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CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis

Fibrogenesis & tissue repair, 2012-06, Vol.5 (Suppl 1), p.S24-S24, Article S24

2012

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Anti-connective tissue growth factor (CTGF/CCN2) monoclonal antibody attenuates skin fibrosis in mice models of systemic sclerosis

Arthritis research & therapy, 2017-06, Vol.19 (1), p.134-134, Article 134

2017

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Reducing CTGF/CCN2 slows down mdx muscle dystrophy and improves cell therapy

Human molecular genetics, 2013-12, Vol.22 (24), p.4938-4951

2013

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Effects of CTGF Blockade on Attenuation and Reversal of Radiation-Induced Pulmonary Fibrosis

JNCI : Journal of the National Cancer Institute, 2017-08, Vol.109 (8)

2017

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ERK1/2 directly acts on CTGF/CCN2 expression to mediate myocardial fibrosis in cardiomyopathy caused by mutations in the lamin A/C gene

Human molecular genetics, 2016-06, Vol.25 (11), p.2220-2233

2016

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Inhibition of CTGF ameliorates peritoneal fibrosis through suppression of fibroblast and myofibroblast accumulation and angiogenesis

Scientific reports, 2017-07, Vol.7 (1), p.5392-13, Article 5392

2017

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Driving fibrosis in neuromuscular diseases: Role and regulation of Connective tissue growth factor (CCN2/CTGF)

Matrix biology plus, 2021-08, Vol.11, p.100059-100059, Article 100059

2021

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Connective tissue growth factor-specific monoclonal antibody inhibits growth of malignant mesothelioma in an orthotopic mouse model

Oncotarget, 2018-04, Vol.9 (26), p.18494-18509

2018

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Anti-connective tissue growth factor antibody treatment reduces extracellular matrix production in trabecular meshwork and lamina cribrosa cells

Investigative ophthalmology & visual science, 2013-12, Vol.54 (13), p.7836-7848

2013

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Synergistic effects of crizotinib and radiotherapy in experimental EML4 – ALK fusion positive lung cancer

Radiotherapy and oncology, 2015-02, Vol.114 (2), p.173-181

2015

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Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis

The Journal of experimental medicine, 2005-03, Vol.201 (6), p.925-935

2005

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Radiation-induced pulmonary gene expression changes are attenuated by the CTGF antibody Pamrevlumab

Respiratory research, 2018-01, Vol.19 (1), p.14-14, Article 14

2018

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Connective Tissue Growth Factor Inhibition Enhances Cardiac Repair and Limits Fibrosis After Myocardial Infarction

JACC. Basic to translational science, 2019-02, Vol.4 (1), p.83-94

2019

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Combination of Vascular Endothelial Growth Factor Receptor/Platelet-Derived Growth Factor Receptor Inhibition Markedly Improves Radiation Tumor Therapy

Clinical cancer research, 2008-04, Vol.14 (7), p.2210-2219

2008

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Vascular Endothelial Cell-Specific Connective Tissue Growth Factor (CTGF) Is Necessary for Development of Chronic Hypoxia-Induced Pulmonary Hypertension

Frontiers in physiology, 2018-02, Vol.9, p.138-138

2018

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Inhibition of αvβ3 Integrin Survival Signaling Enhances Antiangiogenic and Antitumor Effects of Radiotherapy

Clinical cancer research, 2005-09, Vol.11 (17), p.6270-6279

2005

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Oncogene addiction and radiation oncology: effect of radiotherapy with photons and carbon ions in ALK-EML4 translocated NSCLC

Radiation oncology (London, England), 2018-01, Vol.13 (1), p.1-1, Article 1

2018

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Analysis of longitudinal semicontinuous data using marginalized two-part model

Journal of translational medicine, 2018-11, Vol.16 (1), p.301-301, Article 301

2018

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Role of hypoxia in skeletal muscle fibrosis: Synergism between hypoxia and TGF-β signaling upregulates CCN2/CTGF expression specifically in muscle fibers

