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Antisense oligonucleotide modulation of non-productive alternative splicing upregulates gene expression

Nature communications, 2020-07, Vol.11 (1), p.3501-13, Article 3501

2020

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Antagonism of sphingosine-1-phosphate receptors by FTY720 inhibits angiogenesis and tumor vascularization

Cancer research (Chicago, Ill.), 2006, Vol.66 (1), p.221-231

2006

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Relative Quantification of NaV1.1 Protein in Mouse Brains Using a Meso Scale Discovery-Electrochemiluminescence (MSD-ECL) Method

Bio-protocol, 2021-02, Vol.11 (3), p.e3910-e3910

2021

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Comparative effects of different modes of renin angiotensin system inhibition on hypercholesterolaemia‐induced atherosclerosis

British journal of pharmacology, 2012-03, Vol.165 (6), p.2000-2008

2012

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Secreted PCSK9 promotes LDL receptor degradation independently of proteolytic activity

Biochemical journal, 2007-09, Vol.406 (2), p.203-207

2007

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Antisense oligonucleotides increase Scn1a expression and reduce seizures and SUDEP incidence in a mouse model of Dravet syndrome

Science translational medicine, 2020-08, Vol.12 (558)

2020

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Inhibition of Choroidal Neovascularization by Intravenous Injection of Adenoviral Vectors Expressing Secretable Endostatin

The American journal of pathology, 2001-07, Vol.159 (1), p.313-320

2001

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Relative Quantification of Na V 1.1 Protein in Mouse Brains Using a Meso Scale Discovery-Electrochemiluminescence (MSD-ECL) Method

Bio-protocol, 2021-02, Vol.11 (3), p.e3910

2021

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Targeted Augmentation of Nuclear Gene Output (TANGO) of Scn1a rescues parvalbumin interneuron excitability and reduces seizures in a mouse model of Dravet Syndrome

Brain research, 2022-01, Vol.1775, p.147743-147743, Article 147743

2022

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Antisense Oligonucleotide STK-002 Increases OPA1 in Retina and Improves Mitochondrial Function in Autosomal Dominant Optic Atrophy Cells

Nucleic acid therapeutics, 2024-10, Vol.34 (5), p.221-233

2024

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Extracellular export of sphingosine kinase-1 enzyme. Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation

The Journal of biological chemistry, 2002-02, Vol.277 (8), p.6667-6675

2002

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Growth Factor and Cytokine-Regulated Hyaluronan-Binding Protein TSG-6 Is Localized to the Injury-Induced Rat Neointima and Confers Enhanced Growth in Vascular Smooth Muscle Cells

Circulation research, 1997-09, Vol.81 (3), p.289-296

1997

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138. Potential Therapeutic Treatment of Friedrich's Ataxia Using Highly Specific Engineered Meganucleases

Molecular therapy, 2016-05, Vol.24, p.S56-S56

2016

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Oxidized LDL mediates the release of fibroblast growth factor-1

Arteriosclerosis, thrombosis, and vascular biology, 1997-03, Vol.17 (3), p.445-453

1997

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Intraocular expression of endostatin reduces VEGF‐induced retinal vascular permeability, neovascularization, and retinal detachment

The FASEB journal, 2003-05, Vol.17 (8), p.1-22

2003

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The New Angiotherapy

Drug discovery today, 2002-05, Vol.7 (11), p.599-600

Liau, Gene

2002

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Aliskiren inhibits atherosclerosis development and improves plaque stability in APOE3Leiden.CETP transgenic mice with or without treatment with atorvastatin

Journal of hypertension, 2012-01, Vol.30 (1), p.107-116

2012

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Extracellular Export of Sphingosine Kinase-1 Enzyme

The Journal of biological chemistry, 2002-02, Vol.277 (8), p.6667-6675

2002

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Evidence for apoptosis in human atherogenesis and in a rat vascular injury model

The American journal of pathology, 1995-08, Vol.147 (2), p.267-277

1995

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Gene therapy vector-mediated expression of insulin-like growth factors protects cardiomyocytes from apoptosis and enhances neovascularization

