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Small-Molecule Kinase Inhibitors for the Treatment of Nononcologic Diseases

Journal of medicinal chemistry, 2021-02, Vol.64 (3), p.1283-1345

2021

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Comparison of Nine Programs Predicting pKa Values of Pharmaceutical Substances

Journal of chemical information and modeling, 2009-12, Vol.49 (12), p.2801-2812

2009

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Design, synthesis and anticancer activities of novel dual poly(ADP-ribose) polymerase-1/histone deacetylase-1 inhibitors

Bioorganic & medicinal chemistry letters, 2020-04, Vol.30 (8), p.127036, Article 127036

2020

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From monoclonal antibodies to small molecules: the development of inhibitors targeting the PD-1/PD-L1 pathway

Drug discovery today, 2016-06, Vol.21 (6), p.1027-1036

2016

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Progress in the Discovery of Macrocyclic Histone Deacetylase Inhibitors for the Treatment of Cancer

Current medicinal chemistry, 2017-11, Vol.24 (37)

2017

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A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo

Molecular cancer therapeutics, 2014-03, Vol.13 (3), p.565-575

2014

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Inhibitors of the anti-apoptotic Bcl-2 proteins: a patent review

Expert opinion on therapeutic patents, 2012-01, Vol.22 (1), p.37-55

2012

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Publisher Correction: Intestinal Nogo-B reduces GLP1 levels by binding to proglucagon on the endoplasmic reticulum to inhibit PCSK1 cleavage

Nature communications, 2024-09, Vol.15 (1), p.7902-1, Article 7902

2024

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Ascorbic acid enhances low-density lipoprotein receptor expression by suppressing proprotein convertase subtilisin/kexin 9 expression

The Journal of biological chemistry, 2020-11, Vol.295 (47), p.15870-15882

2020

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Selective Histone Deacetylase Inhibitors with Anticancer Activity

Current topics in medicinal chemistry, 2016-01, Vol.16 (4), p.415-426

2016

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Intestinal Nogo-B reduces GLP1 levels by binding to proglucagon on the endoplasmic reticulum to inhibit PCSK1 cleavage

Nature communications, 2024-08, Vol.15 (1), p.6845-20, Article 6845

2024

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Discovery and Development of Cyclin-Dependent Kinase 8 Inhibitors

Current medicinal chemistry, 2020-01, Vol.27 (32), p.5429-5443

2020

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Design, synthesis, and biological evaluation of 1, 3-disubstituted-pyrazole derivatives as new class I and IIb histone deacetylase inhibitors

European journal of medicinal chemistry, 2014-10, Vol.86, p.639-652

2014

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NaoXinTong Capsule ameliorates memory deficit in APP/PS1 mice by regulating inflammatory cytokines

Biomedicine & pharmacotherapy, 2021-01, Vol.133, p.110964, Article 110964

2021

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Glabridin Ameliorates Alcohol-Caused Liver Damage by Reducing Oxidative Stress and Inflammation via p38 MAPK/Nrf2/NF-κB Pathway

Nutrients, 2023-04, Vol.15 (9), p.2157

2023

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Diversity evolution and jump of Polo-like kinase 1 inhibitors

Science China. Chemistry, 2013-10, Vol.56 (10), p.1392-1401

2013

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Daidzein alleviates neuronal damage and oxidative stress via GSK3β/Nrf2 pathway in mice

Journal of functional foods, 2022-05, Vol.92, p.105060, Article 105060

2022

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Chemical Structure Similarity Search for Ligand-based Virtual Screening: Methods and Computational Resources

Current drug targets, 2016-01, Vol.17 (14), p.1580-1585

2016

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Polo-box domain: a versatile mediator of polo-like kinase function

Cellular and molecular life sciences : CMLS, 2010-06, Vol.67 (12), p.1957-1970

2010

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Lycopene inhibits carrageenan-induced thrombi by regulating AKT/FoxO3a and TLR4/NF-κB pathways

Journal of functional foods, 2024-02, Vol.113, p.106021, Article 106021

2024

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Polysaccharide extracted from Morchella esculenta inhibits carrageenan-induced thrombosis in mice

Journal of functional foods, 2022-10, Vol.97, p.105235, Article 105235

2022

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Design, synthesis, and biological evaluation of novel highly selective polo-like kinase 2 inhibitors based on the tetrahydropteridin chemical scaffold

European journal of medicinal chemistry, 2018-01, Vol.143, p.724-731

2018

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LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress

Biomedicine & pharmacotherapy, 2020-03, Vol.123, p.109803-109803, Article 109803

2020

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Metalloprotein Inhibitors for the Treatment of Human Diseases

Current topics in medicinal chemistry, 2016-01, Vol.16 (4), p.384-396

2016

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LongShengZhi Capsule Attenuates Alzheimer-Like Pathology in APP/PS1 Double Transgenic Mice by Reducing Neuronal Oxidative Stress and Inflammation

Frontiers in aging neuroscience, 2020-11, Vol.12, p.582455-582455

2020

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Small-Molecule Kinase Inhibitors for the Treatment of Nononcologic Diseases

Comparison of Nine Programs Predicting pKa Values of Pharmaceutical Substances

Design, synthesis and anticancer activities of novel dual poly(ADP-ribose) polymerase-1/histone deacetylase-1 inhibitors

From monoclonal antibodies to small molecules: the development of inhibitors targeting the PD-1/PD-L1 pathway

Progress in the Discovery of Macrocyclic Histone Deacetylase Inhibitors for the Treatment of Cancer

A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo

Inhibitors of the anti-apoptotic Bcl-2 proteins: a patent review

Publisher Correction: Intestinal Nogo-B reduces GLP1 levels by binding to proglucagon on the endoplasmic reticulum to inhibit PCSK1 cleavage

Ascorbic acid enhances low-density lipoprotein receptor expression by suppressing proprotein convertase subtilisin/kexin 9 expression

Selective Histone Deacetylase Inhibitors with Anticancer Activity

Intestinal Nogo-B reduces GLP1 levels by binding to proglucagon on the endoplasmic reticulum to inhibit PCSK1 cleavage

Discovery and Development of Cyclin-Dependent Kinase 8 Inhibitors

Design, synthesis, and biological evaluation of 1, 3-disubstituted-pyrazole derivatives as new class I and IIb histone deacetylase inhibitors

NaoXinTong Capsule ameliorates memory deficit in APP/PS1 mice by regulating inflammatory cytokines

Glabridin Ameliorates Alcohol-Caused Liver Damage by Reducing Oxidative Stress and Inflammation via p38 MAPK/Nrf2/NF-κB Pathway

Diversity evolution and jump of Polo-like kinase 1 inhibitors

Daidzein alleviates neuronal damage and oxidative stress via GSK3β/Nrf2 pathway in mice

Chemical Structure Similarity Search for Ligand-based Virtual Screening: Methods and Computational Resources

Polo-box domain: a versatile mediator of polo-like kinase function

Lycopene inhibits carrageenan-induced thrombi by regulating AKT/FoxO3a and TLR4/NF-κB pathways

Polysaccharide extracted from Morchella esculenta inhibits carrageenan-induced thrombosis in mice

Design, synthesis, and biological evaluation of novel highly selective polo-like kinase 2 inhibitors based on the tetrahydropteridin chemical scaffold

LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress

Metalloprotein Inhibitors for the Treatment of Human Diseases

LongShengZhi Capsule Attenuates Alzheimer-Like Pathology in APP/PS1 Double Transgenic Mice by Reducing Neuronal Oxidative Stress and Inflammation

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