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Complexation and evolution of cis‐prenyltransferase homologues in Cinnamomum kanehirae deduced from kinetic and functional characterizations

Protein science, 2023-12, Vol.32 (12), p.e4828-n/a

2023

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Non‐Heme Iron Enzymes Catalyze Heterobicyclic and Spirocyclic Isoquinolone Core Formation in Piperazine Alkaloid Biosynthesis

Angewandte Chemie International Edition, 2024-05, Vol.63 (20), p.e202401324-n/a

International ed. in English, 2024

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Synthesis and evaluation of pyrazolone compounds as SARS-coronavirus 3C-like protease inhibitors

Bioorganic & medicinal chemistry, 2010-11, Vol.18 (22), p.7849-7854

2010

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Characterization of a Cis -Prenyltransferase from Lilium longiflorum Anther

Molecules (Basel, Switzerland), 2019-07, Vol.24 (15), p.2728

2019

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Biochemical Characterization and Structural Analysis of a Bifunctional Cellulase/Xylanase from Clostridium thermocellum

The Journal of biological chemistry, 2015-02, Vol.290 (9), p.5739-5748

2015

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Characterization and inhibition of SARS-coronavirus main protease

Current topics in medicinal chemistry, 2006-02, Vol.6 (4), p.361

Liang, Po-Huang

2006

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Small Molecules Targeting Severe Acute Respiratory Syndrome Human Coronavirus

Proceedings of the National Academy of Sciences - PNAS, 2004-07, Vol.101 (27), p.10012-10017

2004

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Chaperonin-Containing TCP-1 Promotes Cancer Chemoresistance and Metastasis through the AKT-GSK3β-β-Catenin and XIAP-Survivin Pathways

Cancers, 2020-12, Vol.12 (12), p.3865

2020

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Drug Repurposing for the Identification of Compounds with Anti-SARS-CoV-2 Capability via Multiple Targets

Pharmaceutics, 2022-01, Vol.14 (1), p.176

2022

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Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms

Proteins, structure, function, and bioinformatics, 2015-01, Vol.83 (1), p.37-45

2015

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Structure of a Heterotetrameric Geranyl Pyrophosphate Synthase from Mint (Mentha piperita) Reveals Intersubunit Regulation

The Plant cell, 2010-02, Vol.22 (2), p.454-467

2010

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Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds

The Journal of biological chemistry, 2009-03, Vol.284 (12), p.7646-7655

2009

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Structure and Inhibition of Tuberculosinol Synthase and Decaprenyl Diphosphate Synthase from Mycobacterium tuberculosis

Journal of the American Chemical Society, 2014-02, Vol.136 (7), p.2892-2896

2014

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Structures, mechanisms and inhibitors of undecaprenyl diphosphate synthase: A cis-prenyltransferase for bacterial peptidoglycan biosynthesis

Bioorganic chemistry, 2012-08, Vol.43, p.51-57

2012

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SARS‐CoV‐2 3CLpro displays faster self‐maturation in vitro than SARS‐CoV 3CLpro due to faster C‐terminal cleavage

FEBS letters, 2022-05, Vol.596 (9), p.1214-1224

2022

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Mechanism of the Maturation Process of SARS-CoV 3CL Protease[boxs]

The Journal of biological chemistry, 2005-09, Vol.280 (35), p.31257-31266

2005

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Traditional Chinese medicine herbal extracts of Cibotium barometz, Gentiana scabra, Dioscorea batatas, Cassia tora, and Taxillus chinensis inhibit SARS-CoV replication

Journal of Traditional and Complementary Medicine, 2011-10, Vol.1 (1), p.41-50

2011

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Reaction Kinetics, Catalytic Mechanisms, Conformational Changes, and Inhibitor Design for Prenyltransferases

Biochemistry (Easton), 2009-07, Vol.48 (28), p.6562-6570

Liang, Po-Huang

2009

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SARS-CoV-2 3CL pro displays faster self-maturation in vitro than SARS-CoV 3CL pro due to faster C-terminal cleavage

