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Bile Acid Metabolism and Signaling in Cholestasis, Inflammation, and Cancer

Advances in pharmacology (1990), 2015, Vol.74, p.263-302

2015

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Bile acid signaling in metabolic disease and drug therapy

Pharmacological reviews, 2014-10, Vol.66 (4), p.948-983

2014

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Pharmacology of bile acid receptors: Evolution of bile acids from simple detergents to complex signaling molecules

Pharmacological research, 2016-02, Vol.104, p.9-21

2016

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Impaired TFEB-Mediated Lysosome Biogenesis and Autophagy Promote Chronic Ethanol-Induced Liver Injury and Steatosis in Mice

Gastroenterology (New York, N.Y. 1943), 2018-09, Vol.155 (3), p.865-879.e12

2018

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Prenatal Diagnosis of Pulmonary Artery Sling With HD Live-Flow Render Mode and Spatiotemporal Image Correlation (STIC)

Circulation Journal, 2022/10/25, Vol.86(11), pp.1787

2022

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Prenatal Diagnosis of Fetal Retroesophageal Left Brachiocephalic Vein With HDlive-Flow Render Mode and Spatiotemporal Image Correlation

Circulation Journal, 2020/12/25, Vol.85(1), pp.80

2020

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Current advances in ultrasound-combined nanobubbles for cancer-targeted therapy: a review of the current status and future perspectives

RSC advances, 2021-03, Vol.11 (21), p.12915-12928

2021

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An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis

Nature communications, 2020-07, Vol.11 (1), p.3612-16, Article 3612

2020

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Bile acid signaling in lipid metabolism: Metabolomic and lipidomic analysis of lipid and bile acid markers linked to anti-obesity and anti-diabetes in mice

Biochimica et biophysica acta, 2015-01, Vol.1851 (1), p.19-29

2015

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Hepatocyte sortilin 1 knockout and treatment with a sortilin 1 inhibitor reduced plasma cholesterol in Western diet-fed mice

Journal of lipid research, 2019-03, Vol.60 (3), p.539-549

2019

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Loss of hepatic DRP1 exacerbates alcoholic hepatitis by inducing megamitochondria and mitochondrial maladaptation

Hepatology (Baltimore, Md.), 2023-01, Vol.77 (1), p.159-175

2023

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Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK3)–Mixed Lineage Kinase Domain-Like Protein (MLKL)–Mediated Necroptosis Contributes to Ischemia-Reperfusion Injury of Steatotic Livers

The American journal of pathology, 2019-07, Vol.189 (7), p.1363-1374

2019

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Transgenic expression of cholesterol 7α‐hydroxylase in the liver prevents high‐fat diet–induced obesity and insulin resistance in mice

Hepatology (Baltimore, Md.), 2010-08, Vol.52 (2), p.678-690

2010

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Combining ASBT inhibitor and FGF15 treatments enhances therapeutic efficacy against cholangiopathy in female but not male Cyp2c70 KO mice

Journal of lipid research, 2023-03, Vol.64 (3), p.100340-100340, Article 100340

2023

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Using Nobel Prize case-based learning in Medical Immunology to cultivate critical thinking dispositions for medical undergraduates

BMC medical education, 2024-10, Vol.24 (1), p.1213-10, Article 1213

2024

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Gly-β-MCA is a potent anti-cholestasis agent against “human-like” hydrophobic bile acid-induced biliary injury in mice

Journal of lipid research, 2024-10, Vol.65 (10), p.100649, Article 100649

2024

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Hepatic Autophagy Deficiency Compromises Farnesoid X Receptor Functionality and Causes Cholestatic Injury

Hepatology (Baltimore, Md.), 2019-05, Vol.69 (5), p.2196-2213

2019

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Overexpression of cholesterol 7α‐hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis

Hepatology (Baltimore, Md.), 2011-03, Vol.53 (3), p.996-1006

2011

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Bile acids regulation of cellular stress responses in liver physiology and diseases

eGastroenterology, 2024-04, Vol.2 (2), p.e100074

2024

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TFEB regulates sulfur amino acid and coenzyme A metabolism to support hepatic metabolic adaptation and redox homeostasis

