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Intracellular Complement Activation Sustains T Cell Homeostasis and Mediates Effector Differentiation

Immunity (Cambridge, Mass.), 2013-12, Vol.39 (6), p.1143-1157

2013

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Evolution of the complement system: from defense of the single cell to guardian of the intravascular space

Immunological reviews, 2016-11, Vol.274 (1), p.9-15

2016

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Complement in Motion: The Evolution of CD46 from a Complement Regulator to an Orchestrator of Normal Cell Physiology

The Journal of immunology (1950), 2019-07, Vol.203 (1), p.3-5

2019

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The complement system in COVID-19: friend and foe?

JCI insight, 2020-08, Vol.5 (15)

2020

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Mutations in complement regulatory proteins predispose to preeclampsia: a genetic analysis of the PROMISSE cohort

PLoS medicine, 2011-03, Vol.8 (3), p.e1001013-e1001013

2011

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Complement regulator CD46: genetic variants and disease associations

Human genomics, 2015-06, Vol.9 (1), p.7-7, Article 7

2015

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Complement Dysregulation and Disease: Insights from Contemporary Genetics

Annual review of pathology, 2017-01, Vol.12, p.25

2017

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Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode

The EMBO journal, 2016-05, Vol.35 (10), p.1133-1149

2016

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West Nile Virus Nonstructural Protein NS1 Inhibits Complement Activation by binding the Regulatory Protein Factor H

Proceedings of the National Academy of Sciences - PNAS, 2006-12, Vol.103 (50), p.19111-19116

2006

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Intracellular C3 Protects Human Airway Epithelial Cells from Stress-associated Cell Death

American journal of respiratory cell and molecular biology, 2019-02, Vol.60 (2), p.144-157

2019

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Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice

The Journal of clinical investigation, 2019-03, Vol.129 (3), p.1061-1075

2019

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Dengue and the Lectin Pathway of the Complement System

Viruses, 2021-06, Vol.13 (7), p.1219

2021

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CD46 and Oncologic Interactions: Friendly Fire against Cancer

Antibodies (Basel), 2020-11, Vol.9 (4), p.59

2020

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CD46 Is a Cellular Receptor for All Species B Adenoviruses except Types 3 and 7

Journal of Virology, 2005-11, Vol.79 (22), p.14429-14436

2005

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Development and Optimization of an ELISA to Quantitate C3(H 2 O) as a Marker of Human Disease

Frontiers in immunology, 2019-04, Vol.10, p.703-703

2019

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Membrane cofactor protein (MCP; CD46): deficiency states and pathogen connections

Current opinion in immunology, 2021-10, Vol.72, p.126-134

2021

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Mutations in Human Complement Regulator, Membrane Cofactor Protein (CD46), Predispose to Development of Familial Hemolytic Uremic Syndrome

Proceedings of the National Academy of Sciences - PNAS, 2003-10, Vol.100 (22), p.12966-12971

2003

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Virulence differences between monkeypox virus isolates from West Africa and the Congo basin

Virology (New York, N.Y.), 2005-09, Vol.340 (1), p.46-63

2005

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Membrane cofactor protein mutations in atypical hemolytic uremic syndrome (aHUS), fatal Stx-HUS, C3 glomerulonephritis, and the HELLP syndrome

Blood, 2008-01, Vol.111 (2), p.624-632

2008

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Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor

The Journal of biological chemistry, 2014-01, Vol.289 (1), p.450-463

2014

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New roles for the major human 3′-5′ exonuclease TREX1 in human disease

Cell cycle (Georgetown, Tex.), 2008-06, Vol.7 (12), p.1718-1725

2008

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CD46: expanding beyond complement regulation

Trends in immunology, 2004-09, Vol.25 (9), p.496-503

2004

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Implications of the initial mutations in membrane cofactor protein (MCP; CD46) leading to atypical hemolytic uremic syndrome

Molecular immunology, 2007-01, Vol.44 (1), p.111-122

2007

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Alternative pathway activation: Ever ancient and ever new

Immunological reviews, 2023-01, Vol.313 (1), p.60-63

2023

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The complement system in COVID-19: friend and foe?

JCI insight, 2020-08, Vol.5 (15)

2020

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Intracellular Complement Activation Sustains T Cell Homeostasis and Mediates Effector Differentiation

Evolution of the complement system: from defense of the single cell to guardian of the intravascular space

Complement in Motion: The Evolution of CD46 from a Complement Regulator to an Orchestrator of Normal Cell Physiology

The complement system in COVID-19: friend and foe?

Mutations in complement regulatory proteins predispose to preeclampsia: a genetic analysis of the PROMISSE cohort

Complement regulator CD46: genetic variants and disease associations

Complement Dysregulation and Disease: Insights from Contemporary Genetics

Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode

West Nile Virus Nonstructural Protein NS1 Inhibits Complement Activation by binding the Regulatory Protein Factor H

Intracellular C3 Protects Human Airway Epithelial Cells from Stress-associated Cell Death

Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice

Dengue and the Lectin Pathway of the Complement System

CD46 and Oncologic Interactions: Friendly Fire against Cancer

CD46 Is a Cellular Receptor for All Species B Adenoviruses except Types 3 and 7

Development and Optimization of an ELISA to Quantitate C3(H 2 O) as a Marker of Human Disease

Membrane cofactor protein (MCP; CD46): deficiency states and pathogen connections

Mutations in Human Complement Regulator, Membrane Cofactor Protein (CD46), Predispose to Development of Familial Hemolytic Uremic Syndrome

Virulence differences between monkeypox virus isolates from West Africa and the Congo basin

Membrane cofactor protein mutations in atypical hemolytic uremic syndrome (aHUS), fatal Stx-HUS, C3 glomerulonephritis, and the HELLP syndrome

Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor

New roles for the major human 3′-5′ exonuclease TREX1 in human disease

CD46: expanding beyond complement regulation

Implications of the initial mutations in membrane cofactor protein (MCP; CD46) leading to atypical hemolytic uremic syndrome

Alternative pathway activation: Ever ancient and ever new

The complement system in COVID-19: friend and foe?

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