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Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of Resistance, and Implications for Drug Design

Annual review of biochemistry, 2018-06, Vol.87 (1), p.451-478

2018

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A COVID-19 mRNA vaccine encoding SARS-CoV-2 virus-like particles induces a strong antiviral-like immune response in mice

Cell research, 2020-10, Vol.30 (10), p.936-939

2020

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Crystal structure of an RNA-cleaving DNAzyme

Nature communications, 2017-12, Vol.8 (1), p.2006-10, Article 2006

2017

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DNA targeting by subtype I-D CRISPR–Cas shows type I and type III features

Nucleic acids research, 2020-10, Vol.48 (18), p.10470-10478

2020

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Prediction of lipid nanoparticles for mRNA vaccines by the machine learning algorithm

Acta pharmaceutica Sinica. B, 2022-06, Vol.12 (6), p.2950-2962

2022

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Structural basis for ribosome recycling by RRF and tRNA

Nature structural & molecular biology, 2020-01, Vol.27 (1), p.25-32

2020

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Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation

Cell, 2015-01, Vol.160 (1-2), p.219-227

2015

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A scalable system for the fast production of RNA with homogeneous terminal ends

RNA biology, 2022-12, Vol.19 (1), p.1077-1084

2022

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Structures of the mumps virus polymerase complex via cryo-electron microscopy

Nature communications, 2024-05, Vol.15 (1), p.4189-4189, Article 4189

2024

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Comprehensive structural characterization of the human AAA+ disaggregase CLPB in the apo- and substrate-bound states reveals a unique mode of action driven by oligomerization

PLoS biology, 2023-02, Vol.21 (2), p.e3001987-e3001987

2023

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Identification of cross-linked peptides from complex samples

Nature methods, 2012-09, Vol.9 (9), p.904-906

2012

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Modeling on in vivo disposition and cellular transportation of RNA lipid nanoparticles via quantum mechanics/physiologically-based pharmacokinetic approaches

Acta pharmaceutica Sinica. B, 2024-10, Vol.14 (10), p.4591-4607

2024

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An RNA-binding complex involved in ribosome biogenesis contains a protein with homology to tRNA CCA-adding enzyme

PLoS biology, 2013-10, Vol.11 (10), p.e1001669

2013

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Stability and Bifurcation of Tumor Immune Model with Time Delay

BIO web of conferences, 2023-01, Vol.59, p.2017

2023

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Box C/D guide RNAs recognize a maximum of 10 nt of substrates

Proceedings of the National Academy of Sciences - PNAS, 2016-09, Vol.113 (39), p.10878-10883

2016

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A Single Dose of Anti-HBsAg Antibody-Encoding mRNA-LNPs Suppressed HBsAg Expression: a Potential Cure of Chronic Hepatitis B Virus Infection

mBio, 2022-07, Vol.13 (4), p.e0161222-e0161222

2022

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An mRNA-based T-cell-inducing antigen strengthens COVID-19 vaccine against SARS-CoV-2 variants

Nature communications, 2023-05, Vol.14 (1), p.2962-2962, Article 2962

2023

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Structural basis for inhibition of an archaeal CRISPR–Cas type I-D large subunit by an anti-CRISPR protein

Nature communications, 2020-11, Vol.11 (1), p.5993-5993, Article 5993

2020

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Crystal Structure of Human mitoNEET Reveals Distinct Groups of Iron-Sulfur Proteins

Proceedings of the National Academy of Sciences - PNAS, 2007-09, Vol.104 (37), p.14640-14645

2007

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SIRT2‐knockdown rescues GARS‐induced Charcot‐Marie‐Tooth neuropathy

Aging cell, 2021-06, Vol.20 (6), p.e13391-n/a

2021

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Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond

Nucleic acids research, 2020-05, Vol.48 (9), p.4946-4959

2020

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Structural basis for site-specific ribose methylation by box C/D RNA protein complexes

Nature (London), 2011-01, Vol.469 (7331), p.559-563

2011

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Structure and molecular evolution of CDGSH iron-sulfur domains

PloS one, 2011-09, Vol.6 (9), p.e24790-e24790

2011

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Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome

Science (American Association for the Advancement of Science), 2014-08, Vol.345 (6197), p.684-687

2014

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Crystal structures and insights into precursor tRNA 5’-end processing by prokaryotic minimal protein-only RNase P

Nature communications, 2022-04, Vol.13 (1), p.2290-2290, Article 2290

2022

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Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of Resistance, and Implications for Drug Design

A COVID-19 mRNA vaccine encoding SARS-CoV-2 virus-like particles induces a strong antiviral-like immune response in mice

Crystal structure of an RNA-cleaving DNAzyme

DNA targeting by subtype I-D CRISPR–Cas shows type I and type III features

Prediction of lipid nanoparticles for mRNA vaccines by the machine learning algorithm

Structural basis for ribosome recycling by RRF and tRNA

Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation

A scalable system for the fast production of RNA with homogeneous terminal ends

Structures of the mumps virus polymerase complex via cryo-electron microscopy

Comprehensive structural characterization of the human AAA+ disaggregase CLPB in the apo- and substrate-bound states reveals a unique mode of action driven by oligomerization

Identification of cross-linked peptides from complex samples

Modeling on in vivo disposition and cellular transportation of RNA lipid nanoparticles via quantum mechanics/physiologically-based pharmacokinetic approaches

An RNA-binding complex involved in ribosome biogenesis contains a protein with homology to tRNA CCA-adding enzyme

Stability and Bifurcation of Tumor Immune Model with Time Delay

Box C/D guide RNAs recognize a maximum of 10 nt of substrates

A Single Dose of Anti-HBsAg Antibody-Encoding mRNA-LNPs Suppressed HBsAg Expression: a Potential Cure of Chronic Hepatitis B Virus Infection

An mRNA-based T-cell-inducing antigen strengthens COVID-19 vaccine against SARS-CoV-2 variants

Structural basis for inhibition of an archaeal CRISPR–Cas type I-D large subunit by an anti-CRISPR protein

Crystal Structure of Human mitoNEET Reveals Distinct Groups of Iron-Sulfur Proteins

SIRT2‐knockdown rescues GARS‐induced Charcot‐Marie‐Tooth neuropathy

Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond

Structural basis for site-specific ribose methylation by box C/D RNA protein complexes

Structure and molecular evolution of CDGSH iron-sulfur domains

Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome

Crystal structures and insights into precursor tRNA 5’-end processing by prokaryotic minimal protein-only RNase P

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