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Molecular mechanisms of cell death in neurological diseases

Cell death and differentiation, 2021-07, Vol.28 (7), p.2029-2044

2021

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Are Astrocytes the Predominant Cell Type for Activation of Nrf2 in Aging and Neurodegeneration?

Antioxidants, 2017-08, Vol.6 (3), p.65

Liddell, Jeffrey R

2017

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Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration

Frontiers in neuroscience, 2018-07, Vol.12, p.466-466

2018

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Neuron-astrocyte transmitophagy is altered in Alzheimer's disease

Neurobiology of disease, 2022-08, Vol.170, p.105753-105753, Article 105753

2022

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Evidence for disrupted copper availability in human spinal cord supports CuII(atsm) as a treatment option for sporadic cases of ALS

Scientific reports, 2024-03, Vol.14 (1), p.5929-5929, Article 5929

2024

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Regular Physical Exercise Modulates Iron Homeostasis in the 5xFAD Mouse Model of Alzheimer’s Disease

International journal of molecular sciences, 2021-08, Vol.22 (16), p.8715

2021

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Copper-ATSM as a Treatment for ALS: Support from Mutant SOD1 Models and Beyond

Life (Basel, Switzerland), 2020-11, Vol.10 (11), p.271

2020

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impaired mitochondrial electron transport chain increases retention of the hypoxia imaging agent diacetylbis(4-methylthiosemicarbazonato)copperII

Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (1), p.47-52

2012

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Novel Anti-Neuroinflammatory Properties of a Thiosemicarbazone–Pyridylhydrazone Copper(II) Complex

International journal of molecular sciences, 2022-09, Vol.23 (18), p.10722

2022

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Neuroprotective copper bis(thiosemicarbazonato) complexes promote neurite elongation

PloS one, 2014-02, Vol.9 (2), p.e90070-e90070

2014

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Biometal Dyshomeostasis in Olfactory Mucosa of Alzheimer's Disease Patients

International journal of molecular sciences, 2022-04, Vol.23 (8), p.4123

2022

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Microglial ferroptotic stress causes non-cell autonomous neuronal death

Molecular neurodegeneration, 2024-02, Vol.19 (1), p.14-14, Article 14

2024

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Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress

PloS one, 2013-06, Vol.8 (6), p.e67433

2013

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Inhibition of TDP-43 accumulation by bis(thiosemicarbazonato)-copper complexes

PloS one, 2012-08, Vol.7 (8), p.e42277

2012

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Phosphorylation of hnRNP K by cyclin-dependent kinase 2 controls cytosolic accumulation of TDP-43

Human molecular genetics, 2015-03, Vol.24 (6), p.1655-1669

2015

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ZnII (atsm) is protective in amyotrophic lateral sclerosis model mice via a copper delivery mechanism

Neurobiology of disease, 2015-09, Vol.81, p.20-24

2015

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C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress

Molecular neurodegeneration, 2011-08, Vol.6 (1), p.57-57, Article 57

2011

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Therapeutic effects of CuII(atsm) in the SOD1-G37R mouse model of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis and frontotemporal degeneration, 2013-12, Vol.14 (7-8), p.586-590

2013

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CuII(atsm) Attenuates Neuroinflammation

Frontiers in neuroscience, 2018-09, Vol.12, p.668-668

2018

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Nexus between mitochondrial function, iron, copper and glutathione in Parkinson's disease

Neurochemistry international, 2018-07, Vol.117, p.126-138

2018

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CuII(atsm) significantly decreases microglial reactivity in patients with sporadic amyotrophic lateral sclerosis

Neuropathology and applied neurobiology, 2023-10, Vol.49 (5), p.e12938-n/a

2023

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Cu II (atsm) significantly decreases microglial reactivity in patients with sporadic amyotrophic lateral sclerosis

Neuropathology and applied neurobiology, 2023-10, Vol.49 (5), p.e12938

2023

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Fundamental Neurochemistry Review: Copper availability as a potential therapeutic target in progressive supranuclear palsy: Insight from other neurodegenerative diseases

Journal of neurochemistry, 2023-11, Vol.167 (3), p.337-346

2023

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TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway

Human molecular genetics, 2017-05, Vol.26 (9), p.1732-1746

2017

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Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder

Acta neuropathologica communications, 2014-02, Vol.2 (1), p.25-25, Article 25

2014

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Molecular mechanisms of cell death in neurological diseases

Are Astrocytes the Predominant Cell Type for Activation of Nrf2 in Aging and Neurodegeneration?

Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration

Neuron-astrocyte transmitophagy is altered in Alzheimer's disease

Evidence for disrupted copper availability in human spinal cord supports CuII(atsm) as a treatment option for sporadic cases of ALS

Regular Physical Exercise Modulates Iron Homeostasis in the 5xFAD Mouse Model of Alzheimer’s Disease

Copper-ATSM as a Treatment for ALS: Support from Mutant SOD1 Models and Beyond

impaired mitochondrial electron transport chain increases retention of the hypoxia imaging agent diacetylbis(4-methylthiosemicarbazonato)copperII

Novel Anti-Neuroinflammatory Properties of a Thiosemicarbazone–Pyridylhydrazone Copper(II) Complex

Neuroprotective copper bis(thiosemicarbazonato) complexes promote neurite elongation

Biometal Dyshomeostasis in Olfactory Mucosa of Alzheimer's Disease Patients

Microglial ferroptotic stress causes non-cell autonomous neuronal death

Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress

Inhibition of TDP-43 accumulation by bis(thiosemicarbazonato)-copper complexes

Phosphorylation of hnRNP K by cyclin-dependent kinase 2 controls cytosolic accumulation of TDP-43

ZnII (atsm) is protective in amyotrophic lateral sclerosis model mice via a copper delivery mechanism

C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress

Therapeutic effects of CuII(atsm) in the SOD1-G37R mouse model of amyotrophic lateral sclerosis

CuII(atsm) Attenuates Neuroinflammation

Nexus between mitochondrial function, iron, copper and glutathione in Parkinson's disease

CuII(atsm) significantly decreases microglial reactivity in patients with sporadic amyotrophic lateral sclerosis

Cu II (atsm) significantly decreases microglial reactivity in patients with sporadic amyotrophic lateral sclerosis

Fundamental Neurochemistry Review: Copper availability as a potential therapeutic target in progressive supranuclear palsy: Insight from other neurodegenerative diseases

TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway

Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder

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