UB Paderborn / Katalog / Suche / in CDI

Development of glycosynthases with broad glycan specificity for the efficient glyco-remodeling of antibodies

Chemical communications (Cambridge, England), 2018, Vol.54 (48), p.6161-6164

2018

Volltextzugriff (PDF)

An Effective Bacterial Fucosidase for Glycoprotein Remodeling

ACS chemical biology, 2017-01, Vol.12 (1), p.63-72

2017

Volltextzugriff (PDF)

Selective Chk1 inhibitors differentially sensitize p53‐deficient cancer cells to cancer therapeutics

International journal of cancer, 2006-12, Vol.119 (12), p.2784-2794

2006

Volltextzugriff (PDF)

Chk1 inhibitors for novel cancer treatment

Anti-cancer agents in medicinal chemistry, 2006-07, Vol.6 (4), p.377

2006

Volltextzugriff (PDF)

A common glycan structure on immunoglobulin G for enhancement of effector functions

Proceedings of the National Academy of Sciences - PNAS, 2015-08, Vol.112 (34), p.10611-10616

2015

Volltextzugriff (PDF)

Structure-Based Design, Synthesis, and Biological Evaluation of Potent and Selective Macrocyclic Checkpoint Kinase 1 Inhibitors

Journal of medicinal chemistry, 2007-04, Vol.50 (7), p.1514-1527

2007

Volltextzugriff (PDF)

Unprecedented Role of Hybrid N-Glycans as Ligands for HIV‑1 Broadly Neutralizing Antibodies

Journal of the American Chemical Society, 2018-04, Vol.140 (15), p.5202-5210

2018

Volltextzugriff (PDF)

Design, Synthesis, and Biological Activity of 5,10-Dihydro-dibenzo[b,e][1,4]diazepin-11-one-Based Potent and Selective Chk-1 Inhibitors

Journal of medicinal chemistry, 2007-08, Vol.50 (17), p.4162-4176

2007

Volltextzugriff (PDF)

Development of biotinylated and magnetic bead-immobilized enzymes for efficient glyco-engineering and isolation of antibodies

Bioorganic chemistry, 2021-07, Vol.112, p.104863-104863, Article 104863

2021

Volltextzugriff (PDF)

Discovery of 4′-(1,4-dihydro-indeno[1,2- c]pyrazol-3-yl)-benzonitriles and 4′-(1,4-dihydro-indeno[1,2- c]pyrazol-3-yl)-pyridine-2′-carbonitriles as potent checkpoint kinase 1 (Chk1) inhibitors

Bioorganic & medicinal chemistry letters, 2007-11, Vol.17 (21), p.5944-5951

2007

Volltextzugriff (PDF)

Correction: Development of glycosynthases with broad glycan specificity for the efficient glyco-remodeling of antibodies

Chemical communications (Cambridge, England), 2018-07, Vol.54 (56), p.7858-7858

2018

Volltextzugriff (PDF)

Synthesis and biological evaluation of 1-(2,4,5-trisubstituted phenyl)-3-(5-cyanopyrazin-2-yl)ureas as potent Chk1 kinase inhibitors

Bioorganic & medicinal chemistry letters, 2006-04, Vol.16 (8), p.2293-2298

2006

Volltextzugriff (PDF)

Synthesis and biological evaluation of 4′-(6,7-disubstituted-2,4-dihydro-indeno[1,2- c]pyrazol-3-yl)-biphenyl-4-ol as potent Chk1 inhibitors

Bioorganic & medicinal chemistry letters, 2007-08, Vol.17 (15), p.4308-4315

2007

Volltextzugriff (PDF)

Phenyl Glycolipids with Different Glycosyl Groups Exhibit Marked Differences in Murine and Human iNKT Cell Activation

ACS chemical biology, 2016-12, Vol.11 (12), p.3431-3441

2016

Volltextzugriff (PDF)

Synthesis and in-vitro biological activity of macrocyclic urea Chk1 inhibitors

Bioorganic & medicinal chemistry, 2007-12, Vol.17 (23), p.6499-6504

2007

Volltextzugriff (PDF)

Discovery of 3H-Benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective, and Orally Bioavailable Inhibitors of the Human Protooncogene Proviral Insertion Site in Moloney Murine Leukemia Virus (PIM) Kinases

Journal of medicinal chemistry, 2009-11, Vol.52 (21), p.6621-6636

2009

Volltextzugriff (PDF)

Isoxazolo[3,4- b]quinoline-3,4(1H,9H)-diones as unique, potent and selective inhibitors for Pim-1 and Pim-2 kinases: Chemistry, biological activities, and molecular modeling

Bioorganic & medicinal chemistry, 2008-10, Vol.18 (19), p.5206-5208

2008

Volltextzugriff (PDF)

Antitumor Activity of Orally Bioavailable Farnesyltransferase Inhibitor, ABT-100, Is Mediated by Antiproliferative, Proapoptotic, and Antiangiogenic Effects in Xenograft Models

Clinical cancer research, 2005-04, Vol.11 (8), p.3045-3054

2005

Volltextzugriff (PDF)

ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine]: I. A potent and selective cholinergic channel modulator with neuroprotective properties

The Journal of pharmacology and experimental therapeutics, 1997-10, Vol.283 (1), p.235

1997

Volltextzugriff (PDF)

ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine dihydrochloride]: II. A novel cholinergic channel modulator with effects on cognitive performance in rats and monkeys

The Journal of pharmacology and experimental therapeutics, 1997-10, Vol.283 (1), p.247

1997

Volltextzugriff (PDF)

Discovery of 1,4-dihydroindeno[1,2- c]pyrazoles as a novel class of potent and selective checkpoint kinase 1 inhibitors

Bioorganic & medicinal chemistry, 2007-04, Vol.15 (7), p.2759-2767

2007

Volltextzugriff (PDF)

Efficient Total Syntheses of Pumiliotoxins A and B. Applications of Iodide-Promoted Iminium Ion−Alkyne Cyclizations in Alkaloid Construction

Journal of the American Chemical Society, 1996-09, Vol.118 (38), p.9062-9072

1996

Volltextzugriff (PDF)

Synthesis and biological evaluation of 3-ethylidene-1,3-dihydro-indol-2-ones as novel checkpoint 1 inhibitors

Bioorganic & medicinal chemistry letters, 2006-01, Vol.16 (2), p.421-426

2006

Volltextzugriff (PDF)

Macrocyclic ureas as potent and selective Chk1 inhibitors: An improved synthesis, kinome profiling, structure–activity relationships, and preliminary pharmacokinetics

Bioorganic & medicinal chemistry, 2007-12, Vol.17 (23), p.6593-6601

2007

Volltextzugriff (PDF)

A facile synthesis of antitumoral indeno[1,2- c]pyrazole-4-one by mild oxidation with molecular oxygen

Tetrahedron letters, 2005-10, Vol.46 (44), p.7615-7618

2005

Volltextzugriff (PDF)

Menü

Weitere Dienste

Einstellungen

Development of glycosynthases with broad glycan specificity for the efficient glyco-remodeling of antibodies

An Effective Bacterial Fucosidase for Glycoprotein Remodeling

Selective Chk1 inhibitors differentially sensitize p53‐deficient cancer cells to cancer therapeutics

Chk1 inhibitors for novel cancer treatment

A common glycan structure on immunoglobulin G for enhancement of effector functions

Structure-Based Design, Synthesis, and Biological Evaluation of Potent and Selective Macrocyclic Checkpoint Kinase 1 Inhibitors

Unprecedented Role of Hybrid N-Glycans as Ligands for HIV‑1 Broadly Neutralizing Antibodies

Design, Synthesis, and Biological Activity of 5,10-Dihydro-dibenzo[b,e][1,4]diazepin-11-one-Based Potent and Selective Chk-1 Inhibitors

Development of biotinylated and magnetic bead-immobilized enzymes for efficient glyco-engineering and isolation of antibodies

Discovery of 4′-(1,4-dihydro-indeno[1,2- c]pyrazol-3-yl)-benzonitriles and 4′-(1,4-dihydro-indeno[1,2- c]pyrazol-3-yl)-pyridine-2′-carbonitriles as potent checkpoint kinase 1 (Chk1) inhibitors

Correction: Development of glycosynthases with broad glycan specificity for the efficient glyco-remodeling of antibodies

Synthesis and biological evaluation of 1-(2,4,5-trisubstituted phenyl)-3-(5-cyanopyrazin-2-yl)ureas as potent Chk1 kinase inhibitors

Synthesis and biological evaluation of 4′-(6,7-disubstituted-2,4-dihydro-indeno[1,2- c]pyrazol-3-yl)-biphenyl-4-ol as potent Chk1 inhibitors

Phenyl Glycolipids with Different Glycosyl Groups Exhibit Marked Differences in Murine and Human iNKT Cell Activation

Synthesis and in-vitro biological activity of macrocyclic urea Chk1 inhibitors

Discovery of 3H-Benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective, and Orally Bioavailable Inhibitors of the Human Protooncogene Proviral Insertion Site in Moloney Murine Leukemia Virus (PIM) Kinases

Isoxazolo[3,4- b]quinoline-3,4(1H,9H)-diones as unique, potent and selective inhibitors for Pim-1 and Pim-2 kinases: Chemistry, biological activities, and molecular modeling

Antitumor Activity of Orally Bioavailable Farnesyltransferase Inhibitor, ABT-100, Is Mediated by Antiproliferative, Proapoptotic, and Antiangiogenic Effects in Xenograft Models

ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine]: I. A potent and selective cholinergic channel modulator with neuroprotective properties

ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine dihydrochloride]: II. A novel cholinergic channel modulator with effects on cognitive performance in rats and monkeys

Discovery of 1,4-dihydroindeno[1,2- c]pyrazoles as a novel class of potent and selective checkpoint kinase 1 inhibitors

Efficient Total Syntheses of Pumiliotoxins A and B. Applications of Iodide-Promoted Iminium Ion−Alkyne Cyclizations in Alkaloid Construction

Synthesis and biological evaluation of 3-ethylidene-1,3-dihydro-indol-2-ones as novel checkpoint 1 inhibitors

Macrocyclic ureas as potent and selective Chk1 inhibitors: An improved synthesis, kinome profiling, structure–activity relationships, and preliminary pharmacokinetics

A facile synthesis of antitumoral indeno[1,2- c]pyrazole-4-one by mild oxidation with molecular oxygen

Suchergebnisse filtern