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A common glycan structure on immunoglobulin G for enhancement of effector functions

Proceedings of the National Academy of Sciences - PNAS, 2015-08, Vol.112 (34), p.10611-10616

2015

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Highly Alpha-Selective Sialyl Phosphate Donors for Efficient Preparation of Natural Sialosides

Chemistry : a European journal, 2010-02, Vol.16 (6), p.1754-1760

2010

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Modular synthesis of N-glycans and arrays for the hetero-ligand binding analysis of HIV antibodies

Nature chemistry, 2016-04, Vol.8 (4), p.338-346

2016

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Design and Synthesis of Active Site Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Apoptosis and Inhibition of ERK Phosphorylation in Multiple Myeloma Cells

Journal of medicinal chemistry, 2012-04, Vol.55 (7), p.3201-3215

2012

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Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase

PloS one, 2017-10, Vol.12 (10), p.e0186447-e0186447

2017

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Modular Assembly of Purine-like Bisphosphonates as Inhibitors of HIV‑1 Reverse Transcriptase

Journal of medicinal chemistry, 2014-09, Vol.57 (17), p.7435-7449

2014

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Development of Furanopyrimidine-Based Orally Active Third-Generation EGFR Inhibitors for the Treatment of Non-Small Cell Lung Cancer

Journal of medicinal chemistry, 2023-02, Vol.66 (4), p.2566-2588

2023

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PROGRESS IN DEVELOPING A LIGHT‐STABLE 4R TAU PET IMAGING AGENT: APN‐1701 FIH

Alzheimer's & dementia, 2022-12, Vol.18 (S1), p.n/a

2022

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Targeting the Delivery of Glycan-Based Paclitaxel Prodrugs to Cancer Cells via Glucose Transporters

Journal of medicinal chemistry, 2008-12, Vol.51 (23), p.7428-7441

2008

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Multistage Screening Reveals Chameleon Ligands of the Human Farnesyl Pyrophosphate Synthase: Implications to Drug Discovery for Neurodegenerative Diseases

Journal of medicinal chemistry, 2014-07, Vol.57 (13), p.5764-5776

2014

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Structure of human farnesyl pyrophosphate synthase in complex with an aminopyridine bisphosphonate and two molecules of inorganic phosphate

Acta crystallographica. Section F, Structural biology communications, 2014-03, Vol.70 (3), p.299-304

2014

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Discovery of novel inhibitors of Aurora kinases with indazole scaffold: In silico fragment-based and knowledge-based drug design

European journal of medicinal chemistry, 2016-11, Vol.124, p.186-199

2016

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Design of potent bisphosphonate inhibitors of the human farnesyl pyrophosphate synthase via targeted interactions with the active site ‘capping’ phenyls

Bioorganic & medicinal chemistry, 2012-09, Vol.20 (18), p.5583-5591

2012

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Probing the molecular and structural elements of ligands binding to the active site versus an allosteric pocket of the human farnesyl pyrophosphate synthase

Bioorganic & medicinal chemistry letters, 2015-03, Vol.25 (5), p.1117-1123

2015

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Breast Tumor Microenvironment: Proteomics Highlights the Treatments Targeting Secretome

Journal of proteome research, 2008-04, Vol.7 (4), p.1379-1387

2008

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Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure

BMC structural biology, 2012-12, Vol.12 (1), p.32-32, Article 32

2012

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Discovery of a‐synuclein degraders as potential therapeutics for Parkinson's disease

Alzheimer's & dementia, 2021-12, Vol.17 (S9), p.n/a

2021

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IN‐VIVO EVALUATION OF APN‐1808, A TAU SMALL MOLECULE THERAPEUTIC

Alzheimer's & dementia, 2022-12, Vol.18 (S10), p.n/a

2022

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PROTAC tau degrader for the treatment of Alzheimer’s disease and primary tauopathies

Alzheimer's & dementia, 2023-12, Vol.19 (S21), p.n/a

2023

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PROGRESS IN DEVELOPING A LIGHT‐STABLE 4R TAU PET IMAGING AGENT: APN‐1701 FIH

