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Pharmacokinetics and Pharmacodynamics of LCZ696, a Novel Dual-Acting Angiotensin Receptor-Neprilysin Inhibitor (ARNi)

Journal of clinical pharmacology, 2010-04, Vol.50 (4), p.401-414

2010

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Unsymmetrical Squaraines Incorporating the Thiophene Unit for Panchromatic Dye-Sensitized Solar Cells

Organic letters, 2010-12, Vol.12 (23), p.5454-5457

2010

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Nilotinib preclinical pharmacokinetics and practical application toward clinical projections of oral absorption and systemic availability

Biopharmaceutics & drug disposition, 2012-12, Vol.33 (9), p.536-549

2012

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Pharmacokinetics and safety of sacubitril/valsartan (LCZ696) in patients with mild and moderate hepatic impairment

International journal of clinical pharmacology and therapeutics, 2017-09, Vol.55 (9), p.728

2017

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Utility of Physiologically Based Modeling and Preclinical In Vitro/In Vivo Data to Mitigate Positive Food Effect in a BCS Class 2 Compound

AAPS PharmSciTech, 2013-09, Vol.14 (3), p.1255-1266

2013

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Case Studies for Practical Food Effect Assessments across BCS/BDDCS Class Compounds using In Silico, In Vitro, and Preclinical In Vivo Data

The AAPS journal, 2013-01, Vol.15 (1), p.143-158

2013

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Evaluation of Drug-Drug Interaction Potential Between Sacubitril/Valsartan (LCZ696) and Statins Using a Physiologically Based Pharmacokinetic Model

Journal of pharmaceutical sciences, 2017-05, Vol.106 (5), p.1439-1451

2017

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Effects of hepatic impairment on the pharmacokinetics of nilotinib: An open-label, single-dose, parallel-group study

Clinical therapeutics, 2009, Vol.31, p.2459-2469

2009

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Osilodrostat (LCI699), a potent 11β-hydroxylase inhibitor, administered in combination with the multireceptor-targeted somatostatin analog pasireotide: A 13-week study in rats

Toxicology and applied pharmacology, 2015-08, Vol.286 (3), p.224-233

2015

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Application of Physiologically Based Absorption Modeling to Formulation Development of a Low Solubility, Low Permeability Weak Base: Mechanistic Investigation of Food Effect

AAPS PharmSciTech, 2014-04, Vol.15 (2), p.400-406

2014

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Unsymmetrical Squaraines Incorporating Cabazole as a Donor for Dye-Sensitized Solar Cells

Journal of the Chinese Chemical Society (Taipei), 2012-10, Vol.59 (10), p.1337-1344

2012

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Novel physiologically based pharmacokinetic modeling of patupilone for human pharmacokinetic predictions

Cancer chemotherapy and pharmacology, 2012-06, Vol.69 (6), p.1567-1582

2012

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9cUAB30, an RXR specific retinoid, and/or tamoxifen in the prevention of methylnitrosourea-induced mammary cancers

Cancer letters, 2003-11, Vol.201 (1), p.17-24

2003

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A fully integrated closed-loop neuromodulation SoC with wireless power and bi-directional data telemetry for real-time human epileptic seizure control

2017 Symposium on VLSI Circuits, 2017, p.C44-C45

2017

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A bone-guided cochlear implant CMOS microsystem preserving acoustic hearing

2017 Symposium on VLSI Circuits, 2017, p.C46-C47

2017

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Nonenzymatic isomerization of 9-cis-retinoic acid catalyzed by sulfhydryl compounds

Drug metabolism and disposition, 1997-01, Vol.25 (1), p.27

1997

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Effect of Renal Impairment on the Pharmacokinetics of Pradigastat, a Novel Diacylglycerol Acyltransferase1 (DGAT1) Inhibitor

Clinical pharmacokinetics, 2015-07, Vol.54 (7), p.751-760

2015

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Effect of Hepatic Impairment on the Pharmacokinetics of Pradigastat, a Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitor

Clinical pharmacokinetics, 2015-07, Vol.54 (7), p.761-770

2015

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Inhibition of blood-brain barrier permeability to dl-propranolol by serum from acute renal failure rats

Biochemical pharmacology, 1987-10, Vol.36 (20), p.3425-3431

1987

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Effects of Albumin and α1-Acid Glycoprotein on the Transport of Imipramine and Desipramine through the Blood-Brain Barrier in Rats

