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Recent developments in epigenetic cancer therapeutics: clinical advancement and emerging trends

Journal of biomedical science, 2021-04, Vol.28 (1), p.27-27, Article 27

2021

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Idiopathic Pulmonary Fibrosis: Current Status, Recent Progress, and Emerging Targets

Journal of medicinal chemistry, 2017-01, Vol.60 (2), p.527-553

2017

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Beyond the vaccines: a glance at the small molecule and peptide-based anti-COVID19 arsenal

Journal of biomedical science, 2022-09, Vol.29 (1), p.65-65, Article 65

2022

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Histone lysine specific demethylase 1 inhibitors

RSC medicinal chemistry, 2020-09, Vol.11 (9), p.969-981

2020

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Recent Update of HDAC Inhibitors in Lymphoma

Frontiers in cell and developmental biology, 2020-09, Vol.8, p.576391-576391

2020

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Effect of Sulfotyrosine and Negatively Charged Amino Acid of Leech‐Derived Peptides on Binding and Inhibitory Activity Against Thrombin

Chembiochem : a European journal of chemical biology, 2024-02, Vol.25 (3), p.e202300744-n/a

2024

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Nitro-Group-Containing Drugs

Journal of medicinal chemistry, 2019-03, Vol.62 (6), p.2851-2893

2019

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Anti-metastatic activity of MPT0G211, a novel HDAC6 inhibitor, in human breast cancer cells in vitro and in vivo

Biochimica et biophysica acta. Molecular cell research, 2019-06, Vol.1866 (6), p.992-1003

2019

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5‑Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer’s Disease Phenotypes

Journal of medicinal chemistry, 2018-08, Vol.61 (16), p.7087-7102

2018

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Hypoxia-Induced Downregulation of DUSP-2 Phosphatase Drives Colon Cancer Stemness

Cancer research (Chicago, Ill.), 2017-08, Vol.77 (16), p.4305-4316

2017

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HDAC inhibitor protects chronic cerebral hypoperfusion and oxygen‐glucose deprivation injuries via H3K14 and H4K5 acetylation‐mediated BDNF expression

Journal of cellular and molecular medicine, 2020-06, Vol.24 (12), p.6966-6977

2020

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Dual Inhibition of PIK3C3 and FGFR as a New Therapeutic Approach to Treat Bladder Cancer

Clinical cancer research, 2018-03, Vol.24 (5), p.1176-1189

2018

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Anticancer Study of a Novel Pan-HDAC Inhibitor MPT0G236 in Colorectal Cancer Cells

International journal of molecular sciences, 2023-08, Vol.24 (16), p.12588

2023

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Histone deacetylase 6 acts upstream of DNA damage response activation to support the survival of glioblastoma cells

Cell death & disease, 2021-09, Vol.12 (10), p.884-13, Article 884

2021

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Isoindoline scaffold-based dual inhibitors of HDAC6 and HSP90 suppressing the growth of lung cancer in vitro and in vivo

European journal of medicinal chemistry, 2020-03, Vol.190, p.112086-112086, Article 112086

2020

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A novel dual HDAC and HSP90 inhibitor, MPT0G449, downregulates oncogenic pathways in human acute leukemia in vitro and in vivo

Oncogenesis (New York, NY), 2021-05, Vol.10 (5), p.39-39, Article 39

2021

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The synergic effect of vincristine and vorinostat in leukemia in vitro and in vivo

Journal of hematology and oncology, 2015-07, Vol.8 (1), p.82, Article 82

2015

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Histone deacetylase inhibitor MPT0B291 suppresses Glioma Growth in vitro and in vivo partially through acetylation of p53

International journal of biological sciences, 2020-01, Vol.16 (16), p.3184-3199

2020

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3-Aroylindoles display antitumor activity in vitro and in vivo: Effects of N1-substituents on biological activity

European journal of medicinal chemistry, 2017-01, Vol.125, p.1268-1278

2017

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MPT0G612, a Novel HDAC6 Inhibitor, Induces Apoptosis and Suppresses IFN-γ-Induced Programmed Death-Ligand 1 in Human Colorectal Carcinoma Cells

