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Structural and Functional Analysis of HtrA1 and Its Subdomains

Structure (London), 2012-06, Vol.20 (6), p.1040-1050

2012

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Design of a Selective Substrate and Activity Based Probe for Human Neutrophil Serine Protease 4

PloS one, 2015-07, Vol.10 (7), p.e0132818-e0132818

2015

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Structures of Neutrophil Serine Protease 4 Reveal an Unusual Mechanism of Substrate Recognition by a Trypsin-Fold Protease

Structure (London), 2014-09, Vol.22 (9), p.1333-1340

2014

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Structure of betaglycan zona pellucida (ZP)-C domain provides insights into ZP-mediated protein polymerization and TGF-β binding

Proceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (13), p.5232-5236

2011

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Proteolytic activation of pro-macrophage-stimulating protein by hepsin

Molecular cancer research, 2011-09, Vol.9 (9), p.1175-1186

2011

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The structural basis of TGF-β, bone morphogenetic protein, and activin ligand binding

Reproduction (Cambridge, England), 2006-08, Vol.132 (2), p.179-190

2006

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867 TriTAC-XR is an extended-release T cell engager platform designed to minimize cytokine release syndrome by reducing Cmax in systemic circulation

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A908-A908

2021

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Neutrophil serine protease 4 is required for mast cell-dependent vascular leakage

Communications biology, 2020-11, Vol.3 (1), p.687-687, Article 687

2020

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An ancient mechanism of arginine-specific substrate cleavage: What's ‘up’ with NSP4?

Biochimie, 2019-11, Vol.166, p.19-26

2019

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Furin-cleaved Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Is Active and Modulates Low Density Lipoprotein Receptor and Serum Cholesterol Levels

The Journal of biological chemistry, 2012-12, Vol.287 (52), p.43482-43491

2012

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Inhibin α-Subunit N Terminus Interacts with Activin Type IB Receptor to Disrupt Activin Signaling

The Journal of biological chemistry, 2012-03, Vol.287 (11), p.8060-8070

2012

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An allosteric anti-hepsin antibody derived from a constrained phage display library

Protein engineering, design and selection, 2012-03, Vol.25 (3), p.127-133

2012

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Phylogenomic Analyses Reveal the Evolutionary Origin of the Inhibin α-Subunit, a Unique TGFβ Superfamily Antagonist

PloS one, 2010-03, Vol.5 (3), p.e9457

2010

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Abstract 933: ProTriTAC is a modular and robust T cell engager prodrug platform with therapeutic index expansion observed across multiple tumor targets

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.933-933

2021

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Phylogenomic analyses reveal the evolutionary origin of the inhibin alpha-subunit, a unique TGFbeta superfamily antagonist

PloS one, 2010-03, Vol.5 (3), p.e9457-e9457

2010

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Novel staphylococcal glycosyltransferases SdgA and SdgB mediate immunogenicity and protection of virulence-associated cell wall proteins

PLoS pathogens, 2013-10, Vol.9 (10), p.e1003653-e1003653

2013

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Abstract 5070: Anti-tumor activity of HPN328, a DLL3-targeting tri-specific, half-life extended T cell engager, is enhanced by combining with an anti-PD-L1 antibody in an immunocompetent mouse model

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.5070-5070

2023

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Abstract 2927: ITGB6 ProTriTAC™, a protease-activated T cell engager prodrug targeting Integrin-β6 for the treatment of solid tumors

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.2927-2927

2023

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Abstract 2928: TROP2 ProTriTAC™, a protease-activated T cell engager prodrug targeting TROP2 for the treatment of solid tumors

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.2928-2928

2023

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Coupling-Aware Functional Timing Analysis for Tighter Bounds: How Much Margin Can We Relax?

Proceedings of the Great Lakes Symposium on VLSI 2017, 2017, p.251-256

2017

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Abstract 2861: TriTAC-XR: An extended-release T cell engager platform designed to minimize cytokine release syndrome

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.2861-2861

2022

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Structure of betaglycan zona pellucida (ZP)-C domain provides insights into ZP-mediated protein polymerization and TGF-[Beta] binding

Proceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (13), p.5232

2011

Volltextzugriff (PDF)

Structure of betaglycan zona pellucida (ZP)-C domain provides insights into ZP-mediated protein polymerization and TGF-Î² binding

Proceedings of the National Academy of Sciences - PNAS, 2011, Vol.108 (13), p.5232-5236

2011

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Design of a Selective Substrate and Activity Based Probe for Human Neutrophil Serine Protease 4: e0132818

PloS one, 2015-07, Vol.10 (7)

2015

Volltextzugriff (PDF)

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