Alzheimer's & dementia, 2022-12, Vol.18 (S6), p.n/a

2022

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P4‐037: APRINOIA THERAPEUTIC'S SMALL MOLECULE DISCOVERY PLATFORM: USING [18F]‐APN‐1607 FOR TARGET ENGAGEMENT STUDIES WITH SMALL MOLECULE THERAPEUTICS

Alzheimer's & dementia, 2019-07, Vol.15 (7S_Part_24), p.P1288-P1288

2019

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APRINOIA THERAPEUTIC'S SMALL MOLECULE DISCOVERY PLATFORM: USING [18F]-APN-1607 FOR TARGET ENGAGEMENT STUDIES WITH SMALL MOLECULE THERAPEUTICS

Alzheimer's & dementia, 2019-07, Vol.15 (7), p.P1288-P1288

2019

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Crystal structures of hFPPS in complex with novel anticancer drug leads

Acta crystallographica. Section A, Foundations and advances, 2014-08, Vol.70 (a1), p.C712-C712

2014

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Gibberellic Acid and Cytokinin Affect Phalaenopsis Flower Morphology at High Temperature

HortScience, 1997-10, Vol.32 (6), p.1069-1073

1997

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Targeting the Delivery of Glycan-Based Paclitaxel Prodrugs to Cancer Cells via Glucose Transporters

Journal of medicinal chemistry, 2009-02, Vol.52 (3), p.889-889

2009

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A common glycan structure on immunoglobulin G for enhancement of effector functions

Highly Alpha-Selective Sialyl Phosphate Donors for Efficient Preparation of Natural Sialosides

Modular synthesis of N-glycans and arrays for the hetero-ligand binding analysis of HIV antibodies

Design and Synthesis of Active Site Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Apoptosis and Inhibition of ERK Phosphorylation in Multiple Myeloma Cells

Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase

Modular Assembly of Purine-like Bisphosphonates as Inhibitors of HIV‑1 Reverse Transcriptase

Development of Furanopyrimidine-Based Orally Active Third-Generation EGFR Inhibitors for the Treatment of Non-Small Cell Lung Cancer

PROGRESS IN DEVELOPING A LIGHT‐STABLE 4R TAU PET IMAGING AGENT: APN‐1701 FIH

Targeting the Delivery of Glycan-Based Paclitaxel Prodrugs to Cancer Cells via Glucose Transporters

Multistage Screening Reveals Chameleon Ligands of the Human Farnesyl Pyrophosphate Synthase: Implications to Drug Discovery for Neurodegenerative Diseases

Structure of human farnesyl pyrophosphate synthase in complex with an aminopyridine bisphosphonate and two molecules of inorganic phosphate

Discovery of novel inhibitors of Aurora kinases with indazole scaffold: In silico fragment-based and knowledge-based drug design

Design of potent bisphosphonate inhibitors of the human farnesyl pyrophosphate synthase via targeted interactions with the active site ‘capping’ phenyls

Probing the molecular and structural elements of ligands binding to the active site versus an allosteric pocket of the human farnesyl pyrophosphate synthase

Breast Tumor Microenvironment: Proteomics Highlights the Treatments Targeting Secretome

Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure

Discovery of a‐synuclein degraders as potential therapeutics for Parkinson's disease

IN‐VIVO EVALUATION OF APN‐1808, A TAU SMALL MOLECULE THERAPEUTIC

PROTAC tau degrader for the treatment of Alzheimer’s disease and primary tauopathies

PROGRESS IN DEVELOPING A LIGHT‐STABLE 4R TAU PET IMAGING AGENT: APN‐1701 FIH

P4‐037: APRINOIA THERAPEUTIC'S SMALL MOLECULE DISCOVERY PLATFORM: USING [18F]‐APN‐1607 FOR TARGET ENGAGEMENT STUDIES WITH SMALL MOLECULE THERAPEUTICS

APRINOIA THERAPEUTIC'S SMALL MOLECULE DISCOVERY PLATFORM: USING [18F]-APN-1607 FOR TARGET ENGAGEMENT STUDIES WITH SMALL MOLECULE THERAPEUTICS

Crystal structures of hFPPS in complex with novel anticancer drug leads

Gibberellic Acid and Cytokinin Affect Phalaenopsis Flower Morphology at High Temperature

Targeting the Delivery of Glycan-Based Paclitaxel Prodrugs to Cancer Cells via Glucose Transporters

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