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ABIN-2, of the TPL-2 Signaling Complex, Modulates Mammalian Inflammation

Trends in immunology, 2019-09, Vol.40 (9), p.799-808

2019

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Expression, biological activities and mechanisms of action of A20 (TNFAIP3)

Biochemical pharmacology, 2010-12, Vol.80 (12), p.2009-2020

2010

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Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation

Biochemical journal, 2016-06, Vol.473 (12), p.1759-1768

2016

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Mitogen-activated protein kinases in innate immunity

Nature reviews. Immunology, 2013-09, Vol.13 (9), p.679

2013

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p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (28), p.11200-11205

2012

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ABIN2 Function Is Required To Suppress DSS-Induced Colitis by a Tpl2-Independent Mechanism

The Journal of immunology (1950), 2018-12, Vol.201 (11), p.3373-3382

2018

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NF-κB signaling mediates homeostatic maturation of new T cells

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (9), p.3212-3212

2014

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Coordinate Regulation of TPL-2 and NF-κB Signaling in Macrophages by NF-κB1 p105

Molecular and Cellular Biology, 2012-09, Vol.32 (17), p.3438-3451

2012

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p38γ and p38δ modulate innate immune response by regulating MEF2D activation

eLife, 2023-07, Vol.12

2023

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IκB kinase-induced interaction of TPL-2 kinase with 14-3-3 is essential for Toll-like receptor activation of ERK-1 and -2 MAP kinases

Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (23), p.E2394-E2403

2014

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TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus

PLoS pathogens, 2017-07, Vol.13 (7), p.e1006536-e1006536

2017

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IκB Kinase 2 Regulates TPL-2 Activation of Extracellular Signal-Regulated Kinases 1 and 2 by Direct Phosphorylation of TPL-2 Serine 400

Molecular and Cellular Biology, 2012-11, Vol.32 (22), p.4684-4690

2012

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TPL-2 Regulates Macrophage Lipid Metabolism and M2 Differentiation to Control TH2-Mediated Immunopathology

PLoS pathogens, 2016-08, Vol.12 (8), p.e1005783-e1005783

2016

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Regulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinase

Cell research, 2011-01, Vol.21 (1), p.131-145

2011

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Tumor progression locus 2 reduces severe allergic airway inflammation by inhibiting Ccl24 production in dendritic cells

Journal of allergy and clinical immunology, 2017-02, Vol.139 (2), p.655-666.e7

2017

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Ebola virus VP35 induces high-level production of recombinant TPL-2-ABIN-2-NF-κB1 p105 complex in co-transfected HEK-293 cells

Biochemical journal, 2013-06, Vol.452 (2), p.359-365

2013

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A20 inactivation in ocular adnexal MALT lymphoma

Haematologica (Roma), 2012-06, Vol.97 (6), p.926-930

2012

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IκB kinase regulation of the TPL-2/ERK MAPK pathway

Immunological reviews, 2012-03, Vol.246 (1), p.168-182

2012

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New insights into NF-κB regulation and function

Trends in immunology, 2008-10, Vol.29 (10), p.469-478

2008

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Functions of NF-κB1 and NF-κB2 in immune cell biology

Biochemical journal, 2004-09, Vol.382 (2), p.393-409

2004

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Identification of a Macrophage-Specific Chromatin Signature in the IL-10 Locus

The Journal of immunology (1950), 2005-07, Vol.175 (2), p.1041-1046

2005

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TNF activation of NF-κB is essential for development of single-positive thymocytes

The Journal of experimental medicine, 2016-07, Vol.213 (8), p.1399-1407

2016

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TPL-2-mediated activation of MAPK downstream of TLR4 signaling is coupled to arginine availability

Science signaling, 2010-08, Vol.3 (135), p.ra61

2010

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TPL-2 Inhibits IFN-β Expression via an ERK1/2-TCF-FOS Axis in TLR4-Stimulated Macrophages

The Journal of immunology (1950), 2022-02, Vol.208 (4), p.941-954

2022

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TPL‐2 kinase induces phagosome acidification to promote macrophage killing of bacteria

The EMBO journal, 2021-05, Vol.40 (10), p.e106188-n/a

2021

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ABIN-2, of the TPL-2 Signaling Complex, Modulates Mammalian Inflammation

Expression, biological activities and mechanisms of action of A20 (TNFAIP3)

Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation

Mitogen-activated protein kinases in innate immunity

p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation

ABIN2 Function Is Required To Suppress DSS-Induced Colitis by a Tpl2-Independent Mechanism

NF-κB signaling mediates homeostatic maturation of new T cells

Coordinate Regulation of TPL-2 and NF-κB Signaling in Macrophages by NF-κB1 p105

p38γ and p38δ modulate innate immune response by regulating MEF2D activation

IκB kinase-induced interaction of TPL-2 kinase with 14-3-3 is essential for Toll-like receptor activation of ERK-1 and -2 MAP kinases

TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus

IκB Kinase 2 Regulates TPL-2 Activation of Extracellular Signal-Regulated Kinases 1 and 2 by Direct Phosphorylation of TPL-2 Serine 400

TPL-2 Regulates Macrophage Lipid Metabolism and M2 Differentiation to Control TH2-Mediated Immunopathology

Regulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinase

Tumor progression locus 2 reduces severe allergic airway inflammation by inhibiting Ccl24 production in dendritic cells

Ebola virus VP35 induces high-level production of recombinant TPL-2-ABIN-2-NF-κB1 p105 complex in co-transfected HEK-293 cells

A20 inactivation in ocular adnexal MALT lymphoma

IκB kinase regulation of the TPL-2/ERK MAPK pathway

New insights into NF-κB regulation and function

Functions of NF-κB1 and NF-κB2 in immune cell biology

Identification of a Macrophage-Specific Chromatin Signature in the IL-10 Locus

TNF activation of NF-κB is essential for development of single-positive thymocytes

TPL-2-mediated activation of MAPK downstream of TLR4 signaling is coupled to arginine availability

TPL-2 Inhibits IFN-β Expression via an ERK1/2-TCF-FOS Axis in TLR4-Stimulated Macrophages

TPL‐2 kinase induces phagosome acidification to promote macrophage killing of bacteria

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