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Randomised clinical trial: safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple oral doses of tegoprazan (CJ‐12420), a novel potassium‐competitive acid blocker, in healthy male subjects

Alimentary pharmacology & therapeutics, 2019-10, Vol.50 (7), p.751-759

2019

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Pharmacokinetic and Pharmacodynamic Modeling Analysis of Delpazolid (LCB01‐0371) in Adult Patients with Pulmonary Tuberculosis

Journal of clinical pharmacology, 2024-07, Vol.64 (7), p.849-859

2024

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Pharmacologic properties of high-dose ambroxol in four patients with Gaucher disease and myoclonic epilepsy

Journal of medical genetics, 2020-02, Vol.57 (2), p.124-131

2020

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Exposure-response analysis using time-to-event data for bevacizumab biosimilar SB8 and the reference bevacizumab

Frontiers in pharmacology, 2024-01, Vol.14, p.1288308

2024

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Modeling Approach with Therapeutic Drug Monitoring Data to Describe Time Course of Clozapine Exposure and Positive and Negative Syndrome Scale Scores

Therapeutic drug monitoring, 2023-06, Vol.45 (3), p.417-424

2023

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Quantitative Predictive Models for the Degree of Disability After Acute Ischemic Stroke

Journal of clinical pharmacology, 2018-04, Vol.58 (4), p.549-557

2018

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Pharmacokinetic and Pharmacodynamic Evaluation of Intravenous Levetiracetam in Children With Epilepsy

Journal of clinical pharmacology, 2018-12, Vol.58 (12), p.1586-1596

2018

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Many-to-Many Disjoint Path Covers in the Presence of Faulty Elements

IEEE transactions on computers, 2009-04, Vol.58 (4), p.528-540

2009

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Clinical Implications of CYP2D6 Genotypes Predictive of Tamoxifen Pharmacokinetics in Metastatic Breast Cancer

Journal of clinical oncology, 2007-09, Vol.25 (25), p.3837-3845

2007

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Dynamic contrast-enhanced MRI for oncology drug development

Journal of magnetic resonance imaging, 2016-08, Vol.44 (2), p.251-264

2016

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Quantitative Modeling Analysis Demonstrates the Impact of CYP2C19 and CYP2D6 Genetic Polymorphisms on the Pharmacokinetics of Amitriptyline and Its Metabolite, Nortriptyline

Journal of clinical pharmacology, 2019-04, Vol.59 (4), p.532-540

2019

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Modeling and simulation to predict the degree of disability over time in acute ischemic stroke patients

Clinical and translational science, 2021-09, Vol.14 (5), p.1988-1996

2021

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Disease Progression Modeling Analysis of the Change of Bone Mineral Density by Postoperative Hormone Therapies in Postmenopausal Patients With Early Breast Cancer

Journal of clinical pharmacology, 2019-11, Vol.59 (11), p.1543-1550

2019

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Comparison of Pharmacodynamics between Tegoprazan and Dexlansoprazole Regarding Nocturnal Acid Breakthrough: A Randomized Crossover Study

Gut and Liver, 2023, 17(1), , pp.92-99

2023

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Effect of Low-Dose Versus Standard-Dose Ticagrelor and Clopidogrel on Platelet Inhibition in Acute Coronary Syndromes

Journal of the American College of Cardiology, 2018-04, Vol.71 (14), p.1594-1595

2018

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PK Modeling of L-4-Boronophenylalanine and Development of Bayesian Predictive Platform for L-4-Boronophenylalanine PKs for Boron Neutron Capture Therapy

Pharmaceuticals (Basel, Switzerland), 2024-02, Vol.17 (3), p.301

2024

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A phase 1 dose-escalation and dose-expansion study to assess the safety and efficacy of CKD-516, a novel vascular disrupting agent, in combination with Irinotecan in patients with previously treated metastatic colorectal cancer

Investigational new drugs, 2021-10, Vol.39 (5), p.1335-1347

2021

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Pharmacokinetics of Hydroxychloroquine and Its Clinical Implications in Chemoprophylaxis against Malaria Caused by Plasmodium vivax

Antimicrobial Agents and Chemotherapy, 2009-04, Vol.53 (4), p.1468-1475

2009

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Comprehensive Analysis of UGT1A Polymorphisms Predictive for Pharmacokinetics and Treatment Outcome in Patients With Non–Small-Cell Lung Cancer Treated With Irinotecan and Cisplatin

Journal of clinical oncology, 2006-05, Vol.24 (15), p.2237-2244

2006

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Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan‐pharmacokinetics and clinical outcome in patients with advanced non‐small cell lung cancer

