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Broad Programming by IL-2 Receptor Signaling for Extended Growth to Multiple Cytokines and Functional Maturation of Antigen-Activated T Cells

The Journal of immunology (1950), 2001-02, Vol.166 (3), p.1675-1683

2001

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Structure and function of human perforin

Nature (London), 1988-09, Vol.335 (6189), p.448-451

1988

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A Central Role of Perforin in Cytolysis?

Annual review of immunology, 1991-01, Vol.9 (1), p.129-157

1991

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Interleukin-2 and Inflammation Induce Distinct Transcriptional Programs that Promote the Differentiation of Effector Cytolytic T Cells

Immunity (Cambridge, Mass.), 2010-01, Vol.32 (1), p.79-90

2010

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A role for NF-kappa B activation in perforin expression of NK cells upon IL-2 receptor signaling

The Journal of immunology (1950), 2002-08, Vol.169 (3), p.1319-1325

2002

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Interleukin 2 receptor signaling regulates the perforin gene through signal transducer and activator of transcription (Stat)5 activation of two enhancers

The Journal of experimental medicine, 1999-11, Vol.190 (9), p.1297-1308

1999

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Cytolysis by Ca-permeable transmembrane channels: pore formation causes extensive DNA degradation and cell lysis

The Journal of experimental medicine, 1989-03, Vol.169 (3), p.765-777

1989

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Structure and function of the murine perforin promoter and upstream region. Reciprocal gene activation or silencing in perforin positive and negative cells

The Journal of immunology (1950), 1992-10, Vol.149 (8), p.2619-2626

1992

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Structure of the human perforin gene. A simple gene organization with interesting potential regulatory sequences

The Journal of immunology (1950), 1989-12, Vol.143 (12), p.4267-4274

1989

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Perforin expression in human peripheral blood mononuclear cells. Definition of an IL-2-independent pathway of perforin induction in CD8+ T cells

The Journal of immunology (1950), 1992-06, Vol.148 (11), p.3354-3360

1992

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Perforin and granzyme B as markers for acute rejection in heart transplantation

International immunology, 1991-11, Vol.3 (11), p.1175-1181

1991

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Non-killer cell-specific transcription factors silence the perforin promoter

The Journal of immunology (1950), 1997-02, Vol.158 (4), p.1734-1741

1997

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Potent Inhibition of CTLA-4 Expression by an Anti-CTLA-4 Ribozyme

Biochemical and biophysical research communications, 1998-06, Vol.247 (3), p.838-843

1998

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Characterization of a R115777-Resistant Human Multiple Myeloma Cell Line with Cross-Resistance to PS-341

Clinical cancer research, 2005-08, Vol.11 (16), p.6057-6064

2005

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Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells

Blood, 2005-06, Vol.105 (12), p.4759-4766

2005

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A reliable method to display authentic DNase I hypersensitive sites at long-ranges in single-copy genes from large genomes

Nucleic acids research, 2006-03, Vol.34 (4), p.e34-e34

2006

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R115777 induces Ras-independent apoptosis of myeloma cells via multiple intrinsic pathways

Molecular cancer therapeutics, 2004-02, Vol.3 (2), p.179-186

2004

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Transgenic control of perforin gene expression. Functional evidence for two separate control regions

The Journal of immunology (1950), 1995-03, Vol.154 (5), p.2153-2163

1995

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Farnesyl Transferase Inhibitors Enhance Death Receptor Signals and Induce Apoptosis in Multiple Myeloma Cells

Leukemia & lymphoma, 2003-12, Vol.44 (12), p.2123-2134

2003

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Perforin and the mechanism of lymphocyte-mediated cytolysis

Current topics in membranes and transport, 1990, Vol.36, p.161-175

1990

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Perforin-2 Breaches the Envelope of Phagocytosed Bacteria Allowing Antimicrobial Effectors Access to Intracellular Targets

The Journal of immunology (1950), 2018-11, Vol.201 (9), p.2710-2720

2018

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Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs

The Journal of experimental medicine, 2009-01, Vol.206 (1), p.51-59

2009

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Characterization of a R115777 Resistant Human Multiple Myeloma Cell Line with Cross-Resistance to PS-341

Blood, 2004-11, Vol.104 (11), p.3363-3363

2004

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Function of granule perforin and esterases in T cell-mediated reaction. Components required for delivery of molecules to target cells

Annals of the New York Academy of Sciences [ANN. N.Y. ACAD. SCI.]. 1988, 1988

1988

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Broad Programming by IL-2 Receptor Signaling for Extended Growth to Multiple Cytokines and Functional Maturation of Antigen-Activated T Cells

Structure and function of human perforin

A Central Role of Perforin in Cytolysis?

Interleukin-2 and Inflammation Induce Distinct Transcriptional Programs that Promote the Differentiation of Effector Cytolytic T Cells

A role for NF-kappa B activation in perforin expression of NK cells upon IL-2 receptor signaling

Interleukin 2 receptor signaling regulates the perforin gene through signal transducer and activator of transcription (Stat)5 activation of two enhancers

Cytolysis by Ca-permeable transmembrane channels: pore formation causes extensive DNA degradation and cell lysis

Structure and function of the murine perforin promoter and upstream region. Reciprocal gene activation or silencing in perforin positive and negative cells

Structure of the human perforin gene. A simple gene organization with interesting potential regulatory sequences

Perforin expression in human peripheral blood mononuclear cells. Definition of an IL-2-independent pathway of perforin induction in CD8+ T cells

Perforin and granzyme B as markers for acute rejection in heart transplantation

Non-killer cell-specific transcription factors silence the perforin promoter

Potent Inhibition of CTLA-4 Expression by an Anti-CTLA-4 Ribozyme

Characterization of a R115777-Resistant Human Multiple Myeloma Cell Line with Cross-Resistance to PS-341

Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells

A reliable method to display authentic DNase I hypersensitive sites at long-ranges in single-copy genes from large genomes

R115777 induces Ras-independent apoptosis of myeloma cells via multiple intrinsic pathways

Transgenic control of perforin gene expression. Functional evidence for two separate control regions

Farnesyl Transferase Inhibitors Enhance Death Receptor Signals and Induce Apoptosis in Multiple Myeloma Cells

Perforin and the mechanism of lymphocyte-mediated cytolysis

Perforin-2 Breaches the Envelope of Phagocytosed Bacteria Allowing Antimicrobial Effectors Access to Intracellular Targets

Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs

Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria

Characterization of a R115777 Resistant Human Multiple Myeloma Cell Line with Cross-Resistance to PS-341

Function of granule perforin and esterases in T cell-mediated reaction. Components required for delivery of molecules to target cells

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