UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Single-Stranded RNAs Use RNAi to Potently and Allele-Selectively Inhibit Mutant Huntingtin Expression

Cell, 2012-08, Vol.150 (5), p.895-908

2012

Volltextzugriff (PDF)

Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice

Nucleic acids research, 2014-07, Vol.42 (13), p.8796-8807

2014

Volltextzugriff (PDF)

Single-Stranded siRNAs Activate RNAi in Animals

Cell, 2012-08, Vol.150 (5), p.883-894

2012

Volltextzugriff (PDF)

Structural Analysis of Human Argonaute‑2 Bound to a Modified siRNA Guide

Journal of the American Chemical Society, 2016-07, Vol.138 (28), p.8694-8697

2016

Volltextzugriff (PDF)

RNA cleavage products generated by antisense oligonucleotides and siRNAs are processed by the RNA surveillance machinery

Nucleic acids research, 2016-04, Vol.44 (7), p.3351-3363

2016

Volltextzugriff (PDF)

Synthesis, biophysical properties and biological activity of second generation antisense oligonucleotides containing chiral phosphorothioate linkages

Nucleic acids research, 2014-12, Vol.42 (22), p.13456-13468

2014

Volltextzugriff (PDF)

Defining the factors that contribute to on-target specificity of antisense oligonucleotides

PloS one, 2014-07, Vol.9 (7), p.e101752-e101752

2014

Volltextzugriff (PDF)

Human RNase H1 is associated with protein P32 and is involved in mitochondrial pre-rRNA processing

PloS one, 2013-08, Vol.8 (8), p.e71006-e71006

2013

Volltextzugriff (PDF)

Synergistic effect of phosphorothioate, 5′-vinylphosphonate and GalNAc modifications for enhancing activity of synthetic siRNA

Bioorganic & medicinal chemistry letters, 2016-06, Vol.26 (12), p.2817-2820

2016

Volltextzugriff (PDF)

Determination of the Role of the Human RNase H1 in the Pharmacology of DNA-like Antisense Drugs

The Journal of biological chemistry, 2004-04, Vol.279 (17), p.17181-17189

2004

Volltextzugriff (PDF)

Binding and Cleavage Specificities of Human Argonaute2

The Journal of biological chemistry, 2009-09, Vol.284 (38), p.26017-26028

2009

Volltextzugriff (PDF)

ss-siRNAs allele selectively inhibit ataxin-3 expression: multiple mechanisms for an alternative gene silencing strategy

Nucleic acids research, 2013-11, Vol.41 (20), p.9570-9583

2013

Volltextzugriff (PDF)

Allele-Selective Inhibition of Mutant Atrophin‑1 Expression by Duplex and Single-Stranded RNAs

Biochemistry (Easton), 2014-07, Vol.53 (28), p.4510-4518

2014

Volltextzugriff (PDF)

Lipid Nanoparticles Improve Activity of Single-Stranded siRNA and Gapmer Antisense Oligonucleotides in Animals

ACS chemical biology, 2013-07, Vol.8 (7), p.1402-1406

2013

Volltextzugriff (PDF)

Human RNase H1 Discriminates between Subtle Variations in the Structure of the Heteroduplex Substrate

Molecular pharmacology, 2007-01, Vol.71 (1), p.83-91

2007

Volltextzugriff (PDF)

Viable RNaseH1 knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver function

Nucleic acids research, 2016-06, Vol.44 (11), p.5299-5312

2016

Volltextzugriff (PDF)

Human Dicer Binds Short Single-strand and Double-strand RNA with High Affinity and Interacts with Different Regions of the Nucleic Acids

The Journal of biological chemistry, 2009-01, Vol.284 (4), p.2535-2548

2009

Volltextzugriff (PDF)

Identification of metabolically stable 5'-phosphate analogs that support single-stranded siRNA activity

Nucleic acids research, 2015-03, Vol.43 (6), p.2993-3011

2015

Volltextzugriff (PDF)

Structural Requirements at the Catalytic Site of the Heteroduplex Substrate for Human RNase H1 Catalysis

The Journal of biological chemistry, 2004-08, Vol.279 (35), p.36317-36326

2004

Volltextzugriff (PDF)

The Positional Influence of the Helical Geometry of the Heteroduplex Substrate on Human RNase H1 Catalysis

Molecular pharmacology, 2007-01, Vol.71 (1), p.73-82

2007

Volltextzugriff (PDF)

Reduced levels of Ago2 expression result in increased siRNA competition in mammalian cells

Nucleic acids research, 2007-10, Vol.35 (19), p.6598-6610

2007

Volltextzugriff (PDF)

