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Ovarian cancer spheroid cells with stem cell-like properties contribute to tumor generation, metastasis and chemotherapy resistance through hypoxia-resistant metabolism

PloS one, 2014-01, Vol.9 (1), p.e84941

2014

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Effects of 1-methyltryptophan stereoisomers on IDO2 enzyme activity and IDO2-mediated arrest of human T cell proliferation

Cancer Immunology, Immunotherapy, 2012-11, Vol.61 (11), p.2013-2020

2012

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An ABCG2 non-substrate anticancer agent FL118 targets drug-resistant cancer stem-like cells and overcomes treatment resistance of human pancreatic cancer

Journal of experimental & clinical cancer research, 2018-10, Vol.37 (1), p.240-240, Article 240

2018

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Efficacy of Levo-1-Methyl Tryptophan and Dextro-1-Methyl Tryptophan in Reversing Indoleamine-2,3-Dioxygenase-Mediated Arrest of T-Cell Proliferation in Human Epithelial Ovarian Cancer

Cancer research (Chicago, Ill.), 2009-07, Vol.69 (13), p.5498-5504

2009

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Mutant Kras as a Biomarker Plays a Favorable Role in FL118-Induced Apoptosis, Reactive Oxygen Species (ROS) Production and Modulation of Survivin, Mcl-1 and XIAP in Human Bladder Cancer

Cancers, 2020-11, Vol.12 (11), p.3413

2020

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FL118, acting as a ‘molecular glue degrader’, binds to dephosphorylates and degrades the oncoprotein DDX5 (p68) to control c‐Myc, survivin and mutant Kras against colorectal and pancreatic cancer with high efficacy

Clinical and translational medicine, 2022-05, Vol.12 (5), p.e881-n/a

2022

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Lagrange Multiplier Based Control Method to Optimize Efficiency for Four-switch Buck-Boost Converter Over Whole Operating Range

IEEE transactions on industrial electronics (1982), 2024-01, Vol.71 (1), p.1-11

2024

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Efficiency Optimization of Four-Switch Buck-Boost Converter Using Frequency-domain Analysis

IEEE transactions on transportation electrification, 2024-07, p.1-1

2024

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Abstract A35: Ovarian cancer stem cells subvert tumor-specific T cells by disrupting T cells’ metabolic fitness

Clinical cancer research, 2018-08, Vol.24 (15_Supplement), p.A35-A35

2018

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Sensitivity of colorectal or pancreatic cancers with high DDX5 and mutations in Kras and p53 genes to FL118 treatment

Journal of clinical oncology, 2020-05, Vol.38 (15_suppl), p.e16102-e16102

2020

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Role of mutant KRAS as a biomarker in FL118-induced apoptosis, reactive oxygen species (ROS) production and inhibition of survivin, Mcl-1 and XIAP in human bladder cancer

Journal of clinical oncology, 2020-05, Vol.38 (15_suppl), p.e15651-e15651

2020

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Kras mutation subtypes distinctly affect colorectal cancer cell sensitivity to FL118, a novel inhibitor of survivin, Mcl-1, XIAP, cIAP2 and MdmX

American journal of translational research, 2021-01, Vol.13 (7), p.7458-7474

2021

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A FAK scaffold inhibitor disrupts FAK and VEGFR-3 signaling and blocks melanoma growth by targeting both tumor and endothelial cells

Cell cycle (Georgetown, Tex.), 2014-08, Vol.13 (16), p.2542-2553

2014

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Topoisomerase I (Top1): a major target of FL118 for its antitumor efficacy or mainly involved in its side effects of hematopoietic toxicity?

American journal of cancer research, 2017-01, Vol.7 (2), p.370-382

2017

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Targeting the C-terminal focal adhesion kinase scaffold in pancreatic cancer

Cancer letters, 2014-10, Vol.353 (2), p.281-289

2014

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Demonstration of the efficacy of compound CFAK-C4 targeting FAK-VEGFR3 protein-protein interaction in gastric cancer

Journal of clinical oncology, 2013-05, Vol.31 (15_suppl), p.e22143-e22143

2013

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The FAK scaffold inhibitor C4 disrupts FAK-VEGFR-3 signaling and inhibits pancreatic cancer growth

Oncotarget, 2013-10, Vol.4 (10), p.1632-1646

2013

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Abstract B3: Anti-angiogenic properties of FAK-VEGFR3 scaffold inhibitors, C9 and C10

Molecular cancer therapeutics, 2013-11, Vol.12 (11_Supplement), p.B3-B3

2013

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Abstract 3756: Structure activity relationship studies of novel FAK inhibitor C4

