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Efficient enzymatic synthesis of (S)-1-(3′-bromo-2′-methoxyphenyl)ethanol, the key building block of lusutrombopag

Green synthesis and catalysis, 2023-08, Vol.4 (3), p.268-271

2023

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Asymmetric Synthesis of Both Enantiomers of Dimethyl 2-Methylsuccinate by the Ene-Reductase-Catalyzed Reduction at High Substrate Concentration

Catalysts, 2022-10, Vol.12 (10), p.1133

2022

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Regulatory Network Analysis of Mutated Genes Based on Multi-Omics Data Reveals the Exclusive Features in Tumor Immune Microenvironment Between Left-Sided and Right-Sided Colon Cancer

Frontiers in oncology, 2021-06, Vol.11, p.685515-685515

2021

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Chemo-Enzymatic Strategy for the Efficient Synthesis of Steroidal Drugs with 10α-Methyl Group and a Side Chain at C17-Position from Biorenewable Phytosterols

JACS Au, 2024-04, Vol.4 (4), p.1356-1364

2024

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Microbial stereospecific reduction of 3-quinuclidinone with newly isolated Nocardia sp. and Rhodococcus erythropolis

Journal of molecular catalysis. B, Enzymatic, 2013-04, Vol.88, p.14-19

2013

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Asymmetric Synthesis of Fused-Ring Tetrahydroisoquinolines and Tetrahydro-β-carbolines from 2‑Arylethylamines via a Chemoenzymatic Approach

Organic letters, 2022-09, Vol.24 (36), p.6531-6536

2022

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Biocatalytic Access to 1,4-Diazepanes via Imine Reductase-Catalyzed Intramolecular Asymmetric Reductive Amination

ACS catalysis, 2020-08, Vol.10 (15), p.8780-8787

2020

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Inverting the Enantiopreference of Nitrilase‐Catalyzed Desymmetric Hydrolysis of Prochiral Dinitriles by Reshaping the Binding Pocket with a Mirror‐Image Strategy

Angewandte Chemie International Edition, 2021-02, Vol.60 (7), p.3679-3684

International ed. in English, 2021

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Simultaneous Preparation of (S)‑2-Aminobutane and d‑Alanine or d‑Homoalanine via Biocatalytic Transamination at High Substrate Concentration

Organic process research & development, 2022-07, Vol.26 (7), p.2013-2020

2022

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The global, regional, and national burden of colorectal cancer in 204 countries and territories from 1990 to 2019

Journal of public health, 2024-04, Vol.32 (4), p.609-618

2024

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Crystal Structures and Catalytic Mechanism of l‐erythro‐3,5‐Diaminohexanoate Dehydrogenase and Rational Engineering for Asymmetric Synthesis of β‐Amino Acids

Angewandte Chemie International Edition, 2021-04, Vol.60 (18), p.10203-10210

International ed. in English, 2021

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Correction to: The global, regional, and national burden of colorectal cancer in 204 countries and territories from 1990 to 2019

Journal of public health, 2024-04, Vol.32 (4), p.619-619

2024

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Highly Diastereoselective Synthesis of 2,2-Disubstituted Cyclopentane-1,3-diols via Stepwise Ketone Reduction Enabling Concise Chirality Construction

Journal of organic chemistry, 2020-08, Vol.85 (15), p.9599-9606

2020

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Telomere in colorectal cancer associated with distant metastases and predicted a poor prognosis

Translational cancer research, 2021-06, Vol.10 (6), p.2906-2917

2021

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Prognostic signatures and potential pathogenesis of eRNAs‐related genes in colon adenocarcinoma

Molecular carcinogenesis, 2022-01, Vol.61 (1), p.59-72

2022

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Biocatalytic production of (S)-1,2,4-butanetriol from d-xylose by whole cells of engineered Escherichia coli

Molecular catalysis, 2024-06, Vol.562, p.114230, Article 114230

2024

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Enzymatic synthesis of d-alanine from a renewable starting material by co-immobilized dehydrogenases

Process biochemistry (1991), 2018-03, Vol.66, p.126-132

2018

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Protective Effects of Curcumin on Colon Cancer Based on Regulation of lncRNA NBR2 Targeting Notch1 for Epithelial-mesenchymal Transition

International journal of human genetics, 2023-10, Vol.23 (4), p.232

2023

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The function of steroid terminal monooxygenase in cholesterol or phytosterol degradation by the Mycobacterium neoaurum NRRL B-3805

Systems Microbiology and Biomanufacturing, 2023-10, Vol.3 (4), p.585-592

2023

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Fruquintinib for refractory colorectal cancer in a pre-treated 82-year-old patient achieved a progression-free survival of 25 months: a case report

Journal of gastrointestinal oncology, 2022-10, Vol.13 (5), p.2667-2671

2022

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PP248 Efficacy and safety of fruquintnib plus biweekly TAS-102 and stereotactic body radiotherapy（SBRT） for metastatic colorectal cancer: A multicenter phase II trial