Cancers, 2019-10, Vol.11 (10), p.1617

2019

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TIMP3 expression associates with prognosis in colorectal cancer and its novel arylsulfonamide inducer, MPT0B390, inhibits tumor growth, metastasis and angiogenesis

Theranostics, 2019-01, Vol.9 (22), p.6676-6689

2019

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HDAC6 involves in regulating the lncRNA-microRNA-mRNA network to promote the proliferation of glioblastoma cells

Journal of experimental & clinical cancer research, 2022-02, Vol.41 (1), p.47-47, Article 47

2022

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Effect of 3-subsitution of quinolinehydroxamic acids on selectivity of histone deacetylase isoforms

Journal of enzyme inhibition and medicinal chemistry, 2021-01, Vol.36 (1), p.74-84

2021

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Intermediary metabolite precursor dimethyl-2-ketoglutarate stabilizes hypoxia-inducible factor-1α by inhibiting prolyl-4-hydroxylase PHD2

PloS one, 2014-11, Vol.9 (11), p.e113865-e113865

2014

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MPT0B098, a Microtubule Inhibitor, Suppresses JAK2/STAT3 Signaling Pathway through Modulation of SOCS3 Stability in Oral Squamous Cell Carcinoma

PloS one, 2016-07, Vol.11 (7), p.e0158440

2016

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Recent developments in epigenetic cancer therapeutics: clinical advancement and emerging trends

Idiopathic Pulmonary Fibrosis: Current Status, Recent Progress, and Emerging Targets

Beyond the vaccines: a glance at the small molecule and peptide-based anti-COVID19 arsenal

Histone lysine specific demethylase 1 inhibitors

Recent Update of HDAC Inhibitors in Lymphoma

Effect of Sulfotyrosine and Negatively Charged Amino Acid of Leech‐Derived Peptides on Binding and Inhibitory Activity Against Thrombin

Nitro-Group-Containing Drugs

Anti-metastatic activity of MPT0G211, a novel HDAC6 inhibitor, in human breast cancer cells in vitro and in vivo

5‑Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer’s Disease Phenotypes

Hypoxia-Induced Downregulation of DUSP-2 Phosphatase Drives Colon Cancer Stemness

HDAC inhibitor protects chronic cerebral hypoperfusion and oxygen‐glucose deprivation injuries via H3K14 and H4K5 acetylation‐mediated BDNF expression

Dual Inhibition of PIK3C3 and FGFR as a New Therapeutic Approach to Treat Bladder Cancer

Anticancer Study of a Novel Pan-HDAC Inhibitor MPT0G236 in Colorectal Cancer Cells

Histone deacetylase 6 acts upstream of DNA damage response activation to support the survival of glioblastoma cells

Isoindoline scaffold-based dual inhibitors of HDAC6 and HSP90 suppressing the growth of lung cancer in vitro and in vivo

A novel dual HDAC and HSP90 inhibitor, MPT0G449, downregulates oncogenic pathways in human acute leukemia in vitro and in vivo

The synergic effect of vincristine and vorinostat in leukemia in vitro and in vivo

Histone deacetylase inhibitor MPT0B291 suppresses Glioma Growth in vitro and in vivo partially through acetylation of p53

3-Aroylindoles display antitumor activity in vitro and in vivo: Effects of N1-substituents on biological activity

MPT0G612, a Novel HDAC6 Inhibitor, Induces Apoptosis and Suppresses IFN-γ-Induced Programmed Death-Ligand 1 in Human Colorectal Carcinoma Cells

TIMP3 expression associates with prognosis in colorectal cancer and its novel arylsulfonamide inducer, MPT0B390, inhibits tumor growth, metastasis and angiogenesis

HDAC6 involves in regulating the lncRNA-microRNA-mRNA network to promote the proliferation of glioblastoma cells

Effect of 3-subsitution of quinolinehydroxamic acids on selectivity of histone deacetylase isoforms

Intermediary metabolite precursor dimethyl-2-ketoglutarate stabilizes hypoxia-inducible factor-1α by inhibiting prolyl-4-hydroxylase PHD2

MPT0B098, a Microtubule Inhibitor, Suppresses JAK2/STAT3 Signaling Pathway through Modulation of SOCS3 Stability in Oral Squamous Cell Carcinoma

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