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Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos

Science (American Association for the Advancement of Science), 2019-04, Vol.364 (6437), p.289-292

2019

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A Beloved Bioinformatician Buddy—In Memory of Professor Weimin Zhu

Genomics, proteomics & bioinformatics, 2022-12, Vol.20 (6), p.1037-1039

Li, Yixue

2022

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Mechanisms of drug combinations: interaction and network perspectives

Nature reviews. Drug discovery, 2009-02, Vol.8 (2), p.111-128

2009

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Hierarchical hollow MoS2 microspheres as materials for conductometric NO2 gas sensors

Sensors and actuators. B, Chemical, 2019-03, Vol.282, p.259-267

2019

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Single-cell RNA sequencing of peripheral blood mononuclear cells from acute Kawasaki disease patients

Nature communications, 2021-09, Vol.12 (1), p.5444-5444, Article 5444

2021

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A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects

Nature methods, 2020-06, Vol.17 (6), p.600-604

2020

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Optimization of C-to-G base editors with sequence context preference predictable by machine learning methods

Nature communications, 2021-08, Vol.12 (1), p.4902-4902, Article 4902

2021

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Big Biological Data: Challenges and Opportunities

Genomics, proteomics & bioinformatics, 2014-10, Vol.12 (5), p.187-189

2014

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Using Machine Learning Methods to Study Colorectal Cancer Tumor Micro-Environment and Its Biomarkers

International journal of molecular sciences, 2023-07, Vol.24 (13), p.11133

2023

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Current progress, challenges, and future perspectives of language models for protein representation and protein design

Innovation (New York, NY), 2023-07, Vol.4 (4), p.100446-100446, Article 100446

2023

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Land-Use Optimization Based on Ecological Security Pattern—A Case Study of Baicheng, Northeast China

Remote sensing (Basel, Switzerland), 2023-12, Vol.15 (24), p.5671

2023

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Regulation of Cellular Metabolism by Protein Lysine Acetylation

Science (American Association for the Advancement of Science), 2010-02, Vol.327 (5968), p.1000-1004

2010

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CRISPR/Cas9-mediated targeted chromosome elimination

Genome Biology, 2017-11, Vol.18 (1), p.224-18, Article 224

2017

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Association between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral resistance

The Lancet (British edition), 2013-06, Vol.381 (9885), p.2273-2279

2013

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Predicting protein-protein interactions based only on sequences information

Proceedings of the National Academy of Sciences - PNAS, 2007-03, Vol.104 (11), p.4337-4341

2007

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Integrated genomic and transcriptomic analysis reveals unique characteristics of hepatic metastases and pro-metastatic role of complement C1q in pancreatic ductal adenocarcinoma

Genome Biology, 2021-01, Vol.22 (1), p.4-4, Article 4

2021

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Whole-genome sequencing of six dog breeds from continuous altitudes reveals adaptation to high-altitude hypoxia

Genome research, 2014-08, Vol.24 (8), p.1308-1315

2014

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Berberine ameliorates nonalcoholic fatty liver disease by a global modulation of hepatic mRNA and lncRNA expression profiles

Journal of translational medicine, 2015-01, Vol.13 (1), p.24-24, Article 24

2015

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TMO-Net: an explainable pretrained multi-omics model for multi-task learning in oncology

Genome Biology, 2024-06, Vol.25 (1), p.149-24

2024

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More than 9,000,000 unique genes in human gut bacterial community: estimating gene numbers inside a human body

PloS one, 2009-06, Vol.4 (6), p.e6074-e6074

2009

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Adaptive evolution of proteins in hepatitis B virus during divergence of genotypes

Scientific reports, 2017-05, Vol.7 (1), p.1990-11, Article 1990

2017

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Deep Learning of radiology-genomics integration for computational oncology: A mini review

Computational and structural biotechnology journal, 2024-12, Vol.23, p.2708-2716

2024

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Integrative analysis of DNA methylation and gene expression reveals hepatocellular carcinoma-specific diagnostic biomarkers

Genome medicine, 2018-05, Vol.10 (1), p.42-42, Article 42

2018

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GOTI, a method to identify genome-wide off-target effects of genome editing in mouse embryos

Nature protocols, 2020-09, Vol.15 (9), p.3009-3029

2020

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LAceP: lysine acetylation site prediction using logistic regression classifiers

PloS one, 2014-02, Vol.9 (2), p.e89575-e89575

2014

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Cytosine base editor generates substantial off-target single-nucleotide variants in mouse embryos

A Beloved Bioinformatician Buddy—In Memory of Professor Weimin Zhu

Mechanisms of drug combinations: interaction and network perspectives

Hierarchical hollow MoS2 microspheres as materials for conductometric NO2 gas sensors

Single-cell RNA sequencing of peripheral blood mononuclear cells from acute Kawasaki disease patients

A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects

Optimization of C-to-G base editors with sequence context preference predictable by machine learning methods

Big Biological Data: Challenges and Opportunities

Using Machine Learning Methods to Study Colorectal Cancer Tumor Micro-Environment and Its Biomarkers

Current progress, challenges, and future perspectives of language models for protein representation and protein design

Land-Use Optimization Based on Ecological Security Pattern—A Case Study of Baicheng, Northeast China

Regulation of Cellular Metabolism by Protein Lysine Acetylation

CRISPR/Cas9-mediated targeted chromosome elimination

Association between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral resistance

Predicting protein-protein interactions based only on sequences information

Integrated genomic and transcriptomic analysis reveals unique characteristics of hepatic metastases and pro-metastatic role of complement C1q in pancreatic ductal adenocarcinoma

Whole-genome sequencing of six dog breeds from continuous altitudes reveals adaptation to high-altitude hypoxia

Berberine ameliorates nonalcoholic fatty liver disease by a global modulation of hepatic mRNA and lncRNA expression profiles

TMO-Net: an explainable pretrained multi-omics model for multi-task learning in oncology

More than 9,000,000 unique genes in human gut bacterial community: estimating gene numbers inside a human body

Adaptive evolution of proteins in hepatitis B virus during divergence of genotypes

Deep Learning of radiology-genomics integration for computational oncology: A mini review

Integrative analysis of DNA methylation and gene expression reveals hepatocellular carcinoma-specific diagnostic biomarkers

GOTI, a method to identify genome-wide off-target effects of genome editing in mouse embryos

LAceP: lysine acetylation site prediction using logistic regression classifiers

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