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Activated protein C targets immune cells and rheumatoid synovial fibroblasts to prevent inflammatory arthritis in mice

Rheumatology (Oxford, England), 2019-10, Vol.58 (10), p.1850-1860

2019

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Effects of culture conditions and exposure to catabolic stimulators (IL-1 and retinoic acid) on the expression of matrix metalloproteinases (MMPs) and disintegrin metalloproteinases (ADAMs) by articular cartilage chondrocytes

Matrix biology, 1999-06, Vol.18 (3), p.225-237

1999

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Mechanisms involved in cartilage proteoglycan catabolism

Matrix biology, 2000-08, Vol.19 (4), p.333-344

2000

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n-3 Fatty Acids Specifically Modulate Catabolic Factors Involved in Articular Cartilage Degradation

The Journal of biological chemistry, 2000-01, Vol.275 (2), p.721-724

2000

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Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro

Biochemical journal, 1999-11, Vol.344 Pt 1 (1), p.61-68

1999

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Expression and Activity of Articular Cartilage Hyaluronidases

Biochemical and biophysical research communications, 1998-10, Vol.251 (3), p.824-829

1998

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Variation in proteoglycan metabolism by articular chondrocytes in different joint regions is determined by post-natal mechanical loading

Osteoarthritis and cartilage, 1997, Vol.5 (1), p.49-62

1997

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Expression of ADAMTS Homologues in Articular Cartilage

Biochemical and biophysical research communications, 1999-07, Vol.260 (2), p.318-322

1999

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Products resulting from cleavage of the interglobular domain of aggrecan in samples of synovial fluid collected from dogs with early- and late-stage osteoarthritis

American journal of veterinary research, 2005-10, Vol.66 (10), p.1679-1685

2005

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Effects of n-3 fatty acids on cartilage metabolism

Proceedings of the Nutrition Society, 2002-08, Vol.61 (3), p.381-389

2002

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Differential Expression of Aggrecanase and Matrix Metalloproteinase Activity in Chondrocytes Isolated from Bovine and Porcine Articular Cartilage

The Journal of biological chemistry, 1998-11, Vol.273 (46), p.30576-30582

1998

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Pathologic indicators of degradation and inflammation in human osteoarthritic cartilage are abrogated by exposure to n‐3 fatty acids

Arthritis and rheumatism, 2002-06, Vol.46 (6), p.1544-1553

2002

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Effects of n-3 fatty acids on cartilage metabolism

Proceedings of the Nutrition Society, 2006-11, Vol.65 (4), p.434

2006

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Effects of n-3 fatty acids on cartilage metabolism

Proceedings of the Nutrition Society, 2006-12, Vol.65 (4), p.434

2006

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Cyclosporin A inhibition of aggrecanase‐mediated proteoglycan catabolism in articular cartilage

Arthritis and rheumatism, 2002-01, Vol.46 (1), p.124-129

2002

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Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro

Biochemical journal, 1999-11, Vol.344 (1), p.61-68

1999

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Expression of matrix metalloproteinases (MMPs) and disintegrin metalloproteinases (ADAMs) in experimental systems of cartilage matrix degradation

International journal of experimental pathology, 2000-02, Vol.81 (1), p.A12-A13

2000

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ADAMTS‐1–Knockout mice do not exhibit abnormalities in aggrecan turnover in vitro or in vivo

Arthritis and rheumatism, 2005-05, Vol.52 (5), p.1461-1472

2005

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IL-6 and its soluble receptor augment aggrecanase-mediated proteoglycan catabolism in articular cartilage

Matrix biology, 2000-11, Vol.19 (6), p.549-553

2000

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ADAMTS-4 and ADAMTS-5 sequestration and activity in chondrocyte-agarose cultures

International journal of experimental pathology, 2004-02, Vol.85 (1), p.A23-A24

2004

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Molecular cloning and sequence analysis of the aggrecan interglobular domain from porcine, equine, bovine and ovine cartilage: Comparison of proteinase-susceptible regions and sites of keratan sulfate substitution

Matrix biology, 1998-03, Vol.16 (8), p.507-511

1998

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Mechanisms of proteoglycan metabolism that lead to cartilage destruction in the pathogenesis of arthritis

Drugs of Today, 1999-04, Vol.35 (4-5), p.397-402

1999

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Landslides Triggered by the 14 November 2016 Mw 7.8 Kaikōura Earthquake, New Zealand

Bulletin of the Seismological Society of America, 2018-07, Vol.108 (3B), p.1630-1648

2018

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Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRASG12C Inhibitor

Journal of medicinal chemistry, 2022-11, Vol.65 (21), p.14614-14629

2022

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Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia: The CAP-IT Randomized Clinical Trial

JAMA : the journal of the American Medical Association, 2021-11, Vol.326 (17), p.1713

2021

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Activated protein C targets immune cells and rheumatoid synovial fibroblasts to prevent inflammatory arthritis in mice

Effects of culture conditions and exposure to catabolic stimulators (IL-1 and retinoic acid) on the expression of matrix metalloproteinases (MMPs) and disintegrin metalloproteinases (ADAMs) by articular cartilage chondrocytes

Mechanisms involved in cartilage proteoglycan catabolism

n-3 Fatty Acids Specifically Modulate Catabolic Factors Involved in Articular Cartilage Degradation

Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro

Expression and Activity of Articular Cartilage Hyaluronidases

Variation in proteoglycan metabolism by articular chondrocytes in different joint regions is determined by post-natal mechanical loading

Expression of ADAMTS Homologues in Articular Cartilage

Products resulting from cleavage of the interglobular domain of aggrecan in samples of synovial fluid collected from dogs with early- and late-stage osteoarthritis

Effects of n-3 fatty acids on cartilage metabolism

Differential Expression of Aggrecanase and Matrix Metalloproteinase Activity in Chondrocytes Isolated from Bovine and Porcine Articular Cartilage

Pathologic indicators of degradation and inflammation in human osteoarthritic cartilage are abrogated by exposure to n‐3 fatty acids

Effects of n-3 fatty acids on cartilage metabolism

Effects of n-3 fatty acids on cartilage metabolism

Cyclosporin A inhibition of aggrecanase‐mediated proteoglycan catabolism in articular cartilage

Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro

Expression of matrix metalloproteinases (MMPs) and disintegrin metalloproteinases (ADAMs) in experimental systems of cartilage matrix degradation

ADAMTS‐1–Knockout mice do not exhibit abnormalities in aggrecan turnover in vitro or in vivo

IL-6 and its soluble receptor augment aggrecanase-mediated proteoglycan catabolism in articular cartilage

ADAMTS-4 and ADAMTS-5 sequestration and activity in chondrocyte-agarose cultures

Molecular cloning and sequence analysis of the aggrecan interglobular domain from porcine, equine, bovine and ovine cartilage: Comparison of proteinase-susceptible regions and sites of keratan sulfate substitution

Mechanisms of proteoglycan metabolism that lead to cartilage destruction in the pathogenesis of arthritis

Landslides Triggered by the 14 November 2016 Mw 7.8 Kaikōura Earthquake, New Zealand

Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRASG12C Inhibitor

Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia: The CAP-IT Randomized Clinical Trial

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