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Global dynamics of proteins: bridging between structure and function

Annual review of biophysics, 2010-06, Vol.39 (1), p.23-42

2010

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Normal Mode Analysis of Biomolecular Structures: Functional Mechanisms of Membrane Proteins

Chemical reviews, 2010-03, Vol.110 (3), p.1463-1497

2010

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Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release

Proceedings of the National Academy of Sciences - PNAS, 2017-09, Vol.114 (38), p.E7997-E8006

2017

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Using the principle of entropy maximization to infer genetic interaction networks from gene expression patterns

Proceedings of the National Academy of Sciences - PNAS, 2006-12, Vol.103 (50), p.19033-19038

2006

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Inhibition of RPS6K reveals context-dependent Akt activity in luminal breast cancer cells

PLoS computational biology, 2021-06, Vol.17 (6), p.e1009125-e1009125

2021

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Using entropy maximization to understand the determinants of structural dynamics beyond native contact topology

PLoS computational biology, 2010-06, Vol.6 (6), p.e1000816-e1000816

2010

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Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery

PloS one, 2014-07, Vol.9 (7), p.e102678-e102678

2014

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Evol and ProDy for bridging protein sequence evolution and structural dynamics

Bioinformatics (Oxford, England), 2014-09, Vol.30 (18), p.2681-2683

2014

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Global motions of the nuclear pore complex: insights from elastic network models

PLoS computational biology, 2009-09, Vol.5 (9), p.e1000496-e1000496

2009

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Predicting the Effects of Drug Combinations Using Probabilistic Matrix Factorization

Frontiers in bioinformatics, 2021-08, Vol.1, p.708815-708815

2021

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Modeling global changes induced by local perturbations to the HIV-1 capsid

Journal of molecular graphics & modelling, 2017-01, Vol.71, p.218-226

2017

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The effects of rigid motions on elastic network model force constants

Proteins, structure, function, and bioinformatics, 2012-04, Vol.80 (4), p.1133-1142

Lezon, Timothy R.

2012

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Pointwise mutual information quantifies intratumor heterogeneity in tissue sections labeled with multiple fluorescent biomarkers

Journal of pathology informatics, 2016, Vol.7 (1), p.47-47, Article 47

2016

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Platform for Quantitative Evaluation of Spatial Intratumoral Heterogeneity in Multiplexed Fluorescence Images

Cancer research (Chicago, Ill.), 2017-11, Vol.77 (21), p.e71-e74

2017

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Harnessing Human Microphysiology Systems as Key Experimental Models for Quantitative Systems Pharmacology

Concepts and Principles of Pharmacology, 2019, Vol.260, p.327-367

2019

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Proteomic Screening and Lasso Regression Reveal Differential Signaling in Insulin and Insulin-like Growth Factor I (IGF1) Pathways

Molecular & cellular proteomics, 2016-09, Vol.15 (9), p.3045-3057

2016

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Connecting Neuronal Cell Protective Pathways and Drug Combinations in a Huntington’s Disease Model through the Application of Quantitative Systems Pharmacology

Scientific reports, 2017-12, Vol.7 (1), p.17803-16, Article 17803

2017

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Constraints Imposed by the Membrane Selectively Guide the Alternating Access Dynamics of the Glutamate Transporter GltPh

Biophysical journal, 2012-03, Vol.102 (6), p.1331-1340

2012

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Global Changes Induced by Local Perturbations to the HIV-1 Capsid

Biophysical journal, 2016-02, Vol.110 (3), p.382a-382a

2016

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The origami of life

Journal of physics. Condensed matter, 2006-01, Vol.18 (3), p.847-888

2006

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What determines the spectrum of protein native state structures?

Proteins, structure, function, and bioinformatics, 2006-05, Vol.63 (2), p.273-277

2006

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Constraints Imposed by the Membrane Selectively Guide the Alternating Access Dynamics of the Glutamate Transporter Glt^sub Ph

Biophysical journal, 2012-03, Vol.102 (6), p.1331

2012

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Constraints Imposed by the Membrane Selectively Guide the Alternating Access Dynamics of the Glutamate Transporter GltPₕ

Biophysical journal, 2012, Vol.102 (6), p.1331-1340

2012

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Abstract 1880: Determining the role of E-cadherin in regulating IGF1 signaling in breast cancer: An interaction predicted by large-scale modeling

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1880-1880

2016

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Using Entropy Maximization to Understand the Determinants of Structural Dynamics beyond Native Contact Topology: e1000816

PLoS computational biology, 2010-06, Vol.6 (6)

2010

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Global dynamics of proteins: bridging between structure and function

Normal Mode Analysis of Biomolecular Structures: Functional Mechanisms of Membrane Proteins

Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release

Using the principle of entropy maximization to infer genetic interaction networks from gene expression patterns

Inhibition of RPS6K reveals context-dependent Akt activity in luminal breast cancer cells

Using entropy maximization to understand the determinants of structural dynamics beyond native contact topology

Identifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discovery

Evol and ProDy for bridging protein sequence evolution and structural dynamics

Global motions of the nuclear pore complex: insights from elastic network models

Predicting the Effects of Drug Combinations Using Probabilistic Matrix Factorization

Modeling global changes induced by local perturbations to the HIV-1 capsid

The effects of rigid motions on elastic network model force constants

Pointwise mutual information quantifies intratumor heterogeneity in tissue sections labeled with multiple fluorescent biomarkers

Platform for Quantitative Evaluation of Spatial Intratumoral Heterogeneity in Multiplexed Fluorescence Images

Harnessing Human Microphysiology Systems as Key Experimental Models for Quantitative Systems Pharmacology

Proteomic Screening and Lasso Regression Reveal Differential Signaling in Insulin and Insulin-like Growth Factor I (IGF1) Pathways

Connecting Neuronal Cell Protective Pathways and Drug Combinations in a Huntington’s Disease Model through the Application of Quantitative Systems Pharmacology

Constraints Imposed by the Membrane Selectively Guide the Alternating Access Dynamics of the Glutamate Transporter GltPh

Global Changes Induced by Local Perturbations to the HIV-1 Capsid

The origami of life

What determines the spectrum of protein native state structures?

Constraints Imposed by the Membrane Selectively Guide the Alternating Access Dynamics of the Glutamate Transporter Glt^sub Ph

Constraints Imposed by the Membrane Selectively Guide the Alternating Access Dynamics of the Glutamate Transporter GltPₕ

Abstract 1880: Determining the role of E-cadherin in regulating IGF1 signaling in breast cancer: An interaction predicted by large-scale modeling

Using Entropy Maximization to Understand the Determinants of Structural Dynamics beyond Native Contact Topology: e1000816

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