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Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism

Science (American Association for the Advancement of Science), 2016-02, Vol.351 (6273), p.604-608

2016

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Development of combination therapies to maximize the impact of KRAS-G12C inhibitors in lung cancer

Science translational medicine, 2019-09, Vol.11 (510)

2019

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Sugar and acid concentrations in 98 grape cultivars analyzed by principal component analysis

Journal of the science of food and agriculture, 2006-08, Vol.86 (10), p.1526-1536

2006

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Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor

Cell, 2018-01, Vol.172 (3), p.578-589.e17

2018

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Research on Reliability for Servo Turret Based on Vibration Transmission Path System with Stiffness Degradation Model

Mathematical problems in engineering, 2020, Vol.2020 (2020), p.1-11

2020

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Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State

Cancer discovery, 2016-03, Vol.6 (3), p.316-329

2016

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KRAS G12C NSCLC Models Are Sensitive to Direct Targeting of KRAS in Combination with PI3K Inhibition

Clinical cancer research, 2019-01, Vol.25 (2), p.796-807

2019

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Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia

The Journal of clinical investigation, 2020-02, Vol.130 (2), p.981-997

2020

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Selective Metalation of Functionalized Quinazolines to Enable Discovery and Advancement of Covalent KRAS Inhibitors

Organic process research & development, 2022-10, Vol.26 (10), p.2926-2936

2022

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Synthesis of the next-generation therapeutic antibodies that combine cell targeting and antibody-catalyzed prodrug activation

Proceedings of the National Academy of Sciences - PNAS, 2007-03, Vol.104 (13), p.5584-5589

2007

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Factors associated with reverse change of serum ALT activity in patients with chronic hepatitis B

World Chinese Journal of Digestology, 2018-12, Vol.26 (34), p.1996-2001

2018

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Selective Inhibition of Phosphoinositide 3-Kinase p110α Preserves Lymphocyte Function

The Journal of biological chemistry, 2013-02, Vol.288 (8), p.5718-5731

2013

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Changes in shear properties of granite fractures subjected to cyclic heating and air-cooling treatments

Journal of Rock Mechanics and Geotechnical Engineering, 2024-04

2024

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Development and in-orbit performance evaluation of multi-layered nested grazing incidence optics

Wuli xuebao, 2020-02, Vol.69 (3), p.30702

2020

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The reactivity-driven biochemical mechanism of covalent KRASG12C inhibitors

Nature structural & molecular biology, 2018-06, Vol.25 (6), p.454-462

2018

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Regioselective Functionalization of 4‑Methyl‑1H‑indole for Scalable Synthesis of 2‑Cyano-5-formyl-4-methyl‑1H‑indole

Organic process research & development, 2018-01, Vol.22 (1), p.97-102

2018

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Prodrugs of Dynemicin Analogs for Selective Chemotherapy Mediated by an Aldolase Catalytic Ab

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (9), p.3095-3099

2004

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Recent Progress in Syntheses of Higher 3-Deoxy-2-ulosonic Acids and Their Derivatives

Current organic chemistry, 2003-03, Vol.7 (5), p.447-475

2003

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Phenoxymethylpenicillin-intercalated hydrotalcite as a bacteria inhibitor

Journal of chemical technology and biotechnology (1986), 2006-01, Vol.81 (1), p.89-93

2006

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Feedback recurrent neural network-based embedded vector and its application in topic model

EURASIP Journal on Embedded Systems, 2016-07, Vol.2017 (1), p.1, Article 5

2016

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Phosphorylation of Nonmuscle Myosin Light Chain Promotes Endothelial Injury in Hyperlipidemic Rats Through a Mechanism Involving Downregulation of Dimethylarginine Dimethylaminohydrolase 2

Journal of cardiovascular pharmacology and therapeutics, 2016-11, Vol.21 (6), p.536-548

2016

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Studies toward the duocarmycin prodrugs for the antibody prodrug therapy approach

Tetrahedron letters, 2009-06, Vol.50 (24), p.2932-2935

2009

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Discovery of tricyclic 5,6-dihydro-1H-pyridin-2-ones as novel, potent, and orally bioavailable inhibitors of HCV NS5B polymerase

Bioorganic & medicinal chemistry letters, 2009-11, Vol.19 (22), p.6404-6412

2009

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Asymmetric epoxidation of alkenes catalysed by chromium binaphthyl Schiff base complex supported on MCM-41

Chemical communications (Cambridge, England), 1999-09 (18), p.1789-1790

1999

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Aldolase Antibody Activation of Prodrugs of Potent Aldehyde-Containing Cytotoxics for Selective Chemotherapy

Chemistry : a European journal, 2004-10, Vol.10 (21), p.5467-5472

2004

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Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism

Development of combination therapies to maximize the impact of KRAS-G12C inhibitors in lung cancer

Sugar and acid concentrations in 98 grape cultivars analyzed by principal component analysis

Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor

Research on Reliability for Servo Turret Based on Vibration Transmission Path System with Stiffness Degradation Model

Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State

KRAS G12C NSCLC Models Are Sensitive to Direct Targeting of KRAS in Combination with PI3K Inhibition

Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia

Selective Metalation of Functionalized Quinazolines to Enable Discovery and Advancement of Covalent KRAS Inhibitors

Synthesis of the next-generation therapeutic antibodies that combine cell targeting and antibody-catalyzed prodrug activation

Factors associated with reverse change of serum ALT activity in patients with chronic hepatitis B

Selective Inhibition of Phosphoinositide 3-Kinase p110α Preserves Lymphocyte Function

Changes in shear properties of granite fractures subjected to cyclic heating and air-cooling treatments

Development and in-orbit performance evaluation of multi-layered nested grazing incidence optics

The reactivity-driven biochemical mechanism of covalent KRASG12C inhibitors

Regioselective Functionalization of 4‑Methyl‑1H‑indole for Scalable Synthesis of 2‑Cyano-5-formyl-4-methyl‑1H‑indole

Prodrugs of Dynemicin Analogs for Selective Chemotherapy Mediated by an Aldolase Catalytic Ab

Recent Progress in Syntheses of Higher 3-Deoxy-2-ulosonic Acids and Their Derivatives

Phenoxymethylpenicillin-intercalated hydrotalcite as a bacteria inhibitor

Feedback recurrent neural network-based embedded vector and its application in topic model

Phosphorylation of Nonmuscle Myosin Light Chain Promotes Endothelial Injury in Hyperlipidemic Rats Through a Mechanism Involving Downregulation of Dimethylarginine Dimethylaminohydrolase 2

Studies toward the duocarmycin prodrugs for the antibody prodrug therapy approach

Discovery of tricyclic 5,6-dihydro-1H-pyridin-2-ones as novel, potent, and orally bioavailable inhibitors of HCV NS5B polymerase

Asymmetric epoxidation of alkenes catalysed by chromium binaphthyl Schiff base complex supported on MCM-41

Aldolase Antibody Activation of Prodrugs of Potent Aldehyde-Containing Cytotoxics for Selective Chemotherapy

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