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Basics and recent advances in peptide and protein drug delivery

Therapeutic delivery, 2013-11, Vol.4 (11), p.1443-1467

2013

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The Challenges and Prospects of p53-Based Therapies in Ovarian Cancer

Biomolecules (Basel, Switzerland), 2023-01, Vol.13 (1), p.159

2023

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Computational Modeling of Stapled Peptides toward a Treatment Strategy for CML and Broader Implications in the Design of Lengthy Peptide Therapeutics

The journal of physical chemistry. B, 2018-04, Vol.122 (14), p.3864-3875

2018

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Narrowing the field: cancer-specific promoters for mitochondrially-targeted p53-BH3 fusion gene therapy in ovarian cancer

Journal of ovarian research, 2019-04, Vol.12 (1), p.38-38, Article 38

2019

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Delivery of drugs and macromolecules to the mitochondria for cancer therapy

Journal of controlled release, 2016-10, Vol.240, p.38-51

2016

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A Single Mutant, A276S of p53, Turns the Switch to Apoptosis

Molecular pharmaceutics, 2013-04, Vol.10 (4), p.1350-1359

2013

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Development of an effective therapy for chronic myelogenous leukemia

The cancer journal (Sudbury, Mass.), 2011-11, Vol.17 (6), p.477-486

2011

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Mapping the Evidence for Opioid-Mediated Changes in Malignancy and Chemotherapeutic Efficacy: Protocol for a Scoping Review

JMIR research protocols, 2023-05, Vol.12, p.e38167-e38167

2023

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Mitochondrially targeted p53 or DBD subdomain is superior to wild type p53 in ovarian cancer cells even with strong dominant negative mutant p53

Journal of ovarian research, 2019-05, Vol.12 (1), p.45-45, Article 45

2019

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Disruption of Bcr-Abl Coiled Coil Oligomerization by Design

The Journal of biological chemistry, 2011-08, Vol.286 (31), p.27751-27760

2011

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Solid phase synthesis of mitochondrial triphenylphosphonium-vitamin E metabolite using a lysine linker for reversal of oxidative stress

PloS one, 2013-01, Vol.8 (1), p.e53272-e53272

2013

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Roadmap to affinity-tuned antibodies for enhanced chimeric antigen receptor T cell function and selectivity

Trends in biotechnology (Regular ed.), 2022-07, Vol.40 (7), p.875-890

2022

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Selective Targeting of c-Abl via a Cryptic Mitochondrial Targeting Signal Activated by Cellular Redox Status in Leukemic and Breast Cancer Cells

Pharmaceutical research, 2012-08, Vol.29 (8), p.2317-2328

2012

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The nuclear translocation assay for intracellular protein-protein interactions and its application to the Bcr coiled-coil domain

BioTechniques, 2010-07, Vol.49 (1), p.519-524

2010

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Molecular Modeling of Single- and Double-Hydrocarbon-Stapled Coiled-Coil Inhibitors against Bcr-Abl: Toward a Treatment Strategy for CML

The journal of physical chemistry. B, 2024-07, Vol.128 (27), p.6476-6491

2024

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Controlling subcellular localization to alter function: Sending oncogenic Bcr– Abl to the nucleus causes apoptosis

Journal of controlled release, 2009-12, Vol.140 (3), p.245-249

2009

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Abstract 3500: Mitochondrially targeted p53 domains as a stand alone or adjunct to paclitaxel for the treatment of ovarian cancer

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.3500-3500

2016

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Systematic single amino acid affinity tuning of CD229 CAR T cells retains efficacy against multiple myeloma and eliminates on-target off-tumor toxicity

Science translational medicine, 2023-07, Vol.15 (705), p.eadd7900

2023

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Application of Thiol–yne/Thiol–ene Reactions for Peptide and Protein Macrocyclizations

Chemistry : a European journal, 2017-05, Vol.23 (29), p.7087-7092

2017

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Delivery of a Monomeric p53 Subdomain with Mitochondrial Targeting Signals from Pro-Apoptotic Bak or Bax