Matrix biology, 2020-05, Vol.87, p.48-65

2020

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Comparison of human B cell activation by TLR7 and TLR9 agonists

BMC immunology, 2008-07, Vol.9 (1), p.39-39

2008

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Trimodal cancer treatment : Beneficial effects of combined antiangiogenesis, radiation, and chemotherapy

Cancer research (Chicago, Ill.), 2005-05, Vol.65 (9), p.3643-3655

2005

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The Met kinase inhibitor SU11274 exhibits a selective inhibition pattern toward different receptor mutated variants

Oncogene, 2004-07, Vol.23 (31), p.5387-5393

2004

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Mechanical stress-induced connective tissue growth factor plays a critical role in intestinal fibrosis in Crohn's-like colitis

American journal of physiology: Gastrointestinal and liver physiology, 2024-08, Vol.327 (2), p.G295-G305

2024

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Denervation-induced skeletal muscle fibrosis is mediated by CTGF/CCN2 independently of TGF-β

Matrix biology, 2019-09, Vol.82, p.20-37

2019

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CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis

Anti-connective tissue growth factor (CTGF/CCN2) monoclonal antibody attenuates skin fibrosis in mice models of systemic sclerosis

Reducing CTGF/CCN2 slows down mdx muscle dystrophy and improves cell therapy

Effects of CTGF Blockade on Attenuation and Reversal of Radiation-Induced Pulmonary Fibrosis

ERK1/2 directly acts on CTGF/CCN2 expression to mediate myocardial fibrosis in cardiomyopathy caused by mutations in the lamin A/C gene

Inhibition of CTGF ameliorates peritoneal fibrosis through suppression of fibroblast and myofibroblast accumulation and angiogenesis

Driving fibrosis in neuromuscular diseases: Role and regulation of Connective tissue growth factor (CCN2/CTGF)

Connective tissue growth factor-specific monoclonal antibody inhibits growth of malignant mesothelioma in an orthotopic mouse model

Anti-connective tissue growth factor antibody treatment reduces extracellular matrix production in trabecular meshwork and lamina cribrosa cells

Synergistic effects of crizotinib and radiotherapy in experimental EML4 – ALK fusion positive lung cancer

Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis

Radiation-induced pulmonary gene expression changes are attenuated by the CTGF antibody Pamrevlumab

Connective Tissue Growth Factor Inhibition Enhances Cardiac Repair and Limits Fibrosis After Myocardial Infarction

Combination of Vascular Endothelial Growth Factor Receptor/Platelet-Derived Growth Factor Receptor Inhibition Markedly Improves Radiation Tumor Therapy

Vascular Endothelial Cell-Specific Connective Tissue Growth Factor (CTGF) Is Necessary for Development of Chronic Hypoxia-Induced Pulmonary Hypertension

Inhibition of αvβ3 Integrin Survival Signaling Enhances Antiangiogenic and Antitumor Effects of Radiotherapy

Oncogene addiction and radiation oncology: effect of radiotherapy with photons and carbon ions in ALK-EML4 translocated NSCLC

Analysis of longitudinal semicontinuous data using marginalized two-part model

Role of hypoxia in skeletal muscle fibrosis: Synergism between hypoxia and TGF-β signaling upregulates CCN2/CTGF expression specifically in muscle fibers

Comparison of human B cell activation by TLR7 and TLR9 agonists

Trimodal cancer treatment : Beneficial effects of combined antiangiogenesis, radiation, and chemotherapy

The Met kinase inhibitor SU11274 exhibits a selective inhibition pattern toward different receptor mutated variants

Mechanical stress-induced connective tissue growth factor plays a critical role in intestinal fibrosis in Crohn's-like colitis

Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology

Denervation-induced skeletal muscle fibrosis is mediated by CTGF/CCN2 independently of TGF-β

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