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Transcriptome profiling reveals distinct alterations in the B-cell signature and dysregulation of peripheral B-cell subsets in sickle cell anemia patients

Experimental hematology, 2024-09, Vol.137, p.104254, Article 104254

2024

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Suppression of multiple anti‐apoptotic BCL2 family proteins recapitulates the effects of JAK2 inhibitors in JAK2V617F driven myeloproliferative neoplasms

Cancer science, 2022-02, Vol.113 (2), p.597-608

2022

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AD80, a multikinase inhibitor, exhibits antineoplastic effects in acute leukemia cellular models targeting the PI3K/STMN1 axis

Investigational new drugs, 2021-08, Vol.39 (4), p.1139-1149

2021

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NT157 exerts antineoplastic activity by targeting JNK and AXL signaling in lung cancer cells

Scientific reports, 2022-10, Vol.12 (1), p.17092-17092, Article 17092

2022

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Comprehensive analysis of cytoskeleton regulatory genes identifies ezrin as a prognostic marker and molecular target in acute myeloid leukemia

Cellular oncology (Dordrecht), 2021-10, Vol.44 (5), p.1105-1117

2021

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Pharmacological Inhibition of PIP4K2 Potentiates Venetoclax-Induced Apoptosis in Acute Myeloid Leukemia

International journal of molecular sciences, 2023-12, Vol.24 (23), p.16899

2023

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2-Methoxyestradiol-3,17- O , O -bis-sulfamate (STX140) Inhibits Proliferation and Invasion via Senescence Pathway Induction in Human BRAFi-Resistant Melanoma Cells

International journal of molecular sciences, 2023-07, Vol.24 (14), p.11314

2023

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STMN1 is highly expressed and contributes to clonogenicity in acute promyelocytic leukemia cells

Investigational new drugs, 2022-04, Vol.40 (2), p.438-452

2022

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The PIP4K2 inhibitor THZ-P1-2 exhibits antileukemia activity by disruption of mitochondrial homeostasis and autophagy

Blood cancer journal (New York), 2022-11, Vol.12 (11), p.151-151, Article 151

2022

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Comprehensive analysis of the HCK gene in myeloid neoplasms: Insights into biological functions, prognosis, and response to antineoplastic agents

Hematology, Transfusion and Cell Therapy, 2024-07, Vol.46 (3), p.273-282

2024

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Stathmin 1 is highly expressed and associated with survival outcome in malignant adrenocortical tumours

Investigational new drugs, 2020-06, Vol.38 (3), p.899-908

2020

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Exploring redox vulnerabilities in JAK2V617F-positive cellular models

Hematology, Transfusion and Cell Therapy, 2021-10, Vol.43 (4), p.430-436

2021

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ARHGAP6 transcript levels are associated with molecular risk and impact survival outcomes in acute myeloid leukemia

Hematology, Transfusion and Cell Therapy, 2024-01, Vol.46 (1), p.101-105

2024

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P347: PHARMACOLOGICAL EZRIN INHIBITION REDUCES GROWTH, ADHESION, MIGRATION AND REGULATE GENE RELATED TO APOPTOSIS AND CELL CYCLE IN ACUTE LYMPHOBLASTIC LEUKAEMIA

HemaSphere, 2023-08, Vol.7 (S3), p.e65047ca-n/a

2023

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PB1826: CELLULAR AND MOLECULAR CHARACTERIZATION OF THE ANTINEOPLASTIC EFFECTS OF CEPHALOCHROMIN IN MODELS OF ACUTE MYELOID LEUKEMIA

HemaSphere, 2023-08, Vol.7 (S3), p.e35451e1-n/a

2023

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Obatoclax reduces cell viability of acute myeloid leukemia cell lines independently of their sensitivity to venetoclax

Hematology, Transfusion and Cell Therapy, 2022-01, Vol.44 (1), p.124-127

2022

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Effect of FKBP12-Derived Intracellular Peptides on Rapamycin-Induced FKBP-FRB Interaction and Autophagy

Cells (Basel, Switzerland), 2022-01, Vol.11 (3), p.385

2022

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NT157 as an Anticancer Drug Candidate That Targets Kinase- and Phosphatase-Mediated Signaling

Kinases and Phosphatases, 2024-05, Vol.2 (2), p.179-189

2024

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The Ginkgo biloba extract, EGb 761, fails to reduce brain infarct size in rats after transient, middle cerebral artery occlusion in conditions of unprevented, ischemia-induced fever

