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Cholesterol Transport through Lysosome-Peroxisome Membrane Contacts

Cell, 2015-04, Vol.161 (2), p.291-306

2015

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Inhibition of the sterol regulatory element‐binding protein pathway suppresses hepatocellular carcinoma by repressing inflammation in mice

Hepatology (Baltimore, Md.), 2017-06, Vol.65 (6), p.1936-1947

2017

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Inhibition of SREBP by a Small Molecule, Betulin, Improves Hyperlipidemia and Insulin Resistance and Reduces Atherosclerotic Plaques

Cell metabolism, 2011-01, Vol.13 (1), p.44-56

2011

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Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling

Molecular cell, 2017-04, Vol.66 (1), p.154-162.e10

2017

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Acyl-coenzyme A:cholesterol acyltransferases

American journal of physiology: endocrinology and metabolism, 2009-07, Vol.297 (1), p.E1-E9

2009

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A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption

Science (American Association for the Advancement of Science), 2018-06, Vol.360 (6393), p.1087-1092

2018

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Characterization of Volatile Organic Compounds Emitted from Endophytic Burkholderia cenocepacia ETR-B22 by SPME-GC-MS and Their Inhibitory Activity against Various Plant Fungal Pathogens

Molecules (Basel, Switzerland), 2020-08, Vol.25 (17), p.3765

2020

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Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation

Nature cell biology, 2017-07, Vol.19 (7), p.808

2017

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AAV9-NPC1 significantly ameliorates Purkinje cell death and behavioral abnormalities in mouse NPC disease

Journal of lipid research, 2017-03, Vol.58 (3), p.512-518

2017

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Genome editing with CRISPR/Cas9 in postnatal mice corrects PRKAG2 cardiac syndrome

Cell research, 2016-10, Vol.26 (10), p.1099-1111

2016

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Myeloid Acat1/Soat1 KO attenuates pro-inflammatory responses in macrophages and protects against atherosclerosis in a model of advanced lesions

The Journal of biological chemistry, 2019-10, Vol.294 (43), p.15836-15849

2019

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The Cholesterol Absorption Inhibitor Ezetimibe Acts by Blocking the Sterol-Induced Internalization of NPC1L1

Cell metabolism, 2008-06, Vol.7 (6), p.508-519

2008

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Novel Substituted Thiophenes and Sulf-Polyacetylene Ester from Echinops ritro L

Molecules (Basel, Switzerland), 2019-02, Vol.24 (4), p.805

2019

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Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake

Proceedings of the National Academy of Sciences - PNAS, 2011-01, Vol.108 (2), p.551-556

2011

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The N-terminal Domain of NPC1L1 Protein Binds Cholesterol and Plays Essential Roles in Cholesterol Uptake

The Journal of biological chemistry, 2011-07, Vol.286 (28), p.25088-25097

2011

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Molecular Characterization of the NPC1L1 Variants Identified from Cholesterol Low Absorbers

The Journal of biological chemistry, 2011-03, Vol.286 (9), p.7397-7408

2011

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Ezetimibe blocks the internalization of NPC1L1 and cholesterol in mouse small intestine

Journal of lipid research, 2012-10, Vol.53 (10), p.2092-2101

2012

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Anterior wall adenocarcinoma of bladder with similar clinicopathological and prognostic characteristics as common bladder carcinomas should not be treated as or classified into urachal adenocarcinomas

Cancer medicine (Malden, MA), 2021-08, Vol.10 (16), p.5415-5428

2021

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The GARP Complex Is Involved in Intracellular Cholesterol Transport via Targeting NPC2 to Lysosomes

Cell reports (Cambridge), 2017-06, Vol.19 (13), p.2823-2835

2017

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Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism

Nature (London), 2016-03, Vol.531 (7596), p.651-655

2016

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Design and synthesis of simple, yet potent and selective non-ring-A pyripyropene A-based inhibitors of acyl-coenzyme A: cholesterol acyltransferase 2 (ACAT2)

Organic & biomolecular chemistry, 2016-01, Vol.14 (2), p.747-751

2016

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Membrane topology of human NPC1L1, a key protein in enterohepatic cholesterol absorption

Journal of lipid research, 2009-08, Vol.50 (8), p.1653-1662

2009

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Gpnmb secreted from liver promotes lipogenesis in white adipose tissue and aggravates obesity and insulin resistance

Nature metabolism, 2019-05, Vol.1 (5), p.570-583

2019

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Forward genetic screening for regulators involved in cholesterol synthesis using validation-based insertional mutagenesis

PloS one, 2014-11, Vol.9 (11), p.e112632

2014

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Acyl-CoA:cholesterol acyltransferases (ACATs/SOATs): Enzymes with multiple sterols as substrates and as activators

The Journal of steroid biochemistry and molecular biology, 2015-07, Vol.151, p.102-107

2015

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Cholesterol Transport through Lysosome-Peroxisome Membrane Contacts

Inhibition of the sterol regulatory element‐binding protein pathway suppresses hepatocellular carcinoma by repressing inflammation in mice

Inhibition of SREBP by a Small Molecule, Betulin, Improves Hyperlipidemia and Insulin Resistance and Reduces Atherosclerotic Plaques

Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling

Acyl-coenzyme A:cholesterol acyltransferases

A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption

Characterization of Volatile Organic Compounds Emitted from Endophytic Burkholderia cenocepacia ETR-B22 by SPME-GC-MS and Their Inhibitory Activity against Various Plant Fungal Pathogens

Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation

AAV9-NPC1 significantly ameliorates Purkinje cell death and behavioral abnormalities in mouse NPC disease

Genome editing with CRISPR/Cas9 in postnatal mice corrects PRKAG2 cardiac syndrome

Myeloid Acat1/Soat1 KO attenuates pro-inflammatory responses in macrophages and protects against atherosclerosis in a model of advanced lesions

The Cholesterol Absorption Inhibitor Ezetimibe Acts by Blocking the Sterol-Induced Internalization of NPC1L1

Novel Substituted Thiophenes and Sulf-Polyacetylene Ester from Echinops ritro L

Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake

The N-terminal Domain of NPC1L1 Protein Binds Cholesterol and Plays Essential Roles in Cholesterol Uptake

Molecular Characterization of the NPC1L1 Variants Identified from Cholesterol Low Absorbers

Ezetimibe blocks the internalization of NPC1L1 and cholesterol in mouse small intestine

Anterior wall adenocarcinoma of bladder with similar clinicopathological and prognostic characteristics as common bladder carcinomas should not be treated as or classified into urachal adenocarcinomas

The GARP Complex Is Involved in Intracellular Cholesterol Transport via Targeting NPC2 to Lysosomes

Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism

Design and synthesis of simple, yet potent and selective non-ring-A pyripyropene A-based inhibitors of acyl-coenzyme A: cholesterol acyltransferase 2 (ACAT2)

Membrane topology of human NPC1L1, a key protein in enterohepatic cholesterol absorption

Gpnmb secreted from liver promotes lipogenesis in white adipose tissue and aggravates obesity and insulin resistance

Forward genetic screening for regulators involved in cholesterol synthesis using validation-based insertional mutagenesis

Acyl-CoA:cholesterol acyltransferases (ACATs/SOATs): Enzymes with multiple sterols as substrates and as activators

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