Chemical and Pharmaceutical Bulletin, 1987/01/25, Vol.35(1), pp.294-301

1987

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Effect of phenobarbitone on the distribution and elimination of imipramine in rats

Journal of pharmacy and pharmacology, 1985-10, Vol.37 (10), p.735-738

1985

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Albumin-mediated transport phenomenon' observed for ligands with high membrane permeability : effect of the unstirred water layer in the Disse's space of rat liver

Journal of hepatology, 1992-09, Vol.16 (1-2), p.38-49

1992

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Uptake and stereoselective binding of the enantiomers of MK-927, a potent carbonic anhydrase inhibitor, by human erythrocytes in vitro

Pharmaceutical research, 1992-03, Vol.9 (3), p.339-344

1992

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Murine Toxicology and Pharmacology of UAB-8, a Conformationally Constrained Analog of Retinoic Acid

Toxicology and applied pharmacology, 1996-08, Vol.139 (2), p.310-316

1996

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Effects of Hepatic Impairment on the Pharmacokinetics of Nilotinib: An Open-Label, Single-Dose, Parallel-Group Study: Oncology-Standard & Targeted Therapies

Clinical therapeutics, 2009, Vol.31 (THEM), p.2459-2469

2009

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Pharmacokinetics and Pharmacodynamics of LCZ696, a Novel Dual-Acting Angiotensin Receptor-Neprilysin Inhibitor (ARNi)

Unsymmetrical Squaraines Incorporating the Thiophene Unit for Panchromatic Dye-Sensitized Solar Cells

Nilotinib preclinical pharmacokinetics and practical application toward clinical projections of oral absorption and systemic availability

Pharmacokinetics and safety of sacubitril/valsartan (LCZ696) in patients with mild and moderate hepatic impairment

Utility of Physiologically Based Modeling and Preclinical In Vitro/In Vivo Data to Mitigate Positive Food Effect in a BCS Class 2 Compound

Case Studies for Practical Food Effect Assessments across BCS/BDDCS Class Compounds using In Silico, In Vitro, and Preclinical In Vivo Data

Evaluation of Drug-Drug Interaction Potential Between Sacubitril/Valsartan (LCZ696) and Statins Using a Physiologically Based Pharmacokinetic Model

Effects of hepatic impairment on the pharmacokinetics of nilotinib: An open-label, single-dose, parallel-group study

Osilodrostat (LCI699), a potent 11β-hydroxylase inhibitor, administered in combination with the multireceptor-targeted somatostatin analog pasireotide: A 13-week study in rats

Application of Physiologically Based Absorption Modeling to Formulation Development of a Low Solubility, Low Permeability Weak Base: Mechanistic Investigation of Food Effect

Unsymmetrical Squaraines Incorporating Cabazole as a Donor for Dye-Sensitized Solar Cells

Novel physiologically based pharmacokinetic modeling of patupilone for human pharmacokinetic predictions

9cUAB30, an RXR specific retinoid, and/or tamoxifen in the prevention of methylnitrosourea-induced mammary cancers

A fully integrated closed-loop neuromodulation SoC with wireless power and bi-directional data telemetry for real-time human epileptic seizure control

A bone-guided cochlear implant CMOS microsystem preserving acoustic hearing

Nonenzymatic isomerization of 9-cis-retinoic acid catalyzed by sulfhydryl compounds

Effect of Renal Impairment on the Pharmacokinetics of Pradigastat, a Novel Diacylglycerol Acyltransferase1 (DGAT1) Inhibitor

Effect of Hepatic Impairment on the Pharmacokinetics of Pradigastat, a Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitor

Inhibition of blood-brain barrier permeability to dl-propranolol by serum from acute renal failure rats

Effects of Albumin and α1-Acid Glycoprotein on the Transport of Imipramine and Desipramine through the Blood-Brain Barrier in Rats

Effect of phenobarbitone on the distribution and elimination of imipramine in rats

Albumin-mediated transport phenomenon' observed for ligands with high membrane permeability : effect of the unstirred water layer in the Disse's space of rat liver

Uptake and stereoselective binding of the enantiomers of MK-927, a potent carbonic anhydrase inhibitor, by human erythrocytes in vitro

Murine Toxicology and Pharmacology of UAB-8, a Conformationally Constrained Analog of Retinoic Acid

Effects of Hepatic Impairment on the Pharmacokinetics of Nilotinib: An Open-Label, Single-Dose, Parallel-Group Study: Oncology-Standard & Targeted Therapies

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