Phytotherapy research, 2006-06, Vol.20 (6), p.438-443

2006

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Identification of Vulnerabilities for Pharmacological Inhibition of PIP4K2s in Acute Myeloid Leukemia

Blood, 2023-11, Vol.142 (Supplement 1), p.5774-5774

2023

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Cephalochromin-Induced Mitochondrial Damage Overcomes Venetoclax-Resistance in Acute Myeloid Leukemia Models

Blood, 2023-11, Vol.142 (Supplement 1), p.5751-5751

2023

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A novel version of the 8-arm radial maze: effects of cerebral ischemia on learning and memory

Journal of neuroscience methods, 2004-01, Vol.132 (1), p.9-18

2004

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NSC305787, a pharmacological ezrin inhibitor, exhibits antineoplastic activity in pancreatic cancer cells

Investigational new drugs, 2022-08, Vol.40 (4), p.728-737

2022

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Transcriptome profiling reveals distinct alterations in the B-cell signature and dysregulation of peripheral B-cell subsets in sickle cell anemia patients

Suppression of multiple anti‐apoptotic BCL2 family proteins recapitulates the effects of JAK2 inhibitors in JAK2V617F driven myeloproliferative neoplasms

AD80, a multikinase inhibitor, exhibits antineoplastic effects in acute leukemia cellular models targeting the PI3K/STMN1 axis

NT157 exerts antineoplastic activity by targeting JNK and AXL signaling in lung cancer cells

Comprehensive analysis of cytoskeleton regulatory genes identifies ezrin as a prognostic marker and molecular target in acute myeloid leukemia

Pharmacological Inhibition of PIP4K2 Potentiates Venetoclax-Induced Apoptosis in Acute Myeloid Leukemia

2-Methoxyestradiol-3,17- O , O -bis-sulfamate (STX140) Inhibits Proliferation and Invasion via Senescence Pathway Induction in Human BRAFi-Resistant Melanoma Cells

STMN1 is highly expressed and contributes to clonogenicity in acute promyelocytic leukemia cells

The PIP4K2 inhibitor THZ-P1-2 exhibits antileukemia activity by disruption of mitochondrial homeostasis and autophagy

Comprehensive analysis of the HCK gene in myeloid neoplasms: Insights into biological functions, prognosis, and response to antineoplastic agents

Stathmin 1 is highly expressed and associated with survival outcome in malignant adrenocortical tumours

Exploring redox vulnerabilities in JAK2V617F-positive cellular models

ARHGAP6 transcript levels are associated with molecular risk and impact survival outcomes in acute myeloid leukemia

P347: PHARMACOLOGICAL EZRIN INHIBITION REDUCES GROWTH, ADHESION, MIGRATION AND REGULATE GENE RELATED TO APOPTOSIS AND CELL CYCLE IN ACUTE LYMPHOBLASTIC LEUKAEMIA

PB1826: CELLULAR AND MOLECULAR CHARACTERIZATION OF THE ANTINEOPLASTIC EFFECTS OF CEPHALOCHROMIN IN MODELS OF ACUTE MYELOID LEUKEMIA

Obatoclax reduces cell viability of acute myeloid leukemia cell lines independently of their sensitivity to venetoclax

Effect of FKBP12-Derived Intracellular Peptides on Rapamycin-Induced FKBP-FRB Interaction and Autophagy

Long-Term Effects of Allogeneic Hematopoietic Stem Cell Transplantation on Systemic Inflammation in Sickle Cell Disease Patients

NT157 as an Anticancer Drug Candidate That Targets Kinase- and Phosphatase-Mediated Signaling

Allogeneic haematopoietic stem cell transplantation resets T‐ and B‐cell compartments in sickle cell disease patients

The Ginkgo biloba extract, EGb 761, fails to reduce brain infarct size in rats after transient, middle cerebral artery occlusion in conditions of unprevented, ischemia-induced fever

Identification of Vulnerabilities for Pharmacological Inhibition of PIP4K2s in Acute Myeloid Leukemia

Cephalochromin-Induced Mitochondrial Damage Overcomes Venetoclax-Resistance in Acute Myeloid Leukemia Models

A novel version of the 8-arm radial maze: effects of cerebral ischemia on learning and memory

NSC305787, a pharmacological ezrin inhibitor, exhibits antineoplastic activity in pancreatic cancer cells

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