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Arene Ruthenium(II) Complexes as Low-Toxicity Inhibitor against the Proliferation, Migration, and Invasion of MDA-MB-231 Cells through Binding and Stabilizing c‑myc G‑Quadruplex DNA

Organometallics, 2016-02, Vol.35 (3), p.317-326

2016

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Identification of Novel PPARγ Partial Agonists Based on Virtual Screening Strategy: In Silico and In Vitro Experimental Validation

Molecules (Basel, Switzerland), 2024-10, Vol.29 (20), p.4881

2024

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Gambogic Acid Induces Apoptosis in Imatinib-Resistant Chronic Myeloid Leukemia Cells via Inducing Proteasome Inhibition and Caspase-Dependent Bcr-Abl Downregulation

Clinical cancer research, 2014-01, Vol.20 (1), p.151-163

2014

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Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth

Oncotarget, 2014-07, Vol.5 (14), p.5453-5471

2014

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To Probe Full and Partial Activation of Human Peroxisome Proliferator-Activated Receptors by Pan-Agonist Chiglitazar Using Molecular Dynamics Simulations

PPAR research, 2020, Vol.2020 (2020), p.1-24

2020

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L-carnitine is an endogenous HDAC inhibitor selectively inhibiting cancer cell growth in vivo and in vitro

PloS one, 2012-11, Vol.7 (11), p.e49062

2012

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Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms

Oncotarget, 2014-10, Vol.5 (19), p.9118-9132

2014

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Stabilization of MYC G-quadruplex DNA by ruthenium (II) complex overcomes imatinib resistance in chronic myeloid leukemia cells harboring T315I mutation

Genes & diseases, 2023-03, Vol.10 (2), p.399-402

2023

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Gambogic Acid Is a Tissue-Specific Proteasome Inhibitor In Vitro and In Vivo

Cell reports (Cambridge), 2013-01, Vol.3 (1), p.211-222

2013

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Synthesis of active iron-based electrocatalyst for the oxygen reduction reaction and its unique electrochemical response in alkaline medium

Electrochimica acta, 2012-08, Vol.76, p.430-439

2012

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HDAC inhibitor L-carnitine and proteasome inhibitor bortezomib synergistically exert anti-tumor activity in vitro and in vivo

PloS one, 2012-12, Vol.7 (12), p.e52576

2012

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To Probe the Binding Interactions between Two FDA Approved Migraine Drugs (Ubrogepant and Rimegepant) and Calcitonin-Gene Related Peptide Receptor (CGRPR) Using Molecular Dynamics Simulations

ACS chemical neuroscience, 2021-07, Vol.12 (14), p.2629-2642

2021

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Identification of HPCAL1 as a specific autophagy receptor involved in ferroptosis

Autophagy, 2023-01, Vol.19 (1), p.54-74

2023

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Interaction analyses of hTAAR1 and mTAAR1 with antagonist EPPTB

Life sciences (1973), 2022-07, Vol.300, p.120553-120553, Article 120553

2022

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Analysis of vismodegib resistance in D473G and W535L mutants of SMO receptor and design of novel drug derivatives using molecular dynamics simulations

Life sciences (1973), 2020-03, Vol.244, p.117302-117302, Article 117302

2020

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Probing biased activation of mu-opioid receptor by the biased agonist PZM21 using all atom molecular dynamics simulation

Life sciences (1973), 2021-03, Vol.269, p.119026, Article 119026

2021

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High-order self-assembly of G-quadruplex DNA: Nano-network formation under the guidance of arene ruthenium(II) complexes

Journal of inorganic biochemistry, 2018-12, Vol.189, p.81-90

2018

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Microwave-assisted synthesis of phenanthroimidazole derivatives as stabilizer of c-myc G-quadruplex DNA

Bioorganic & medicinal chemistry, 2014-11, Vol.22 (22), p.6503-6508

2014

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Binding of agonist WAY-267,464 and antagonist WAY-methylated to oxytocin receptor probed by all-atom molecular dynamics simulations

Life sciences (1973), 2020-07, Vol.252, p.117643-16, Article 117643

2020

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Piperlongumine overcomes imatinib resistance by inducing proteasome inhibition in chronic myelogenous leukemia cells

