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Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function

PLoS pathogens, 2017-02, Vol.13 (2), p.e1006206-e1006206

2017

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Efficient TALEN-mediated gene knockout in livestock

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (43), p.17382-17387

2012

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Engineering large animal models of human disease

The Journal of pathology, 2016-01, Vol.238 (2), p.247-256

2016

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GARP and EARP are required for efficient BoHV-1 replication as identified by a genome wide CRISPR knockout screen

PLoS pathogens, 2023-12, Vol.19 (12), p.e1011822-e1011822

2023

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Generation of germline ablated male pigs by CRISPR/Cas9 editing of the NANOS2 gene

Scientific reports, 2017-01, Vol.7 (1), p.40176-40176, Article 40176

2017

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Highly efficient targeted chromosome deletions using CRISPR/Cas9

Biotechnology and bioengineering, 2015-05, Vol.112 (5), p.1060-1064

2015

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Cross-species efficacy of enzyme replacement therapy for CLN1 disease in mice and sheep

The Journal of clinical investigation, 2022-10, Vol.132 (20), p.1-11

2022

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Efficient production of germline transgenic chickens using lentiviral vectors

EMBO reports, 2004-07, Vol.5 (7), p.728-733

2004

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Localised axial progenitor cell populations in the avian tail bud are not committed to a posterior Hox identity

Development (Cambridge), 2008-07, Vol.135 (13), p.2289-2299

2008

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Species-Specific Variation in RELA Underlies Differences in NF-κB Activity: a Potential Role in African Swine Fever Pathogenesis

Journal of Virology, 2011-06, Vol.85 (12), p.6008-6014

2011

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Pigs Lacking the Scavenger Receptor Cysteine-Rich Domain 5 of CD163 Are Resistant to Porcine Reproductive and Respiratory Syndrome Virus 1 Infection

Journal of virology, 2018-08, Vol.92 (16)

2018

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Gene targeting, genome editing: from Dolly to editors

Transgenic research, 2016-06, Vol.25 (3), p.273-287

2016

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Gene targeting, genome editing: from Dolly to editors

Transgenic Research, 2016-06, Vol.25 (3), p.273-287

2016

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CRISPR-Based Gene Drives for Pest Control

Trends in biotechnology (Regular ed.), 2018-02, Vol.36 (2), p.130-133

2018

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Transgenic chickens as bioreactors for protein-based drugs

Drug Discovery Today, 2005-02, Vol.10 (3), p.191-196

2005

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Modelling Neurological Diseases in Large Animals: Criteria for Model Selection and Clinical Assessment

Cells (Basel, Switzerland), 2022-08, Vol.11 (17), p.2641

2022

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Genome edited sheep and cattle

Transgenic research, 2015-02, Vol.24 (1), p.147-153

2015

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Site specific insertion of a transgene into the murine α‐casein (CSN1S1) gene results in the predictable expression of a recombinant protein in milk

Biotechnology journal, 2024-01, Vol.19 (2), p.e2300287-n/a

2024

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Live pigs produced from genome edited zygotes

Scientific reports, 2013-10, Vol.3 (1), p.2847-2847, Article 2847

2013

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Milk lacking α-casein leads to permanent reduction in body size in mice

PloS one, 2011, Vol.6 (7), p.e21775-e21775

2011

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Swine ANP32A Supports Avian Influenza Virus Polymerase

Journal of virology, 2020-06, Vol.94 (12)

2020

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Mammalian interspecies substitution of immune modulatory alleles by genome editing

Scientific reports, 2016-02, Vol.6 (1), p.21645-21645, Article 21645

2016

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Erratum for Burkard et al., “Pigs Lacking the Scavenger Receptor Cysteine-Rich Domain 5 of CD163 Are Resistant to Porcine Reproductive and Respiratory Syndrome Virus 1 Infection”

Journal of virology, 2020-07, Vol.94 (15)

2020

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Substitution of warthog NF-κB motifs into RELA of domestic pigs is not sufficient to confer resilience to African swine fever virus

Scientific reports, 2020-06, Vol.10 (1), p.8951-8951, Article 8951

2020

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Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function

Efficient TALEN-mediated gene knockout in livestock

Engineering large animal models of human disease

C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity

GARP and EARP are required for efficient BoHV-1 replication as identified by a genome wide CRISPR knockout screen

Generation of germline ablated male pigs by CRISPR/Cas9 editing of the NANOS2 gene

Highly efficient targeted chromosome deletions using CRISPR/Cas9

Cross-species efficacy of enzyme replacement therapy for CLN1 disease in mice and sheep

Efficient production of germline transgenic chickens using lentiviral vectors

Localised axial progenitor cell populations in the avian tail bud are not committed to a posterior Hox identity

Species-Specific Variation in RELA Underlies Differences in NF-κB Activity: a Potential Role in African Swine Fever Pathogenesis

Pigs Lacking the Scavenger Receptor Cysteine-Rich Domain 5 of CD163 Are Resistant to Porcine Reproductive and Respiratory Syndrome Virus 1 Infection

Gene targeting, genome editing: from Dolly to editors

Gene targeting, genome editing: from Dolly to editors

CRISPR-Based Gene Drives for Pest Control

Transgenic chickens as bioreactors for protein-based drugs

Modelling Neurological Diseases in Large Animals: Criteria for Model Selection and Clinical Assessment

Genome edited sheep and cattle

Site specific insertion of a transgene into the murine α‐casein (CSN1S1) gene results in the predictable expression of a recombinant protein in milk

Live pigs produced from genome edited zygotes

Milk lacking α-casein leads to permanent reduction in body size in mice

Swine ANP32A Supports Avian Influenza Virus Polymerase

Mammalian interspecies substitution of immune modulatory alleles by genome editing

Erratum for Burkard et al., “Pigs Lacking the Scavenger Receptor Cysteine-Rich Domain 5 of CD163 Are Resistant to Porcine Reproductive and Respiratory Syndrome Virus 1 Infection”

Substitution of warthog NF-κB motifs into RELA of domestic pigs is not sufficient to confer resilience to African swine fever virus

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