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.3756-3756

2012

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Abstract C124: Development of novel FAK inhibitors targeting the FAK-VEGFR3 protein-protein interaction site

Molecular cancer therapeutics, 2011-11, Vol.10 (11_Supplement), p.C124-C124

2011

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Expression and serum immunoreactivity of developmentally restricted differentiation antigens in epithelial ovarian cancer

Cancer immunity, 2009-08, Vol.9, p.6-6

2009

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High-strength deep learning image reconstruction in coronary CT angiography at 70-kVp tube voltage significantly improves image quality and reduces both radiation and contrast doses

European radiology, 2022-05, Vol.32 (5), p.2912-2920

2022

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Stability Analysis of Three-Dimensional Tunnel Face Considering Linear and Nonlinear Strength in Unsaturated Soil

Applied sciences, 2024-03, Vol.14 (5), p.2080

2024

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Analytical Solution for Seismic Stability of 3D Rock Slope Reinforced with Prestressed Anchor Cables

Applied sciences, 2024-05, Vol.14 (10), p.4160

2024

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Bone disease imaging through the near-infrared-II window

Nature communications, 2023-10, Vol.14 (1), p.6287-6287, Article 6287

2023

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Ovarian cancer spheroid cells with stem cell-like properties contribute to tumor generation, metastasis and chemotherapy resistance through hypoxia-resistant metabolism

Effects of 1-methyltryptophan stereoisomers on IDO2 enzyme activity and IDO2-mediated arrest of human T cell proliferation

An ABCG2 non-substrate anticancer agent FL118 targets drug-resistant cancer stem-like cells and overcomes treatment resistance of human pancreatic cancer

Efficacy of Levo-1-Methyl Tryptophan and Dextro-1-Methyl Tryptophan in Reversing Indoleamine-2,3-Dioxygenase-Mediated Arrest of T-Cell Proliferation in Human Epithelial Ovarian Cancer

Mutant Kras as a Biomarker Plays a Favorable Role in FL118-Induced Apoptosis, Reactive Oxygen Species (ROS) Production and Modulation of Survivin, Mcl-1 and XIAP in Human Bladder Cancer

FL118, acting as a ‘molecular glue degrader’, binds to dephosphorylates and degrades the oncoprotein DDX5 (p68) to control c‐Myc, survivin and mutant Kras against colorectal and pancreatic cancer with high efficacy

Lagrange Multiplier Based Control Method to Optimize Efficiency for Four-switch Buck-Boost Converter Over Whole Operating Range

Efficiency Optimization of Four-Switch Buck-Boost Converter Using Frequency-domain Analysis

Abstract A35: Ovarian cancer stem cells subvert tumor-specific T cells by disrupting T cells’ metabolic fitness

Sensitivity of colorectal or pancreatic cancers with high DDX5 and mutations in Kras and p53 genes to FL118 treatment

Role of mutant KRAS as a biomarker in FL118-induced apoptosis, reactive oxygen species (ROS) production and inhibition of survivin, Mcl-1 and XIAP in human bladder cancer

Kras mutation subtypes distinctly affect colorectal cancer cell sensitivity to FL118, a novel inhibitor of survivin, Mcl-1, XIAP, cIAP2 and MdmX

A FAK scaffold inhibitor disrupts FAK and VEGFR-3 signaling and blocks melanoma growth by targeting both tumor and endothelial cells

Topoisomerase I (Top1): a major target of FL118 for its antitumor efficacy or mainly involved in its side effects of hematopoietic toxicity?

Targeting the C-terminal focal adhesion kinase scaffold in pancreatic cancer

Demonstration of the efficacy of compound CFAK-C4 targeting FAK-VEGFR3 protein-protein interaction in gastric cancer

The FAK scaffold inhibitor C4 disrupts FAK-VEGFR-3 signaling and inhibits pancreatic cancer growth

Abstract B3: Anti-angiogenic properties of FAK-VEGFR3 scaffold inhibitors, C9 and C10

Abstract 3756: Structure activity relationship studies of novel FAK inhibitor C4

Abstract C124: Development of novel FAK inhibitors targeting the FAK-VEGFR3 protein-protein interaction site

Expression and serum immunoreactivity of developmentally restricted differentiation antigens in epithelial ovarian cancer

High-strength deep learning image reconstruction in coronary CT angiography at 70-kVp tube voltage significantly improves image quality and reduces both radiation and contrast doses

Stability Analysis of Three-Dimensional Tunnel Face Considering Linear and Nonlinear Strength in Unsaturated Soil

Analytical Solution for Seismic Stability of 3D Rock Slope Reinforced with Prestressed Anchor Cables

Bone disease imaging through the near-infrared-II window

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