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Synthesis and Antiviral Activity of a Series of 2'- C -Methyl-4'-thionucleoside Monophosphate Prodrugs

Molecules (Basel, Switzerland), 2020-11, Vol.25 (21), p.5165

2020

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GluN2D-Containing N-methyl-d-Aspartate Receptors Mediate Synaptic Transmission in Hippocampal Interneurons and Regulate Interneuron Activity

Molecular pharmacology, 2016-12, Vol.90 (6), p.689-702

2016

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Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors

Nature communications, 2019-01, Vol.10 (1), p.321-321, Article 321

2019

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Thematic Review Series: Sphingolipids. Biodiversity of sphingoid bases (“sphingosines”) and related amino alcohols

Journal of lipid research, 2008-08, Vol.49 (8), p.1621-1639

2008

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Context-Dependent GluN2B-Selective Inhibitors of NMDA Receptor Function Are Neuroprotective with Minimal Side Effects

Neuron (Cambridge, Mass.), 2015-03, Vol.85 (6), p.1305-1318

2015

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Development of a unique small molecule modulator of CXCR4

PloS one, 2012-04, Vol.7 (4), p.e34038

2012

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Reduction Sensitive Lipid Conjugates of Tenofovir: Synthesis, Stability, and Antiviral Activity

Journal of medicinal chemistry, 2016-08, Vol.59 (15), p.7097-7110

2016

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Polyoxometalate HIV-1 Protease Inhibitors. A New Mode of Protease Inhibition

Journal of the American Chemical Society, 2001-02, Vol.123 (5), p.886-897

2001

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Recent advances in the development of HBV capsid assembly modulators

Current opinion in chemical biology, 2019-06, Vol.50, p.73-79

2019

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Asymmetric Hydrogenation and Catalyst Recycling Using Ionic Liquid and Supercritical Carbon Dioxide

Journal of the American Chemical Society, 2001-02, Vol.123 (6), p.1254-1255

2001

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Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents

Bioorganic & medicinal chemistry, 2004-07, Vol.12 (14), p.3871-3883

2004

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A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors

Nature communications, 2010-10, Vol.1 (7), p.1-8, Article 90

2010

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CCR5 receptor antagonists in preclinical to phase II clinical development for treatment of HIV

Expert opinion on investigational drugs, 2016-12, Vol.25 (12), p.1377-1392

2016

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Prebiotic Phosphorylation of Uridine using Diamidophosphate in Aerosols

Scientific reports, 2019-09, Vol.9 (1), p.13527-8, Article 13527

2019

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An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups

eLife, 2018-05, Vol.7

2018

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Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators

Molecular pharmacology, 2011-11, Vol.80 (5), p.782-795

2011

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Expanding the toolbox of metabolically stable lipid prodrug strategies

Frontiers in pharmacology, 2023-01, Vol.13, p.1083284-1083284

2023

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Quinazolin-4-one Derivatives: A Novel Class of Noncompetitive NR2C/D Subunit-Selective N-Methyl-d-aspartate Receptor Antagonists

Journal of medicinal chemistry, 2010-08, Vol.53 (15), p.5476-5490

2010

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EF24, a novel synthetic curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism

Anti-cancer drugs, 2005-03, Vol.16 (3), p.263-275

2005

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Structural analysis of CXCR4 – Antagonist interactions using saturation-transfer double-difference NMR

Biochemical and biophysical research communications, 2015-10, Vol.466 (1), p.28-32

2015

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Curcumin analog cytotoxicity against breast cancer cells: exploitation of a redox-dependent mechanism

Bioorganic & medicinal chemistry letters, 2009-12, Vol.19 (23), p.6627-6631

2009

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Journal of Medicinal Chemistry/ACS Medicinal Chemistry Letters/Division of Medicinal Chemistry Joint Portoghese Lectureship Awards: CALL FOR NOMINATIONS

Journal of medicinal chemistry, 2022-02, Vol.65 (3), p.1610-1611

2022

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Chloride is an Agonist of Group II and III Metabotropic Glutamate Receptors

Molecular pharmacology, 2015-09, Vol.88 (3), p.450-459

2015

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Discovery and Development of the Anti-Human Immunodeficiency Virus Drug, Emtricitabine (Emtriva, FTC)

Accounts of chemical research, 2016-10, Vol.49 (10), p.2091-2098

2016

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A Virtual Collection Focused on Antifungal Drug Discovery

Journal of medicinal chemistry, 2022-02, Vol.65 (4), p.2988-2988

2022

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Synthesis and Antiviral Activity of a Series of 2'- C -Methyl-4'-thionucleoside Monophosphate Prodrugs

GluN2D-Containing N-methyl-d-Aspartate Receptors Mediate Synaptic Transmission in Hippocampal Interneurons and Regulate Interneuron Activity

Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors

Thematic Review Series: Sphingolipids. Biodiversity of sphingoid bases (“sphingosines”) and related amino alcohols

Context-Dependent GluN2B-Selective Inhibitors of NMDA Receptor Function Are Neuroprotective with Minimal Side Effects

Development of a unique small molecule modulator of CXCR4

Reduction Sensitive Lipid Conjugates of Tenofovir: Synthesis, Stability, and Antiviral Activity

Polyoxometalate HIV-1 Protease Inhibitors. A New Mode of Protease Inhibition

Recent advances in the development of HBV capsid assembly modulators

Asymmetric Hydrogenation and Catalyst Recycling Using Ionic Liquid and Supercritical Carbon Dioxide

Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents

A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors

CCR5 receptor antagonists in preclinical to phase II clinical development for treatment of HIV

Prebiotic Phosphorylation of Uridine using Diamidophosphate in Aerosols

An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups

Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators

Expanding the toolbox of metabolically stable lipid prodrug strategies

Quinazolin-4-one Derivatives: A Novel Class of Noncompetitive NR2C/D Subunit-Selective N-Methyl-d-aspartate Receptor Antagonists

EF24, a novel synthetic curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism

Structural analysis of CXCR4 – Antagonist interactions using saturation-transfer double-difference NMR

Curcumin analog cytotoxicity against breast cancer cells: exploitation of a redox-dependent mechanism

Journal of Medicinal Chemistry/ACS Medicinal Chemistry Letters/Division of Medicinal Chemistry Joint Portoghese Lectureship Awards: CALL FOR NOMINATIONS

Chloride is an Agonist of Group II and III Metabotropic Glutamate Receptors

Discovery and Development of the Anti-Human Immunodeficiency Virus Drug, Emtricitabine (Emtriva, FTC)

A Virtual Collection Focused on Antifungal Drug Discovery

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