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Shared mechanisms of neural circuit disruption in tuberous sclerosis across lifespan: Bridging neurodevelopmental and neurodegenerative pathology

Frontiers in genetics, 2022-11, Vol.13, p.997461-997461

Litwa, Karen

2022

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Cytoskeletal regulation of synaptogenesis in a model of human fetal brain development

Journal of neuroscience research, 2020-11, Vol.98 (11), p.2148-2165

2020

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Non-muscle myosin II in disease: mechanisms and therapeutic opportunities

Disease models & mechanisms, 2015-12, Vol.8 (12), p.1495-1515

2015

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ROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity

The Journal of cell biology, 2015-07, Vol.210 (2), p.225-242

2015

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Cannabidiol inhibits neuroinflammatory responses and circuit-associated synaptic loss following damage to a songbird vocal pre-motor cortical-like region

Scientific reports, 2023-05, Vol.13 (1), p.7907-7907, Article 7907

2023

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Effects of the Selective Serotonin Reuptake Inhibitor Fluoxetine on Developing Neural Circuits in a Model of the Human Fetal Cortex

International journal of molecular sciences, 2021-10, Vol.22 (19), p.10457

2021

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CB1 antagonism increases excitatory synaptogenesis in a cortical spheroid model of fetal brain development

Scientific reports, 2021-04, Vol.11 (1), p.1-17, Article 9356

2021

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Breaking down to build up: Neuroligin's C-terminal domain strengthens the synapse

The Journal of cell biology, 2016-02, Vol.212 (4), p.375-377

Newell-Litwa, Karen A

2016

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Stem cell models of human synapse development and degeneration

Molecular biology of the cell, 2018-11, Vol.29 (24), p.2913-2921

2018

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Derivation of Actin‐Binding Peptides from a Cofilin Scaffold: A Rational Approach

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Dynamic cytoplasmic projections connect mammalian spermatogonia in vivo

Development (Cambridge), 2018-08, Vol.145 (15)

2018

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Cell Migration: PKA and RhoA Set the Pace

Current biology, 2011-08, Vol.21 (15), p.R596-R598

2011

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Synaptic Hyaluronan Synthesis and CD44-Mediated Signaling Coordinate Neural Circuit Development

Cells (Basel, Switzerland), 2021-09, Vol.10 (10), p.2574

2021

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The effect of rho kinase inhibition on morphological and electrophysiological maturity in iPSC-derived neurons

Cell and tissue research, 2019-03, Vol.375 (3), p.641-654

2019

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The Applicability of Current Turbidimetric Approaches for Analyzing Fibrin Fibers and Other Filamentous Networks

Biomolecules (Basel, Switzerland), 2022-06, Vol.12 (6), p.807

2022

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Acyl-CoA synthetase 6 is required for brain docosahexaenoic acid retention and neuroprotection during aging

JCI insight, 2021-06, Vol.6 (11)

2021

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Myosin IIA/IIB restrict adhesive and protrusive signaling to generate front-back polarity in migrating cells

The Journal of cell biology, 2011-04, Vol.193 (2), p.381-396

2011

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RhoGTPase Regulators Orchestrate Distinct Stages of Synaptic Development

PloS one, 2017-01, Vol.12 (1), p.e0170464-e0170464

2017

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Roles of BLOC-1 and adaptor protein-3 complexes in cargo sorting to synaptic vesicles

Molecular biology of the cell, 2009-03, Vol.20 (5), p.1441-1453

2009

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Myosin IIb activity and phosphorylation status determines dendritic spine and post-synaptic density morphology

PloS one, 2011-08, Vol.6 (8), p.e24149-e24149

2011

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Neuronal and non-neuronal functions of the AP-3 sorting machinery

Journal of cell science, 2007-02, Vol.120 (4), p.531-541

2007

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Hyaluronan regulates synapse formation and function in developing neural networks

Scientific reports, 2020-10, Vol.10 (1), p.16459, Article 16459

2020

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Human-Derived Brain Models: Windows into Neuropsychiatric Disorders and Drug Therapies

Assay and drug development technologies, 2020-03, Vol.18 (2), p.79-88

2020

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Hermansky-Pudlak Protein Complexes, AP-3 and BLOC-1, Differentially Regulate Presynaptic Composition in the Striatum and Hippocampus

The Journal of neuroscience, 2010-01, Vol.30 (3), p.820-831

2010

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Distinct roles of galactose-1P in galactose-mediated growth arrest of yeast deficient in galactose-1P uridylyltransferase (GALT) and UDP-galactose 4′-epimerase (GALE)

Molecular genetics and metabolism, 2008-02, Vol.93 (2), p.160-171

2008

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Shared mechanisms of neural circuit disruption in tuberous sclerosis across lifespan: Bridging neurodevelopmental and neurodegenerative pathology

Cytoskeletal regulation of synaptogenesis in a model of human fetal brain development

Non-muscle myosin II in disease: mechanisms and therapeutic opportunities

ROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity

Cannabidiol inhibits neuroinflammatory responses and circuit-associated synaptic loss following damage to a songbird vocal pre-motor cortical-like region

Effects of the Selective Serotonin Reuptake Inhibitor Fluoxetine on Developing Neural Circuits in a Model of the Human Fetal Cortex

CB1 antagonism increases excitatory synaptogenesis in a cortical spheroid model of fetal brain development

Breaking down to build up: Neuroligin's C-terminal domain strengthens the synapse

Stem cell models of human synapse development and degeneration

Derivation of Actin‐Binding Peptides from a Cofilin Scaffold: A Rational Approach

Dynamic cytoplasmic projections connect mammalian spermatogonia in vivo

Cell Migration: PKA and RhoA Set the Pace

Synaptic Hyaluronan Synthesis and CD44-Mediated Signaling Coordinate Neural Circuit Development

The effect of rho kinase inhibition on morphological and electrophysiological maturity in iPSC-derived neurons

The Applicability of Current Turbidimetric Approaches for Analyzing Fibrin Fibers and Other Filamentous Networks

Acyl-CoA synthetase 6 is required for brain docosahexaenoic acid retention and neuroprotection during aging

Myosin IIA/IIB restrict adhesive and protrusive signaling to generate front-back polarity in migrating cells

RhoGTPase Regulators Orchestrate Distinct Stages of Synaptic Development

Roles of BLOC-1 and adaptor protein-3 complexes in cargo sorting to synaptic vesicles

Myosin IIb activity and phosphorylation status determines dendritic spine and post-synaptic density morphology

Neuronal and non-neuronal functions of the AP-3 sorting machinery

Hyaluronan regulates synapse formation and function in developing neural networks

Human-Derived Brain Models: Windows into Neuropsychiatric Disorders and Drug Therapies

Hermansky-Pudlak Protein Complexes, AP-3 and BLOC-1, Differentially Regulate Presynaptic Composition in the Striatum and Hippocampus

Distinct roles of galactose-1P in galactose-mediated growth arrest of yeast deficient in galactose-1P uridylyltransferase (GALT) and UDP-galactose 4′-epimerase (GALE)

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