FEBS letters, 2022-05, Vol.596 (9), p.1214-1224

2022

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Characterization of SARS main protease and inhibitor assay using a fluorogenic substrate

Biochemical and biophysical research communications, 2004-06, Vol.318 (4), p.862-867

2004

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Systematic Studies on the Anti-SARS-CoV‑2 Mechanisms of Tea Polyphenol-Related Natural Products

ACS omega, 2024-06, Vol.9 (22), p.23984-23997

2024

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The catalytic roles of P185 and T188 and substrate-binding loop flexibility in 3α-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni

PloS one, 2013-05, Vol.8 (5), p.e63594-e63594

2013

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Conjugation of benzylvanillin and benzimidazole structure improves DNA binding with enhanced antileukemic properties

PloS one, 2013-11, Vol.8 (11), p.e80983

2013

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Identification, synthesis and evaluation of SARS-CoV and MERS-CoV 3C-like protease inhibitors

Bioorganic & medicinal chemistry, 2016-07, Vol.24 (13), p.3035-3042

2016

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Complexation and evolution of cis‐prenyltransferase homologues in Cinnamomum kanehirae deduced from kinetic and functional characterizations

Non‐Heme Iron Enzymes Catalyze Heterobicyclic and Spirocyclic Isoquinolone Core Formation in Piperazine Alkaloid Biosynthesis

Synthesis and evaluation of pyrazolone compounds as SARS-coronavirus 3C-like protease inhibitors

Characterization of a Cis -Prenyltransferase from Lilium longiflorum Anther

Biochemical Characterization and Structural Analysis of a Bifunctional Cellulase/Xylanase from Clostridium thermocellum

Characterization and inhibition of SARS-coronavirus main protease

Small Molecules Targeting Severe Acute Respiratory Syndrome Human Coronavirus

Chaperonin-Containing TCP-1 Promotes Cancer Chemoresistance and Metastasis through the AKT-GSK3β-β-Catenin and XIAP-Survivin Pathways

Simeprevir Potently Suppresses SARS-CoV‑2 Replication and Synergizes with Remdesivir

Drug Repurposing for the Identification of Compounds with Anti-SARS-CoV-2 Capability via Multiple Targets

Crystal structures of ligand-bound octaprenyl pyrophosphate synthase from Escherichia coli reveal the catalytic and chain-length determining mechanisms

Structure of a Heterotetrameric Geranyl Pyrophosphate Synthase from Mint (Mentha piperita) Reveals Intersubunit Regulation

Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds

Structure and Inhibition of Tuberculosinol Synthase and Decaprenyl Diphosphate Synthase from Mycobacterium tuberculosis

Structures, mechanisms and inhibitors of undecaprenyl diphosphate synthase: A cis-prenyltransferase for bacterial peptidoglycan biosynthesis

SARS‐CoV‐2 3CLpro displays faster self‐maturation in vitro than SARS‐CoV 3CLpro due to faster C‐terminal cleavage

Mechanism of the Maturation Process of SARS-CoV 3CL Protease[boxs]

Traditional Chinese medicine herbal extracts of Cibotium barometz, Gentiana scabra, Dioscorea batatas, Cassia tora, and Taxillus chinensis inhibit SARS-CoV replication

Reaction Kinetics, Catalytic Mechanisms, Conformational Changes, and Inhibitor Design for Prenyltransferases

SARS-CoV-2 3CL pro displays faster self-maturation in vitro than SARS-CoV 3CL pro due to faster C-terminal cleavage

Characterization of SARS main protease and inhibitor assay using a fluorogenic substrate

Systematic Studies on the Anti-SARS-CoV‑2 Mechanisms of Tea Polyphenol-Related Natural Products

The catalytic roles of P185 and T188 and substrate-binding loop flexibility in 3α-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni

Conjugation of benzylvanillin and benzimidazole structure improves DNA binding with enhanced antileukemic properties

Identification, synthesis and evaluation of SARS-CoV and MERS-CoV 3C-like protease inhibitors

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