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Droplet microfluidic technology for single-cell high-throughput screening

Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (34), p.14195-14200

2009

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Multiplex picodroplet digital PCR to detect KRAS mutations in circulating DNA from the plasma of colorectal cancer patients

Clinical chemistry (Baltimore, Md.), 2013-12, Vol.59 (12), p.1722-1731

2013

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Multiplex digital PCR: breaking the one target per color barrier of quantitative PCR

Lab on a chip, 2011-01, Vol.11 (13), p.2167-2174

2011

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Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity

Lab on a chip, 2009-01, Vol.9 (13), p.1850-1858

2009

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High-resolution dose—response screening using droplet-based microfluidics

Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (2), p.378-383

2012

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A Study of Hypermethylated Circulating Tumor DNA as a Universal Colorectal Cancer Biomarker

Clinical chemistry (Baltimore, Md.), 2016-08, Vol.62 (8), p.1129-1139

2016

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Electric Control of Droplets in Microfluidic Devices

Angewandte Chemie (International ed.), 2006-04, Vol.45 (16), p.2556-2560

2006

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Quantitative and sensitive detection of rare mutations using droplet-based microfluidics

Lab on a chip, 2011-07, Vol.11 (13), p.2156-2166

2011

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Dynamic regulation of HIV-1 mRNA populations analyzed by single-molecule enrichment and long-read sequencing

Nucleic acids research, 2012-11, Vol.40 (20), p.10345-10355

2012

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High-Throughput Quantitative Polymerase Chain Reaction in Picoliter Droplets

Analytical chemistry (Washington), 2008-12, Vol.80 (23), p.8975-8981

2008

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Detection and Analysis of Low-Abundance Cell-Surface Biomarkers Using Enzymatic Amplification in Microfluidic Droplets

Angewandte Chemie (International ed.), 2009-01, Vol.48 (14), p.2518-2521

2009

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Control and Measurement of the Phase Behavior of Aqueous Solutions Using Microfluidics

Journal of the American Chemical Society, 2007-07, Vol.129 (28), p.8825-8835

2007

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Circulating tumor DNA is a prognostic marker of tumor recurrence in stage II and III colorectal cancer: multicentric, prospective cohort study (ALGECOLS)

European journal of cancer (1990), 2021-12, Vol.159, p.24-33

2021

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Clinical relevance of KRAS-mutated subclones detected with picodroplet digital PCR in advanced colorectal cancer treated with anti-EGFR therapy

Clinical cancer research, 2015-03, Vol.21 (5), p.1087-1097

2015

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Multiplex picoliter-droplet digital PCR for quantitative assessment of DNA integrity in clinical samples

Clinical chemistry (Baltimore, Md.), 2013-05, Vol.59 (5), p.815-823

2013

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Determining lower limits of detection of digital PCR assays for cancer-related gene mutations

Biomolecular detection and quantification, 2014-09, Vol.1 (1), p.8-22

2014

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Microdroplet-based PCR enrichment for large-scale targeted sequencing

Nature biotechnology, 2009-11, Vol.27 (11), p.1025-1031

2009

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Microfluidic Assembly of Homogeneous and Janus Colloid-Filled Hydrogel Granules

Langmuir, 2006-10, Vol.22 (21), p.8618-8622

2006

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Detection of low prevalence somatic mutations in solid tumors with ultra-deep targeted sequencing

Genome biology, 2011-12, Vol.12 (12), p.R124-R124, Article R124

2011

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Generation of Polymerosomes from Double-Emulsions

Langmuir, 2005-09, Vol.21 (20), p.9183-9186

2005

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Droplet-Based Microfluidic Systems for High-Throughput Single DNA Molecule Isothermal Amplification and Analysis

Analytical chemistry (Washington), 2009-06, Vol.81 (12), p.4813-4821

2009

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Controlled production of emulsion drops using an electric field in a flow-focusing microfluidic device

Applied physics letters, 2007-09, Vol.91 (13)

2007

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Using Microfluidics to Decouple Nucleation and Growth of Protein Crystals

Crystal growth & design, 2007-11, Vol.7 (11), p.2192-2194

2007

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Spontaneous Formation of Macroscopic Chiral Domains in a Fluid Smectic Phase of Achiral Molecules

Science (American Association for the Advancement of Science), 1997-12, Vol.278 (5345), p.1924-1927

1997

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Accurate variant detection across non-amplified and whole genome amplified DNA using targeted next generation sequencing

BMC genomics, 2012-09, Vol.13 (1), p.500-500, Article 500

2012

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Droplet microfluidic technology for single-cell high-throughput screening

Multiplex picodroplet digital PCR to detect KRAS mutations in circulating DNA from the plasma of colorectal cancer patients

Multiplex digital PCR: breaking the one target per color barrier of quantitative PCR

Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity

High-resolution dose—response screening using droplet-based microfluidics

A Study of Hypermethylated Circulating Tumor DNA as a Universal Colorectal Cancer Biomarker

Electric Control of Droplets in Microfluidic Devices

Quantitative and sensitive detection of rare mutations using droplet-based microfluidics

Dynamic regulation of HIV-1 mRNA populations analyzed by single-molecule enrichment and long-read sequencing

High-Throughput Quantitative Polymerase Chain Reaction in Picoliter Droplets

Detection and Analysis of Low-Abundance Cell-Surface Biomarkers Using Enzymatic Amplification in Microfluidic Droplets

Control and Measurement of the Phase Behavior of Aqueous Solutions Using Microfluidics

Circulating tumor DNA is a prognostic marker of tumor recurrence in stage II and III colorectal cancer: multicentric, prospective cohort study (ALGECOLS)

Clinical relevance of KRAS-mutated subclones detected with picodroplet digital PCR in advanced colorectal cancer treated with anti-EGFR therapy

Multiplex picoliter-droplet digital PCR for quantitative assessment of DNA integrity in clinical samples

Determining lower limits of detection of digital PCR assays for cancer-related gene mutations

Microdroplet-based PCR enrichment for large-scale targeted sequencing

Microfluidic Assembly of Homogeneous and Janus Colloid-Filled Hydrogel Granules

Detection of low prevalence somatic mutations in solid tumors with ultra-deep targeted sequencing

Generation of Polymerosomes from Double-Emulsions

Droplet-Based Microfluidic Systems for High-Throughput Single DNA Molecule Isothermal Amplification and Analysis

Controlled production of emulsion drops using an electric field in a flow-focusing microfluidic device

Using Microfluidics to Decouple Nucleation and Growth of Protein Crystals

Spontaneous Formation of Macroscopic Chiral Domains in a Fluid Smectic Phase of Achiral Molecules

Accurate variant detection across non-amplified and whole genome amplified DNA using targeted next generation sequencing

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