Nature communications, 2022-09, Vol.13 (1), p.5696-15, Article 5696

2022

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Liver-specific microRNA-185 knockout promotes cholesterol dysregulation in mice

Liver research, 2021-12, Vol.5 (4), p.232-238

2021

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Pathogenesis of fatty liver diseases and hepatocellular carcinoma

Liver research, 2022-12, Vol.6 (4), p.201-202

2022

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Saturated fatty acids activate ERK signaling to downregulate hepatic sortilin 1 in obese and diabetic mice[S]

Journal of lipid research, 2013-10, Vol.54 (10), p.2754-2762

2013

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All‐trans‐retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade

Hepatology (Baltimore, Md.), 2014-05, Vol.59 (5), p.1750-1760

2014

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Sodium Tanshinone IIA Sulfonate Protects Primary Cardiomyocytes Against Radiation-Induced Myocardial Injury via the p38 Pathway

International Heart Journal, 2024/07/31, Vol.65(4), pp.730-737

2024

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Bile Acid Metabolism and Signaling in Cholestasis, Inflammation, and Cancer

Bile acid signaling in metabolic disease and drug therapy

Pharmacology of bile acid receptors: Evolution of bile acids from simple detergents to complex signaling molecules

Impaired TFEB-Mediated Lysosome Biogenesis and Autophagy Promote Chronic Ethanol-Induced Liver Injury and Steatosis in Mice

Prenatal Diagnosis of Pulmonary Artery Sling With HD Live-Flow Render Mode and Spatiotemporal Image Correlation (STIC)

Prenatal Diagnosis of Fetal Retroesophageal Left Brachiocephalic Vein With HDlive-Flow Render Mode and Spatiotemporal Image Correlation

Current advances in ultrasound-combined nanobubbles for cancer-targeted therapy: a review of the current status and future perspectives

An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis

Bile acid signaling in lipid metabolism: Metabolomic and lipidomic analysis of lipid and bile acid markers linked to anti-obesity and anti-diabetes in mice

Hepatocyte sortilin 1 knockout and treatment with a sortilin 1 inhibitor reduced plasma cholesterol in Western diet-fed mice

Loss of hepatic DRP1 exacerbates alcoholic hepatitis by inducing megamitochondria and mitochondrial maladaptation

Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK3)–Mixed Lineage Kinase Domain-Like Protein (MLKL)–Mediated Necroptosis Contributes to Ischemia-Reperfusion Injury of Steatotic Livers

Transgenic expression of cholesterol 7α‐hydroxylase in the liver prevents high‐fat diet–induced obesity and insulin resistance in mice

Combining ASBT inhibitor and FGF15 treatments enhances therapeutic efficacy against cholangiopathy in female but not male Cyp2c70 KO mice

Using Nobel Prize case-based learning in Medical Immunology to cultivate critical thinking dispositions for medical undergraduates

Gly-β-MCA is a potent anti-cholestasis agent against “human-like” hydrophobic bile acid-induced biliary injury in mice

Hepatic Autophagy Deficiency Compromises Farnesoid X Receptor Functionality and Causes Cholestatic Injury

Overexpression of cholesterol 7α‐hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis

Bile acids regulation of cellular stress responses in liver physiology and diseases

TFEB regulates sulfur amino acid and coenzyme A metabolism to support hepatic metabolic adaptation and redox homeostasis

Liver-specific microRNA-185 knockout promotes cholesterol dysregulation in mice

Pathogenesis of fatty liver diseases and hepatocellular carcinoma

Saturated fatty acids activate ERK signaling to downregulate hepatic sortilin 1 in obese and diabetic mice[S]

All‐trans‐retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade

Sodium Tanshinone IIA Sulfonate Protects Primary Cardiomyocytes Against Radiation-Induced Myocardial Injury via the p38 Pathway

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