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Protease-activated receptor 2 attenuates doxorubicin-induced apoptosis in colon cancer cells

Journal of cell communication and signaling, 2023-12, Vol.17 (4), p.1293-1307

2023

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C5aR and C3aR antagonists each inhibit diet‐induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling

The FASEB journal, 2013-02, Vol.27 (2), p.822-831

2013

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Inflammatory responses induced by lipopolysaccharide are amplified in primary human monocytes but suppressed in macrophages by complement protein C5a

The Journal of immunology (1950), 2013-10, Vol.191 (8), p.4308-4316

2013

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Ras-Related Protein Rab5a Regulates Complement C5a Receptor Trafficking, Chemotaxis, and Chemokine Secretion in Human Macrophages

Journal of innate immunity, 2023-01, Vol.15 (1), p.468-484

2023

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Antifibrotic activity of an inhibitor of histone deacetylases in DOCA‐salt hypertensive rats

British journal of pharmacology, 2010-04, Vol.159 (7), p.1408-1417

2010

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Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a

Nature communications, 2017-08, Vol.8 (1), p.351-15, Article 351

2017

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Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibition

Communications biology, 2020-12, Vol.3 (1), p.782-782, Article 782

2020

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Temporal perturbation of histone deacetylase activity reveals a requirement for HDAC1–3 in mesendoderm cell differentiation

Cell reports (Cambridge), 2022-05, Vol.39 (7), p.110818-110818, Article 110818

2022

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An Inhibitor of Phospholipase A2 Group IIA Modulates Adipocyte Signaling and Protects Against Diet-Induced Metabolic Syndrome in Rats

Diabetes (New York, N.Y.), 2012-09, Vol.61 (9), p.2320-2329

2012

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Landscaping macrocyclic peptides: stapling hDM2-binding peptides for helicity, protein affinity, proteolytic stability and cell uptake

RSC chemical biology, 2022-07, Vol.3 (7), p.895-94

2022

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Protease-activated receptor 2: a promising therapeutic target for women's cancers

The Journal of pharmacology and experimental therapeutics, 2024-05, p.JPET-MR-2024-002176

2024

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A study on bone cement containing magnesium potassium phosphate for bone repair

Cogent biology, 2018-01, Vol.4 (1), p.1487255

2018

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Using pgRNA-Cas9 system to knockout MKL1 inhibited cell migration and proliferation

Cogent biology, 2018-01, Vol.4 (1), p.1426255

2018

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Analysis of serum electrolyte and lipid profile in young Bangladeshi female with Type II Diabetes

Cogent biology, 2018-01, Vol.4 (1), p.1431474

2018

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Structure−Activity Relationships for Substrate-Based Inhibitors of Human Complement Factor B

Journal of medicinal chemistry, 2009-10, Vol.52 (19), p.6042-6052

2009

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Helical structure in cyclic peptides: effect of -methyl amides esters

Chemical communications (Cambridge, England), 2022-11, Vol.58 (89), p.12475-12478

2022

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Tuning Electrostatic and Hydrophobic Surfaces of Aromatic Rings to Enhance Membrane Association and Cell Uptake of Peptides

Angewandte Chemie International Edition, 2022-07, Vol.61 (29), p.e202203995-n/a

International ed. in English, 2022

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PAR2 induces ovarian cancer cell motility by merging three signalling pathways to transactivate EGFR

British journal of pharmacology, 2021-02, Vol.178 (4), p.913-932

2021

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A Potent Antagonist of Protease-Activated Receptor 2 That Inhibits Multiple Signaling Functions in Human Cancer Cells

The Journal of pharmacology and experimental therapeutics, 2018-02, Vol.364 (2), p.246-257

2018

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Bicyclic Helical Peptides as Dual Inhibitors Selective for Bcl2A1 and Mcl‑1 Proteins

Journal of medicinal chemistry, 2018-04, Vol.61 (7), p.2962-2972

2018

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Stereoelectronic Effects Dictate Molecular Conformation and Biological Function of Heterocyclic Amides

Journal of the American Chemical Society, 2014-08, Vol.136 (34), p.11914-11917

2014

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Diet‐induced obesity, adipose inflammation, and metabolic dysfunction correlating with PAR2 expression are attenuated by PAR2 antagonism

The FASEB journal, 2013-12, Vol.27 (12), p.4757-4767

2013

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Achiral Derivatives of Hydroxamate AR-42 Potently Inhibit Class I HDAC Enzymes and Cancer Cell Proliferation

Journal of medicinal chemistry, 2020-06, Vol.63 (11), p.5956-5971

2020

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Helical structure in cyclic peptides: effect of N -methyl amides versus esters

Chemical communications (Cambridge, England), 2022-11, Vol.58 (89), p.12475-12478

2022

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A novel inhibitor of class IIa histone deacetylases attenuates collagen‐induced arthritis

British journal of pharmacology, 2024-12, Vol.181 (23), p.4804-4821

2024

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Protease-activated receptor 2 attenuates doxorubicin-induced apoptosis in colon cancer cells

C5aR and C3aR antagonists each inhibit diet‐induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling

Inflammatory responses induced by lipopolysaccharide are amplified in primary human monocytes but suppressed in macrophages by complement protein C5a

Ras-Related Protein Rab5a Regulates Complement C5a Receptor Trafficking, Chemotaxis, and Chemokine Secretion in Human Macrophages

Antifibrotic activity of an inhibitor of histone deacetylases in DOCA‐salt hypertensive rats

Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a

Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibition

Temporal perturbation of histone deacetylase activity reveals a requirement for HDAC1–3 in mesendoderm cell differentiation

An Inhibitor of Phospholipase A2 Group IIA Modulates Adipocyte Signaling and Protects Against Diet-Induced Metabolic Syndrome in Rats

Landscaping macrocyclic peptides: stapling hDM2-binding peptides for helicity, protein affinity, proteolytic stability and cell uptake

Protease-activated receptor 2: a promising therapeutic target for women's cancers

A study on bone cement containing magnesium potassium phosphate for bone repair

Using pgRNA-Cas9 system to knockout MKL1 inhibited cell migration and proliferation

Analysis of serum electrolyte and lipid profile in young Bangladeshi female with Type II Diabetes

Structure−Activity Relationships for Substrate-Based Inhibitors of Human Complement Factor B

Helical structure in cyclic peptides: effect of -methyl amides esters

Tuning Electrostatic and Hydrophobic Surfaces of Aromatic Rings to Enhance Membrane Association and Cell Uptake of Peptides

PAR2 induces ovarian cancer cell motility by merging three signalling pathways to transactivate EGFR

A Potent Antagonist of Protease-Activated Receptor 2 That Inhibits Multiple Signaling Functions in Human Cancer Cells

Bicyclic Helical Peptides as Dual Inhibitors Selective for Bcl2A1 and Mcl‑1 Proteins

Stereoelectronic Effects Dictate Molecular Conformation and Biological Function of Heterocyclic Amides

Diet‐induced obesity, adipose inflammation, and metabolic dysfunction correlating with PAR2 expression are attenuated by PAR2 antagonism

Achiral Derivatives of Hydroxamate AR-42 Potently Inhibit Class I HDAC Enzymes and Cancer Cell Proliferation

Helical structure in cyclic peptides: effect of N -methyl amides versus esters

A novel inhibitor of class IIa histone deacetylases attenuates collagen‐induced arthritis

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