ESMO open, 2023-12, Vol.8 (1), p.102172, Article 102172

2023

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Enzymatic synthesis of 3-hydroxypropionic acid at high productivity by using free or immobilized cells of recombinant Escherichia coli

Journal of molecular catalysis. B, Enzymatic, 2016-07, Vol.129, p.37-42

2016

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Enzymatic Synthesis of a Key Intermediate for Rosuvastatin by Nitrilase-Catalyzed Hydrolysis of Ethyl (R)-4-Cyano-3-hydroxybutyate at High Substrate Concentration

ChemCatChem, 2015-01, Vol.7 (2), p.271-275

2015

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Fruquintinib in metastatic colorectal cancer: a multicenter real-world analysis on efficacy, safety, and predictive and prognostic factors

Journal of gastrointestinal oncology, 2024-08, Vol.15 (4), p.1519-1533

2024

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Inverting the Enantiopreference of Nitrilase‐Catalyzed Desymmetric Hydrolysis of Prochiral Dinitriles by Reshaping the Binding Pocket with a Mirror‐Image Strategy

Angewandte Chemie, 2021-02, Vol.133 (7), p.3723-3728

2021

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Efficient enzymatic synthesis of (S)-1-(3′-bromo-2′-methoxyphenyl)ethanol, the key building block of lusutrombopag

Asymmetric Synthesis of Both Enantiomers of Dimethyl 2-Methylsuccinate by the Ene-Reductase-Catalyzed Reduction at High Substrate Concentration

Regulatory Network Analysis of Mutated Genes Based on Multi-Omics Data Reveals the Exclusive Features in Tumor Immune Microenvironment Between Left-Sided and Right-Sided Colon Cancer

Chemo-Enzymatic Strategy for the Efficient Synthesis of Steroidal Drugs with 10α-Methyl Group and a Side Chain at C17-Position from Biorenewable Phytosterols

Microbial stereospecific reduction of 3-quinuclidinone with newly isolated Nocardia sp. and Rhodococcus erythropolis

Asymmetric Synthesis of Fused-Ring Tetrahydroisoquinolines and Tetrahydro-β-carbolines from 2‑Arylethylamines via a Chemoenzymatic Approach

Biocatalytic Access to 1,4-Diazepanes via Imine Reductase-Catalyzed Intramolecular Asymmetric Reductive Amination

Inverting the Enantiopreference of Nitrilase‐Catalyzed Desymmetric Hydrolysis of Prochiral Dinitriles by Reshaping the Binding Pocket with a Mirror‐Image Strategy

Simultaneous Preparation of (S)‑2-Aminobutane and d‑Alanine or d‑Homoalanine via Biocatalytic Transamination at High Substrate Concentration

The global, regional, and national burden of colorectal cancer in 204 countries and territories from 1990 to 2019

Crystal Structures and Catalytic Mechanism of l‐erythro‐3,5‐Diaminohexanoate Dehydrogenase and Rational Engineering for Asymmetric Synthesis of β‐Amino Acids

Correction to: The global, regional, and national burden of colorectal cancer in 204 countries and territories from 1990 to 2019

Highly Diastereoselective Synthesis of 2,2-Disubstituted Cyclopentane-1,3-diols via Stepwise Ketone Reduction Enabling Concise Chirality Construction

Telomere in colorectal cancer associated with distant metastases and predicted a poor prognosis

Prognostic signatures and potential pathogenesis of eRNAs‐related genes in colon adenocarcinoma

Biocatalytic production of (S)-1,2,4-butanetriol from d-xylose by whole cells of engineered Escherichia coli

Enzymatic synthesis of d-alanine from a renewable starting material by co-immobilized dehydrogenases

Protective Effects of Curcumin on Colon Cancer Based on Regulation of lncRNA NBR2 Targeting Notch1 for Epithelial-mesenchymal Transition

The function of steroid terminal monooxygenase in cholesterol or phytosterol degradation by the Mycobacterium neoaurum NRRL B-3805

Fruquintinib for refractory colorectal cancer in a pre-treated 82-year-old patient achieved a progression-free survival of 25 months: a case report

PP248 Efficacy and safety of fruquintnib plus biweekly TAS-102 and stereotactic body radiotherapy（SBRT） for metastatic colorectal cancer: A multicenter phase II trial

Enzymatic synthesis of 3-hydroxypropionic acid at high productivity by using free or immobilized cells of recombinant Escherichia coli

Enzymatic Synthesis of a Key Intermediate for Rosuvastatin by Nitrilase-Catalyzed Hydrolysis of Ethyl (R)-4-Cyano-3-hydroxybutyate at High Substrate Concentration

Fruquintinib in metastatic colorectal cancer: a multicenter real-world analysis on efficacy, safety, and predictive and prognostic factors

Inverting the Enantiopreference of Nitrilase‐Catalyzed Desymmetric Hydrolysis of Prochiral Dinitriles by Reshaping the Binding Pocket with a Mirror‐Image Strategy

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