Identification of metabolically stable 5΄-phosphate analogs that support single-stranded siRNA activity

Nucleic acids research, 2017-06, Vol.45 (11), p.6994-6994

2017

Volltextzugriff (PDF)

Human RNase H1 Uses One Tryptophan and Two Lysines to Position the Enzyme at the 3′-DNA/5′-RNA Terminus of the Heteroduplex Substrate

The Journal of biological chemistry, 2003-12, Vol.278 (50), p.49860-49867

2003

Volltextzugriff (PDF)

Co-Administration of an Excipient Oligonucleotide Helps Delineate Pathways of Productive and Nonproductive Uptake of Phosphorothioate Antisense Oligonucleotides in the Liver

Nucleic acid therapeutics, 2017-08, Vol.27 (4), p.209-220

2017

Volltextzugriff (PDF)

Binding Affinity and Specificity of Escherichia coli RNase H1: Impact on the Kinetics of Catalysis of Antisense Oligonucleotide−RNA Hybrids

Biochemistry (Easton), 1997-01, Vol.36 (2), p.390-398

1997

Volltextzugriff (PDF)

1 – 25 von 58

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(57)
Mit Volltextzugriff
(45)

Publikationsform

Artikel
(58)

Sprache

Englisch
(58)
Japanisch
(24)

Erscheinungsjahr

n.n

Thema

Science & Technology
(45)
Life Sciences & Biomedicine
(42)
Biochemistry & Molecular Biology
(39)
Humans
(31)
Animals
(16)
Base Sequence
(15)
Kinetics
(15)
Ribonuclease H - Metabolism
(15)
Molecular Sequence Data
(13)
Hela Cells
(12)
Mice
(12)
Oligonucleotides, Antisense - Chemistry
(11)
Rna Interference
(10)
Rna, Small Interfering - Metabolism
(10)
Rna, Messenger - Metabolism
(9)
Substrate Specificity
(9)
Oligonucleotides, Antisense - Metabolism
(8)
Rna
(8)
Amino Acid Sequence
(7)
Cell Line
(7)

15 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Single-Stranded RNAs Use RNAi to Potently and Allele-Selectively Inhibit Mutant Huntingtin Expression

Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice

Single-Stranded siRNAs Activate RNAi in Animals

Structural Analysis of Human Argonaute‑2 Bound to a Modified siRNA Guide

RNA cleavage products generated by antisense oligonucleotides and siRNAs are processed by the RNA surveillance machinery

Synthesis, biophysical properties and biological activity of second generation antisense oligonucleotides containing chiral phosphorothioate linkages

Defining the factors that contribute to on-target specificity of antisense oligonucleotides

Human RNase H1 is associated with protein P32 and is involved in mitochondrial pre-rRNA processing

Synergistic effect of phosphorothioate, 5′-vinylphosphonate and GalNAc modifications for enhancing activity of synthetic siRNA

Determination of the Role of the Human RNase H1 in the Pharmacology of DNA-like Antisense Drugs

Binding and Cleavage Specificities of Human Argonaute2

ss-siRNAs allele selectively inhibit ataxin-3 expression: multiple mechanisms for an alternative gene silencing strategy

Allele-Selective Inhibition of Mutant Atrophin‑1 Expression by Duplex and Single-Stranded RNAs

Lipid Nanoparticles Improve Activity of Single-Stranded siRNA and Gapmer Antisense Oligonucleotides in Animals

Human RNase H1 Discriminates between Subtle Variations in the Structure of the Heteroduplex Substrate

Viable RNaseH1 knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver function

Human Dicer Binds Short Single-strand and Double-strand RNA with High Affinity and Interacts with Different Regions of the Nucleic Acids

Identification of metabolically stable 5'-phosphate analogs that support single-stranded siRNA activity

Structural Requirements at the Catalytic Site of the Heteroduplex Substrate for Human RNase H1 Catalysis

The Positional Influence of the Helical Geometry of the Heteroduplex Substrate on Human RNase H1 Catalysis

Reduced levels of Ago2 expression result in increased siRNA competition in mammalian cells

Identification of metabolically stable 5΄-phosphate analogs that support single-stranded siRNA activity

Human RNase H1 Uses One Tryptophan and Two Lysines to Position the Enzyme at the 3′-DNA/5′-RNA Terminus of the Heteroduplex Substrate

Co-Administration of an Excipient Oligonucleotide Helps Delineate Pathways of Productive and Nonproductive Uptake of Phosphorothioate Antisense Oligonucleotides in the Liver

Binding Affinity and Specificity of Escherichia coli RNase H1: Impact on the Kinetics of Catalysis of Antisense Oligonucleotide−RNA Hybrids

Suchergebnisse filtern