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Safety, Pharmacokinetics, and Pharmacodynamics of a Single Bolus of the γ-aminobutyric Acid (GABA) Receptor Potentiator HSK3486 in Healthy Chinese Elderly and Non-elderly

Frontiers in pharmacology, 2021-08, Vol.12, p.735700-735700

2021

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ITRAQ-Based Proteomics Analysis of Triptolide On Human A549 Lung Adenocarcinoma Cells

Cellular physiology and biochemistry, 2018-01, Vol.45 (3), p.917-934

2018

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A phase I study to evaluate the safety, tolerability, and pharmacokinetics of a novel, potent GABA analog HSK16149 in healthy Chinese subjects

Frontiers in pharmacology, 2023-12, Vol.14, p.1296672-1296672

2023

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Safety and effectiveness of HSK21542 for hemodialysis patients: a multiple ascending dose study

Frontiers in pharmacology, 2023-10, Vol.14, p.1203642-1203642

2023

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Design, Synthesis, and Evaluation of a Series of Novel Benzocyclobutene Derivatives as General Anesthetics

Journal of medicinal chemistry, 2017-05, Vol.60 (9), p.3618-3625

2017

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Effect of a high‐fat and high‐calorie food on the pharmacokinetics of a novel, potent GABA analog HSK16149 in healthy subjects

Pharmacology research & perspectives, 2023-06, Vol.11 (3), p.e01102-n/a

2023

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Cannabinoid CB1 receptor antagonist rimonabant attenuates reinstatement of ketamine conditioned place preference in rats

European journal of pharmacology, 2008-07, Vol.589 (1-3), p.122-126

2008

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Design, Synthesis, and Evaluation of Novel 2,6-Disubstituted Phenol Derivatives as General Anesthetics

Journal of medicinal chemistry, 2017-05, Vol.60 (9), p.3606-3617

2017

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Guizhi Shaoyao Zhimu granules attenuate bone destruction in mice with collagen-induced arthritis by promoting mitophagy of osteoclast precursors to inhibit osteoclastogenesis

Phytomedicine (Stuttgart), 2023-09, Vol.118, p.154967-154967, Article 154967

2023

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Characterization of bacterial community dynamics in a full-scale drinking water treatment plant

Journal of environmental sciences (China), 2017, Vol.51 (1), p.21-30

2017

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Assessments of Onset and Duration of Drug Effects and Pharmacokinetics by Dose Level of HSK3486, a New Sedative-Hypnotic Agent, in Healthy Female/Male Subjects: A Phase I Multiarm Randomized Controlled Clinical Trial [Retracted]

Anesthesia and analgesia, 2021-01

2021

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Acetyllevocarnitine hydrochloride for the treatment of diabetic peripheral neuropathy: A phase 3, randomized clinical trial in China

Diabetes (New York, N.Y.), 2024-05, Vol.73 (5), p.797-805

2024

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A model‐informed approach to accelerate the clinical development of cofrogliptin (HSK7653), a novel ultralong‐acting dipeptidyl peptidase‐4 inhibitor

Diabetes, obesity & metabolism, 2024-02, Vol.26 (2), p.592-601

2024

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Triptolide inhibits epithelial‑mesenchymal transition and induces apoptosis in gefitinib‑resistant lung cancer cells

Oncology reports, 2020-05, Vol.43 (5), p.1569-1579

2020

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Computational ghost imaging based on negative film imaging

Optik (Stuttgart), 2023-08, Vol.284, p.170932, Article 170932

2023

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Convergence for Imaginary Time Step evolution in the Fermi and Dirac seas

Science China. Physics, mechanics & astronomy, 2010-02, Vol.53 (2), p.327-330

2010

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Triptolide Inhibits Breast Cancer Cell Metastasis Through Inducing the Expression of miR-146a, a Negative Regulator of Rho GTPase

Oncology research, 2019-09, Vol.27 (9), p.1043-1050

2019

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Optimization of the imaginary time step evolution for the Dirac equation

Science China. Physics, mechanics & astronomy, 2011-02, Vol.54 (2), p.231-235

2011

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Determining the Clinical Value and Critical Pathway of GTPBP4 in Lung Adenocarcinoma Using a Bioinformatics Strategy: A Study Based on Datasets from The Cancer Genome Atlas

BioMed research international, 2020, Vol.2020 (2020), p.1-13

2020

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A Multicenter, Randomized, Double-Blind, Placebo-Controlled, and Dose-Increasing Study on the Safety, Tolerability and PK/PD of Multiple Doses of HSK7653 by Oral Administration in Patients with Type 2 Diabetes Mellitus in China