Journal of ethnopharmacology, 2023-01, Vol.301, p.115815-115815, Article 115815

2023

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Study on the binding mode of a pyrrolotriazin derivative with JAK2 by docking and MD simulation

Molecular simulation, 2019-02, Vol.45 (3), p.230-238

2019

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Platinum-containing compound platinum pyrithione is stronger and safer than cisplatin in cancer therapy

Biochemical pharmacology, 2016-09, Vol.116, p.22-38

2016

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A Theoretical Study on the Hydrolysis Process of the Antimetastatic Ruthenium(III) Complex NAMI-A

The journal of physical chemistry. B, 2007-07, Vol.111 (27), p.7862-7869

2007

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3-O-(Z)-coumaroyloleanolic acid overcomes Cks1b-induced chemoresistance in lung cancer by inhibiting Hsp90 and MEK pathways

Biochemical pharmacology, 2017-07, Vol.135, p.35-49

2017

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Cadmium pyrithione suppresses tumor growth in vitro and in vivo through inhibition of proteasomal deubiquitinase

Biometals, 2018-02, Vol.31 (1), p.29-43

2018

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Arene Ruthenium(II) Complexes as Low-Toxicity Inhibitor against the Proliferation, Migration, and Invasion of MDA-MB-231 Cells through Binding and Stabilizing c‑myc G‑Quadruplex DNA

Identification of Novel PPARγ Partial Agonists Based on Virtual Screening Strategy: In Silico and In Vitro Experimental Validation

Gambogic Acid Induces Apoptosis in Imatinib-Resistant Chronic Myeloid Leukemia Cells via Inducing Proteasome Inhibition and Caspase-Dependent Bcr-Abl Downregulation

Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth

To Probe Full and Partial Activation of Human Peroxisome Proliferator-Activated Receptors by Pan-Agonist Chiglitazar Using Molecular Dynamics Simulations

L-carnitine is an endogenous HDAC inhibitor selectively inhibiting cancer cell growth in vivo and in vitro

Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms

Stabilization of MYC G-quadruplex DNA by ruthenium (II) complex overcomes imatinib resistance in chronic myeloid leukemia cells harboring T315I mutation

Gambogic Acid Is a Tissue-Specific Proteasome Inhibitor In Vitro and In Vivo

Synthesis of active iron-based electrocatalyst for the oxygen reduction reaction and its unique electrochemical response in alkaline medium

HDAC inhibitor L-carnitine and proteasome inhibitor bortezomib synergistically exert anti-tumor activity in vitro and in vivo

To Probe the Binding Interactions between Two FDA Approved Migraine Drugs (Ubrogepant and Rimegepant) and Calcitonin-Gene Related Peptide Receptor (CGRPR) Using Molecular Dynamics Simulations

Identification of HPCAL1 as a specific autophagy receptor involved in ferroptosis

Interaction analyses of hTAAR1 and mTAAR1 with antagonist EPPTB

Analysis of vismodegib resistance in D473G and W535L mutants of SMO receptor and design of novel drug derivatives using molecular dynamics simulations

Probing biased activation of mu-opioid receptor by the biased agonist PZM21 using all atom molecular dynamics simulation

High-order self-assembly of G-quadruplex DNA: Nano-network formation under the guidance of arene ruthenium(II) complexes

Microwave-assisted synthesis of phenanthroimidazole derivatives as stabilizer of c-myc G-quadruplex DNA

Binding of agonist WAY-267,464 and antagonist WAY-methylated to oxytocin receptor probed by all-atom molecular dynamics simulations

Piperlongumine overcomes imatinib resistance by inducing proteasome inhibition in chronic myelogenous leukemia cells

Study on the binding mode of a pyrrolotriazin derivative with JAK2 by docking and MD simulation

Platinum-containing compound platinum pyrithione is stronger and safer than cisplatin in cancer therapy

A Theoretical Study on the Hydrolysis Process of the Antimetastatic Ruthenium(III) Complex NAMI-A

3-O-(Z)-coumaroyloleanolic acid overcomes Cks1b-induced chemoresistance in lung cancer by inhibiting Hsp90 and MEK pathways

Cadmium pyrithione suppresses tumor growth in vitro and in vivo through inhibition of proteasomal deubiquitinase

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