American journal of physiology. Heart and circulatory physiology, 2003-04, Vol.284 (4), p.H1429-H1440

2003

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Internalization but not binding of thrombospondin-1 to low density lipoprotein receptor-related protein-1 requires heparan sulfate proteoglycans

Journal of cellular biochemistry, 2004-03, Vol.91 (4), p.766-776

2004

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Identification of the Low Density Lipoprotein Receptor-Related Protein (LRP) as an Endocytic Receptor for Thrombospondin-1

The Journal of cell biology, 1995-06, Vol.129 (5), p.1403-1410

1995

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Cellular Internalization and Degradation of Thrombospondin-1 Is Mediated by the Amino-terminal Heparin Binding Domain (HBD)

The Journal of biological chemistry, 1997-03, Vol.272 (10), p.6784-6791

1997

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Gene Therapy for Antiangiogenesis

JNCI : Journal of the National Cancer Institute, 2001-07, Vol.93 (13), p.965-967

2001

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Imprinted mesodermal specific transcript (MEST) and H19 genes in renal development and diabetes

Kidney international, 2003-05, Vol.63 (5), p.1658-1670

2003

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Antisense oligonucleotide modulation of non-productive alternative splicing upregulates gene expression

Antagonism of sphingosine-1-phosphate receptors by FTY720 inhibits angiogenesis and tumor vascularization

Relative Quantification of NaV1.1 Protein in Mouse Brains Using a Meso Scale Discovery-Electrochemiluminescence (MSD-ECL) Method

Comparative effects of different modes of renin angiotensin system inhibition on hypercholesterolaemia‐induced atherosclerosis

Secreted PCSK9 promotes LDL receptor degradation independently of proteolytic activity

Antisense oligonucleotides increase Scn1a expression and reduce seizures and SUDEP incidence in a mouse model of Dravet syndrome

Inhibition of Choroidal Neovascularization by Intravenous Injection of Adenoviral Vectors Expressing Secretable Endostatin

Relative Quantification of Na V 1.1 Protein in Mouse Brains Using a Meso Scale Discovery-Electrochemiluminescence (MSD-ECL) Method

Targeted Augmentation of Nuclear Gene Output (TANGO) of Scn1a rescues parvalbumin interneuron excitability and reduces seizures in a mouse model of Dravet Syndrome

Antisense Oligonucleotide STK-002 Increases OPA1 in Retina and Improves Mitochondrial Function in Autosomal Dominant Optic Atrophy Cells

Extracellular export of sphingosine kinase-1 enzyme. Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation

Growth Factor and Cytokine-Regulated Hyaluronan-Binding Protein TSG-6 Is Localized to the Injury-Induced Rat Neointima and Confers Enhanced Growth in Vascular Smooth Muscle Cells

138. Potential Therapeutic Treatment of Friedrich's Ataxia Using Highly Specific Engineered Meganucleases

Oxidized LDL mediates the release of fibroblast growth factor-1

Intraocular expression of endostatin reduces VEGF‐induced retinal vascular permeability, neovascularization, and retinal detachment

The New Angiotherapy

Aliskiren inhibits atherosclerosis development and improves plaque stability in APOE3Leiden.CETP transgenic mice with or without treatment with atorvastatin

Extracellular Export of Sphingosine Kinase-1 Enzyme

Evidence for apoptosis in human atherogenesis and in a rat vascular injury model

Gene therapy vector-mediated expression of insulin-like growth factors protects cardiomyocytes from apoptosis and enhances neovascularization

Internalization but not binding of thrombospondin-1 to low density lipoprotein receptor-related protein-1 requires heparan sulfate proteoglycans

Identification of the Low Density Lipoprotein Receptor-Related Protein (LRP) as an Endocytic Receptor for Thrombospondin-1

Cellular Internalization and Degradation of Thrombospondin-1 Is Mediated by the Amino-terminal Heparin Binding Domain (HBD)

Gene Therapy for Antiangiogenesis

Imprinted mesodermal specific transcript (MEST) and H19 genes in renal development and diabetes

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