Diabetes therapy, 2024-01, Vol.15 (1), p.183-199

2024

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Development and validation of an HPLC coupled with tandem mass spectrometry method for the determination of HSK7653, a novel super long‐acting dipeptidyl peptidase‐4 inhibitor, in human plasma and urine and its application to a pharmacokinetic study

Biomedical chromatography, 2023-05, Vol.37 (5), p.e5607-n/a

2023

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Concentration‐QTc Modeling of the DPP‐4 Inhibitor HSK7653 in a First‐in‐Human Study of Chinese Healthy Volunteers

Clinical pharmacology in drug development, 2024-07, Vol.13 (7), p.716-728

2024

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CENPE promotes glioblastomas proliferation by directly binding to WEE1

Translational cancer research, 2020-02, Vol.9 (2), p.717-725

2020

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Cannabinoid CB(1) receptor antagonist rimonabant attenuates reinstatement of ketamine conditioned place preference in rats

European journal of pharmacology, 2008-07, Vol.589 (1-3), p.122

2008

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Safety, Pharmacokinetics, and Pharmacodynamics of a Single Bolus of the γ-aminobutyric Acid (GABA) Receptor Potentiator HSK3486 in Healthy Chinese Elderly and Non-elderly

ITRAQ-Based Proteomics Analysis of Triptolide On Human A549 Lung Adenocarcinoma Cells

A phase I study to evaluate the safety, tolerability, and pharmacokinetics of a novel, potent GABA analog HSK16149 in healthy Chinese subjects

Safety and effectiveness of HSK21542 for hemodialysis patients: a multiple ascending dose study

Design, Synthesis, and Evaluation of a Series of Novel Benzocyclobutene Derivatives as General Anesthetics

Effect of a high‐fat and high‐calorie food on the pharmacokinetics of a novel, potent GABA analog HSK16149 in healthy subjects

Cannabinoid CB1 receptor antagonist rimonabant attenuates reinstatement of ketamine conditioned place preference in rats

Design, Synthesis, and Evaluation of Novel 2,6-Disubstituted Phenol Derivatives as General Anesthetics

Guizhi Shaoyao Zhimu granules attenuate bone destruction in mice with collagen-induced arthritis by promoting mitophagy of osteoclast precursors to inhibit osteoclastogenesis

Characterization of bacterial community dynamics in a full-scale drinking water treatment plant

Assessments of Onset and Duration of Drug Effects and Pharmacokinetics by Dose Level of HSK3486, a New Sedative-Hypnotic Agent, in Healthy Female/Male Subjects: A Phase I Multiarm Randomized Controlled Clinical Trial [Retracted]

Acetyllevocarnitine hydrochloride for the treatment of diabetic peripheral neuropathy: A phase 3, randomized clinical trial in China

A model‐informed approach to accelerate the clinical development of cofrogliptin (HSK7653), a novel ultralong‐acting dipeptidyl peptidase‐4 inhibitor

Triptolide inhibits epithelial‑mesenchymal transition and induces apoptosis in gefitinib‑resistant lung cancer cells

Computational ghost imaging based on negative film imaging

Convergence for Imaginary Time Step evolution in the Fermi and Dirac seas

Triptolide Inhibits Breast Cancer Cell Metastasis Through Inducing the Expression of miR-146a, a Negative Regulator of Rho GTPase

Optimization of the imaginary time step evolution for the Dirac equation

Determining the Clinical Value and Critical Pathway of GTPBP4 in Lung Adenocarcinoma Using a Bioinformatics Strategy: A Study Based on Datasets from The Cancer Genome Atlas

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, and Dose-Increasing Study on the Safety, Tolerability and PK/PD of Multiple Doses of HSK7653 by Oral Administration in Patients with Type 2 Diabetes Mellitus in China

Development and validation of an HPLC coupled with tandem mass spectrometry method for the determination of HSK7653, a novel super long‐acting dipeptidyl peptidase‐4 inhibitor, in human plasma and urine and its application to a pharmacokinetic study

Efficacy and Safety of Crisugabalin (HSK16149) in Adults with Postherpetic Neuralgia: A Phase 3 Randomized Clinical Trial

Concentration‐QTc Modeling of the DPP‐4 Inhibitor HSK7653 in a First‐in‐Human Study of Chinese Healthy Volunteers

CENPE promotes glioblastomas proliferation by directly binding to WEE1

Cannabinoid CB(1) receptor antagonist rimonabant attenuates reinstatement of ketamine conditioned place preference in rats

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