Pharmaceutical research, 2014-09, Vol.31 (9), p.2503-2515

2014

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Trafficking of nuclear receptors in living cells

Journal of steroid biochemistry and molecular biology, 2000-11, Vol.74 (5), p.249-254

2000

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p53-Bad Fusion Gene Therapy Induces Apoptosis In Vitro and Reduces Zebrafish Tumor Burden in Hepatocellular Carcinoma

Molecular pharmaceutics, 2023-01, Vol.20 (1), p.331-340

2023

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Resistant mutations in CML and Ph+ALL - role of ponatinib

Biologics, 2014-01, Vol.8 (default), p.243-253

2014

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p53-Bad: A Novel Tumor Suppressor/Proapoptotic Factor Hybrid Directed to the Mitochondria for Ovarian Cancer Gene Therapy

Molecular pharmaceutics, 2019-08, Vol.16 (8), p.3386-3398

2019

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The DNA Binding Domain of p53 Is Sufficient To Trigger a Potent Apoptotic Response at the Mitochondria

Molecular pharmaceutics, 2013-10, Vol.10 (10), p.3592-3602

2013

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Basics and recent advances in peptide and protein drug delivery

The Challenges and Prospects of p53-Based Therapies in Ovarian Cancer

Computational Modeling of Stapled Peptides toward a Treatment Strategy for CML and Broader Implications in the Design of Lengthy Peptide Therapeutics

Narrowing the field: cancer-specific promoters for mitochondrially-targeted p53-BH3 fusion gene therapy in ovarian cancer

Delivery of drugs and macromolecules to the mitochondria for cancer therapy

A Single Mutant, A276S of p53, Turns the Switch to Apoptosis

Development of an effective therapy for chronic myelogenous leukemia

Mapping the Evidence for Opioid-Mediated Changes in Malignancy and Chemotherapeutic Efficacy: Protocol for a Scoping Review

Mitochondrially targeted p53 or DBD subdomain is superior to wild type p53 in ovarian cancer cells even with strong dominant negative mutant p53

Disruption of Bcr-Abl Coiled Coil Oligomerization by Design

Solid phase synthesis of mitochondrial triphenylphosphonium-vitamin E metabolite using a lysine linker for reversal of oxidative stress

Roadmap to affinity-tuned antibodies for enhanced chimeric antigen receptor T cell function and selectivity

Selective Targeting of c-Abl via a Cryptic Mitochondrial Targeting Signal Activated by Cellular Redox Status in Leukemic and Breast Cancer Cells

The nuclear translocation assay for intracellular protein-protein interactions and its application to the Bcr coiled-coil domain

Molecular Modeling of Single- and Double-Hydrocarbon-Stapled Coiled-Coil Inhibitors against Bcr-Abl: Toward a Treatment Strategy for CML

Controlling subcellular localization to alter function: Sending oncogenic Bcr– Abl to the nucleus causes apoptosis

Abstract 3500: Mitochondrially targeted p53 domains as a stand alone or adjunct to paclitaxel for the treatment of ovarian cancer

Systematic single amino acid affinity tuning of CD229 CAR T cells retains efficacy against multiple myeloma and eliminates on-target off-tumor toxicity

Application of Thiol–yne/Thiol–ene Reactions for Peptide and Protein Macrocyclizations

Delivery of a Monomeric p53 Subdomain with Mitochondrial Targeting Signals from Pro-Apoptotic Bak or Bax

Trafficking of nuclear receptors in living cells

p53-Bad Fusion Gene Therapy Induces Apoptosis In Vitro and Reduces Zebrafish Tumor Burden in Hepatocellular Carcinoma

Resistant mutations in CML and Ph+ALL - role of ponatinib

p53-Bad: A Novel Tumor Suppressor/Proapoptotic Factor Hybrid Directed to the Mitochondria for Ovarian Cancer Gene Therapy

The DNA Binding Domain of p53 Is Sufficient To Trigger a Potent Apoptotic Response at the Mitochondria

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