022-04, Vol.59 (4), p.2100664

2022

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TSC2 regulates microRNA biogenesis via mTORC1 and GSK3β

Human molecular genetics, 2018-05, Vol.27 (9), p.1654-1663

2018

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Verification of the ability of Cu to dissolve in BCC δ in a δ-γ Solid Solution above 1200 °C and boosting δ nano-hardness in Cu-containing PHSS

Scripta materialia, 2022-04, Vol.211, p.114505, Article 114505

2022

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PtdIns(3,4,5)P3-dependent Rac Exchanger 1 (PREX1) Rac-Guanine Nucleotide Exchange Factor (GEF) Activity Promotes Breast Cancer Cell Proliferation and Tumor Growth via Activation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Signaling

The Journal of biological chemistry, 2016-08, Vol.291 (33), p.17258-17270

2016

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TSC2-deficient tumors have evidence of T cell exhaustion and respond to anti-PD-1/anti-CTLA-4 immunotherapy

JCI insight, 2018-04, Vol.3 (8)

2018

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Rapamycin-induced miR-21 promotes mitochondrial homeostasis and adaptation in mTORC1 activated cells

Oncotarget, 2017-09, Vol.8 (39), p.64714-64727

2017

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INPP4A/INPP4B and P-Rex proteins: Related but different?

Advances in biological regulation, 2012-01, Vol.52 (1), p.265-279

2012

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Immunotherapy for Lymphangioleiomyomatosis and Tuberous Sclerosis

Chest, 2019-12, Vol.156 (6), p.1062-1067

2019

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Abstract 1026: Bi-steric mTORC1-selective inhibitors demonstrate improved potency and efficacy in tumors with mTORC1 hyperactivation

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1026-1026

2021

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Abstract A28: Rapamycin-upregulated miR-29b promotes mTORC1-hyperactivative cell growth by downregulating retinoic acid receptor β (RARβ)

Molecular cancer research, 2020-10, Vol.18 (10_Supplement), p.A28-A28

2020

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Abstract B13: Targeting mTOR/JUN/AXL pathway in TSC-related tumors

Molecular cancer research, 2020-10, Vol.18 (10_Supplement), p.B13-B13

2020

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Rapamycin-upregulated miR-29b promotes mTORC1-hyperactive cell growth in TSC2-deficient cells by downregulating tumor suppressor retinoic acid receptor [beta]

Oncogene, 2019-12, Vol.38 (49), p.7367

2019

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TSC2 regulates lysosome biogenesis via a non-canonical RAGC and TFEB-dependent mechanism

Glycosyltransferases: mechanisms and applications in natural product development

mTORC1 upregulates B7-H3/CD276 to inhibit antitumor T cells and drive tumor immune evasion

MITF is a driver oncogene and potential therapeutic target in kidney angiomyolipoma tumors through transcriptional regulation of CYR61

Bi-steric mTORC1 inhibitors induce apoptotic cell death in tumor models with hyperactivated mTORC1

Rapamycin-upregulated miR-29b promotes mTORC1-hyperactive cell growth in TSC2-deficient cells by downregulating tumor suppressor retinoic acid receptor β (RARβ)

The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells

p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis

Combined alkali and acid pretreatment of spent mushroom substrate for reducing sugar and biofertilizer production

Immunotherapy for Lymphangioleiomyomatosis and Tuberous Sclerosis: Progress and Future Directions

Vitamin D binding protein: a new biomarker of disease severity in lymphangioleiomyomatosis

Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells

PtdIns(3,4,5)P₃-dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis

Protease activity sensors enable real-time treatment response monitoring in lymphangioleiomyomatosis

TSC2 regulates microRNA biogenesis via mTORC1 and GSK3β

Verification of the ability of Cu to dissolve in BCC δ in a δ-γ Solid Solution above 1200 °C and boosting δ nano-hardness in Cu-containing PHSS

PtdIns(3,4,5)P3-dependent Rac Exchanger 1 (PREX1) Rac-Guanine Nucleotide Exchange Factor (GEF) Activity Promotes Breast Cancer Cell Proliferation and Tumor Growth via Activation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Signaling

TSC2-deficient tumors have evidence of T cell exhaustion and respond to anti-PD-1/anti-CTLA-4 immunotherapy

Rapamycin-induced miR-21 promotes mitochondrial homeostasis and adaptation in mTORC1 activated cells

INPP4A/INPP4B and P-Rex proteins: Related but different?

Immunotherapy for Lymphangioleiomyomatosis and Tuberous Sclerosis

Abstract 1026: Bi-steric mTORC1-selective inhibitors demonstrate improved potency and efficacy in tumors with mTORC1 hyperactivation

Abstract A28: Rapamycin-upregulated miR-29b promotes mTORC1-hyperactivative cell growth by downregulating retinoic acid receptor β (RARβ)

Abstract B13: Targeting mTOR/JUN/AXL pathway in TSC-related tumors

Rapamycin-upregulated miR-29b promotes mTORC1-hyperactive cell growth in TSC2-deficient cells by downregulating tumor suppressor retinoic acid receptor [beta]

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