Cancer, 2007-07, Vol.110 (1), p.138-147

2007

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Pharmacokinetic equivalence of CT‐P17 to high‐concentration (100 mg/ml) reference adalimumab: A randomized phase I study in healthy subjects

Clinical and translational science, 2021-07, Vol.14 (4), p.1280-1291

2021

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A Phase I/IIa Study of DHP107, a Novel Oral Paclitaxel Formulation, in Patients with Advanced Solid Tumors or Gastric Cancer

The oncologist (Dayton, Ohio), 2017-02, Vol.22 (2), p.129-e8

2017

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Impact of CYP2D6, CYP3A5, CYP2C19, CYP2A6, SLCO1B1, ABCB1, and ABCG2 gene polymorphisms on the pharmacokinetics of simvastatin and simvastatin acid

Pharmacogenetics and genomics, 2015-12, Vol.25 (12), p.595-608

2015

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Pharmacokinetic and Pharmacodynamic Modeling and Simulation Analysis of Prasugrel in Healthy Male Volunteers

Clinical pharmacology in drug development, 2023-01, Vol.12 (1), p.21-29

2023

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Effects of Renal Impairment on the Pharmacokinetics and Safety of Udenafil

Journal of clinical pharmacology, 2018-07, Vol.58 (7), p.905-912

2018

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Randomised clinical trial: safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple oral doses of tegoprazan (CJ‐12420), a novel potassium‐competitive acid blocker, in healthy male subjects

Pharmacokinetic and Pharmacodynamic Modeling Analysis of Delpazolid (LCB01‐0371) in Adult Patients with Pulmonary Tuberculosis

Pharmacologic properties of high-dose ambroxol in four patients with Gaucher disease and myoclonic epilepsy

Exposure-response analysis using time-to-event data for bevacizumab biosimilar SB8 and the reference bevacizumab

Modeling Approach with Therapeutic Drug Monitoring Data to Describe Time Course of Clozapine Exposure and Positive and Negative Syndrome Scale Scores

Quantitative Predictive Models for the Degree of Disability After Acute Ischemic Stroke

Pharmacokinetic and Pharmacodynamic Evaluation of Intravenous Levetiracetam in Children With Epilepsy

Many-to-Many Disjoint Path Covers in the Presence of Faulty Elements

Clinical Implications of CYP2D6 Genotypes Predictive of Tamoxifen Pharmacokinetics in Metastatic Breast Cancer

Dynamic contrast-enhanced MRI for oncology drug development

Quantitative Modeling Analysis Demonstrates the Impact of CYP2C19 and CYP2D6 Genetic Polymorphisms on the Pharmacokinetics of Amitriptyline and Its Metabolite, Nortriptyline

Modeling and simulation to predict the degree of disability over time in acute ischemic stroke patients

Disease Progression Modeling Analysis of the Change of Bone Mineral Density by Postoperative Hormone Therapies in Postmenopausal Patients With Early Breast Cancer

Comparison of Pharmacodynamics between Tegoprazan and Dexlansoprazole Regarding Nocturnal Acid Breakthrough: A Randomized Crossover Study

Effect of Low-Dose Versus Standard-Dose Ticagrelor and Clopidogrel on Platelet Inhibition in Acute Coronary Syndromes

PK Modeling of L-4-Boronophenylalanine and Development of Bayesian Predictive Platform for L-4-Boronophenylalanine PKs for Boron Neutron Capture Therapy

A phase 1 dose-escalation and dose-expansion study to assess the safety and efficacy of CKD-516, a novel vascular disrupting agent, in combination with Irinotecan in patients with previously treated metastatic colorectal cancer

Pharmacokinetics of Hydroxychloroquine and Its Clinical Implications in Chemoprophylaxis against Malaria Caused by Plasmodium vivax

Comprehensive Analysis of UGT1A Polymorphisms Predictive for Pharmacokinetics and Treatment Outcome in Patients With Non–Small-Cell Lung Cancer Treated With Irinotecan and Cisplatin

Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan‐pharmacokinetics and clinical outcome in patients with advanced non‐small cell lung cancer

Pharmacokinetic equivalence of CT‐P17 to high‐concentration (100 mg/ml) reference adalimumab: A randomized phase I study in healthy subjects

A Phase I/IIa Study of DHP107, a Novel Oral Paclitaxel Formulation, in Patients with Advanced Solid Tumors or Gastric Cancer

Impact of CYP2D6, CYP3A5, CYP2C19, CYP2A6, SLCO1B1, ABCB1, and ABCG2 gene polymorphisms on the pharmacokinetics of simvastatin and simvastatin acid

Pharmacokinetic and Pharmacodynamic Modeling and Simulation Analysis of Prasugrel in Healthy Male Volunteers

Effects of Renal Impairment on the Pharmacokinetics and Safety of Udenafil

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